Thrombocytopenia associated with sodium valproate treatment

Andreas N. Neophytides, John G. Nutt, Jules R. Lodish

Research output: Contribution to journalArticlepeer-review

65 Scopus citations


The administration of sodium valproate to 30 patients in daily doses of 1,200 to 3,000 mg was associated with a significant reduction of the platelet count. Thrombocytopenia without any concomitant bleeding abnormalities occurred in 10 of the patients. Platelet counts returned to baseline levels after withdrawal of the drug.

Original languageEnglish (US)
Pages (from-to)389-390
Number of pages2
JournalAnnals of Neurology
Issue number4
StatePublished - Apr 1979
Externally publishedYes

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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