TY - JOUR
T1 - Tranexamic Acid Prevention of Hemorrhagic Complications Following Interpolated Flap Repair
T2 - A Single-Center, Retrospective, Cohort Study
AU - Freeman, S. Caleb
AU - Heath, Michael S.
AU - Neill, Brett
AU - Morris, Caroline
AU - Lucero, Olivia M.
AU - Yu, Wesley
AU - Bar, Anna
AU - Leitenberger, Justin J.
N1 - Publisher Copyright:
© 2023 Lippincott Williams and Wilkins. All rights reserved.
PY - 2023/12/1
Y1 - 2023/12/1
N2 - BACKGROUNDTranexamic acid (TXA) is increasingly being used to prevent hemorrhagic complications after dermatologic surgery. Interpolated flap repairs following Mohs micrographic surgery are at risk for increased bleeding events and unplanned health care utilization, particularly among patients on antithrombotic medication.OBJECTIVETo assess bleeding events after interpolated flap repair in patients receiving TXA compared with those who did not.MATERIALS AND METHODSA retrospective review identified interpolated flap repairs in a 5-year period. Hemorrhagic complications were analyzed, defined as major bleeding events, which included all unplanned medical visits, and minor bleeding events, which included any unplanned patient phone calls or messages through electronic medical record.RESULTSOne hundred fifteen patients had interpolated flap repair during the 5-year period, of which 21 (18.3%) received TXA postprocedure. Twenty-seven bleeding events were identified in the non-TXA group compared with 1 event in the TXA-treated group. Patients who received TXA were less likely to have had a bleeding event (28.7% vs 4.8%, p <.01).CONCLUSIONPatients undergoing interpolation flap repair were less likely to experience a bleeding event after subcutaneous injection of TXA.
AB - BACKGROUNDTranexamic acid (TXA) is increasingly being used to prevent hemorrhagic complications after dermatologic surgery. Interpolated flap repairs following Mohs micrographic surgery are at risk for increased bleeding events and unplanned health care utilization, particularly among patients on antithrombotic medication.OBJECTIVETo assess bleeding events after interpolated flap repair in patients receiving TXA compared with those who did not.MATERIALS AND METHODSA retrospective review identified interpolated flap repairs in a 5-year period. Hemorrhagic complications were analyzed, defined as major bleeding events, which included all unplanned medical visits, and minor bleeding events, which included any unplanned patient phone calls or messages through electronic medical record.RESULTSOne hundred fifteen patients had interpolated flap repair during the 5-year period, of which 21 (18.3%) received TXA postprocedure. Twenty-seven bleeding events were identified in the non-TXA group compared with 1 event in the TXA-treated group. Patients who received TXA were less likely to have had a bleeding event (28.7% vs 4.8%, p <.01).CONCLUSIONPatients undergoing interpolation flap repair were less likely to experience a bleeding event after subcutaneous injection of TXA.
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U2 - 10.1097/DSS.0000000000003931
DO - 10.1097/DSS.0000000000003931
M3 - Article
C2 - 37712760
AN - SCOPUS:85178499723
SN - 1076-0512
VL - 49
SP - 1139
EP - 1142
JO - Dermatologic Surgery
JF - Dermatologic Surgery
IS - 12
ER -