Transcription of chromatin: These are complex times

Jennifer A. Armstrong, Beverly M. Emerson

Research output: Contribution to journalArticlepeer-review

80 Scopus citations

Abstract

Transcription of chromatin-packaged genes involves highly regulated changes in nucleosomal structure that control DNA accessibility. Two systems that facilitate these changes are ATP-dependent chromatin remodeling complexes and enzymatic complexes which control histone acetylation and deacetylation. Recent studies provide insight on the role of these remodeling machines and specific transcription factors in the expression of viral, inducible, and tissue-restricted genes.

Original languageEnglish (US)
Pages (from-to)165-172
Number of pages8
JournalCurrent Opinion in Genetics and Development
Volume8
Issue number2
DOIs
StatePublished - Apr 1998
Externally publishedYes

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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