TY - JOUR
T1 - Thrombotic thrombocytopenic purpura in a patient with very early pregnancy
T2 - Clinical presentation and autopsy findings
AU - Sharma, Aman
AU - Radotra, Bishan
AU - Wanchu, Ajay
AU - Malhotra, Pankaj
AU - Singh, Surjit
AU - Varma, Subhash
PY - 2008/10
Y1 - 2008/10
N2 - Thrombotic thrombocytopenic purpura is a thrombotic microangiopathy leading to microvascular occlusion resulting in ischemic dysfunction of various organs. Pregnancy has been thought to precipitate it during second and third trimester, but its reports in first trimester are extremely rare. We report the clinical protocol of a young lady with 5-week period of gestation, who presented with fever, seizures and altered sensorium, and succumbed to her illness during an episode of seizure. Complete autopsy findings are also presented in detail.
AB - Thrombotic thrombocytopenic purpura is a thrombotic microangiopathy leading to microvascular occlusion resulting in ischemic dysfunction of various organs. Pregnancy has been thought to precipitate it during second and third trimester, but its reports in first trimester are extremely rare. We report the clinical protocol of a young lady with 5-week period of gestation, who presented with fever, seizures and altered sensorium, and succumbed to her illness during an episode of seizure. Complete autopsy findings are also presented in detail.
KW - Histopathological findings
KW - Pregnancy
KW - Thrombotic thrombocytopenic purpura
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UR - http://www.scopus.com/inward/citedby.url?scp=55049139370&partnerID=8YFLogxK
U2 - 10.1097/MBC.0b013e32830ef8de
DO - 10.1097/MBC.0b013e32830ef8de
M3 - Article
C2 - 18832919
AN - SCOPUS:55049139370
SN - 0957-5235
VL - 19
SP - 727
EP - 730
JO - Blood Coagulation and Fibrinolysis
JF - Blood Coagulation and Fibrinolysis
IS - 7
ER -