TY - JOUR
T1 - The Taenia solium glucose transporters TGTP1 and TGTP2 are not immunologically recognized by cysticercotic humans and swine
AU - Rodríguez-Contreras, D.
AU - De la Torre, P.
AU - Velasco, J.
AU - Shoemaker, C.
AU - Laclette, J.
N1 - Funding Information:
Acknowledgements This work was supported in part by grants from CONACYT, LOO42-M9607; from DGAPA-UNAM, IN-207195 (J.P.L.) and PADEP-UNAM 030361 (D.R.C.).
PY - 2002
Y1 - 2002
N2 - Cysticercosis caused by the metacestode of the tapeworm Taenia solium causes economic losses in pork meat production, as well as being a human health hazard in some parts of the world. In order to determine if the glucose transporters TGTP1 and TGTP2 are recognized by antibodies in the sera from cysticercotic humans and pigs, western blot assays were carried out using membrane fractions of insect cells expressing the two T. solium glucose transporters. Results demonstrated a complete lack of recognition of both TGTPs. These results are unexpected, because at least one transporter is present on the apical surface of the cysticercus tegument.
AB - Cysticercosis caused by the metacestode of the tapeworm Taenia solium causes economic losses in pork meat production, as well as being a human health hazard in some parts of the world. In order to determine if the glucose transporters TGTP1 and TGTP2 are recognized by antibodies in the sera from cysticercotic humans and pigs, western blot assays were carried out using membrane fractions of insect cells expressing the two T. solium glucose transporters. Results demonstrated a complete lack of recognition of both TGTPs. These results are unexpected, because at least one transporter is present on the apical surface of the cysticercus tegument.
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U2 - 10.1007/s00436-001-0528-9
DO - 10.1007/s00436-001-0528-9
M3 - Article
C2 - 11954917
AN - SCOPUS:0036169338
SN - 0932-0113
VL - 88
SP - 280
EP - 282
JO - Parasitology Research
JF - Parasitology Research
IS - 3
ER -