The value of magnesium in flush solutions for human cadaveric kidney preservation

G. M. Collins; J. M. Barry; J. G. Maxwell; D. Sampson; B. A. Vander Werf

doi:10.1016/S0022-5347(17)50315-8

The value of magnesium in flush solutions for human cadaveric kidney preservation

G. M. Collins, J. M. Barry, J. G. Maxwell, D. Sampson, B. A. Vander Werf

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

A cooperative clinical trial was conducted among 5 transplant centers in the western United States to determine the value of magnesium sulfate in intracellular electrolyte flush solutions for hypothermic, human kidney storage. Kidneys from alternate donors were flushed with either magnesium-free Euro-Collins' solution or magnesium-containing Collins' 2 solution. Donor and recipient ages, and mean preservation times were not significantly different between the 2 groups. There was a significantly lower dialysis requirement during the first week in the magnesium-containing Collins 2 group (33%) versus the Euro-Collins group (54%). Function rates and serum creatinine nadirs at 1 month were not significantly different. The beneficial effect of magnesium sulfate was more evident when preservation times exceeded 24 hours.

Original language	English (US)
Pages (from-to)	220-222
Number of pages	3
Journal	Journal of Urology
Volume	131
Issue number	2
DOIs	https://doi.org/10.1016/S0022-5347(17)50315-8
State	Published - Jan 1 1984
Externally published	Yes

ASJC Scopus subject areas

Urology

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abstract = "A cooperative clinical trial was conducted among 5 transplant centers in the western United States to determine the value of magnesium sulfate in intracellular electrolyte flush solutions for hypothermic, human kidney storage. Kidneys from alternate donors were flushed with either magnesium-free Euro-Collins' solution or magnesium-containing Collins' 2 solution. Donor and recipient ages, and mean preservation times were not significantly different between the 2 groups. There was a significantly lower dialysis requirement during the first week in the magnesium-containing Collins 2 group (33%) versus the Euro-Collins group (54%). Function rates and serum creatinine nadirs at 1 month were not significantly different. The beneficial effect of magnesium sulfate was more evident when preservation times exceeded 24 hours.",

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AU - Barry, J. M.

AU - Maxwell, J. G.

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AU - Vander Werf, B. A.

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AB - A cooperative clinical trial was conducted among 5 transplant centers in the western United States to determine the value of magnesium sulfate in intracellular electrolyte flush solutions for hypothermic, human kidney storage. Kidneys from alternate donors were flushed with either magnesium-free Euro-Collins' solution or magnesium-containing Collins' 2 solution. Donor and recipient ages, and mean preservation times were not significantly different between the 2 groups. There was a significantly lower dialysis requirement during the first week in the magnesium-containing Collins 2 group (33%) versus the Euro-Collins group (54%). Function rates and serum creatinine nadirs at 1 month were not significantly different. The beneficial effect of magnesium sulfate was more evident when preservation times exceeded 24 hours.

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The value of magnesium in flush solutions for human cadaveric kidney preservation

Abstract

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