Transgenic and gene "knockout" models in alcohol research

P. L. Hoffman, T. Yagi, B. Tabakoff, T. J. Phillips, H. Kono, R. O. Messing, D. S. Choi

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


This article represents the proceedings of a symposium at the 2000 ISBRA Meeting in Yokohama, Japan. The chairs were Paula L. Hoffman and Takeshi Yagi. The presentations were (1) cAMP signaling in ethanol sensitivity and tolerance, by Boris Tabakoff; (2) Synaptic signaling pathways of Fyn-tyrosine kinase, by Takeshi Yagi; (3) Ethanol drinking and sensitization in dopaminergic and serotonergic receptor knockouts, by Tamara J. Phillips; (4) ICAM-1 is involved in early alcohol-induced liver injury in the mouse given enteral alcohol, by Hiroshi Kono; and (5) Strategies for targeted and regulated knockouts, by Robert O. Messing and Doo-Sup Choi.

Original languageEnglish (US)
Pages (from-to)60S-66S
JournalAlcoholism: Clinical and Experimental Research
Issue number5 SUPPL.
StatePublished - 2001
Externally publishedYes


  • Dopamine
  • Fyn-tyrosine kinase
  • ICAM-1
  • Knockout model
  • Serotonin
  • cAMP

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health


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