Translational in vivo models for women’s health: The nonhuman primate endometrium—a predictive model for assessing steroid receptor modulators

Research output: Chapter in Book/Report/Conference proceedingChapter

5 Scopus citations

Abstract

Macaques and baboons display physiological responses to steroid hormones that are similar to those of women. Herein, we describe various uses of nonhuman primates for preclinical studies on menstruation, endometriosis, and as a model system to evaluate reproductive therapies and contraceptives. Our goal is to outline the strengths of the nonhuman primate model for studies leading to improved therapies for women.

Original languageEnglish (US)
Title of host publicationHandbook of Experimental Pharmacology
PublisherSpringer New York LLC
Pages191-202
Number of pages12
DOIs
StatePublished - Apr 1 2016

Publication series

NameHandbook of Experimental Pharmacology
Volume232
ISSN (Print)0171-2004
ISSN (Electronic)1865-0325

Keywords

  • Animal models
  • Endometriosis
  • Menstruation
  • Nonhuman primate
  • Progesterone receptor modulators

ASJC Scopus subject areas

  • General Pharmacology, Toxicology and Pharmaceutics
  • Biochemistry

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