Through a glass darkly: Salt transport by the distal tubule

Research output: Contribution to journalComment/debatepeer-review

4 Scopus citations


The distal convoluted tubule (DCT) plays a central role in blood pressure and potassium homeostasis, as evidenced by diseases that occur when its function is modified. The paper by van der Lubbe and colleagues makes clear that angiotensin II itself increases the activity and abundance of the thiazide-sensitive Na-Cl cotransporter (NCC), independent of changes in circulating aldosterone. This Commentary provides additional perspective on that work.

Original languageEnglish (US)
Pages (from-to)5-8
Number of pages4
JournalKidney International
Issue number1
StatePublished - Jan 2011

ASJC Scopus subject areas

  • Nephrology


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