TY - JOUR
T1 - Two-dimensional echocardiographic evaluation of dilated cardiomyopathy in children
AU - Goldberg, Stanley J.
AU - Valdes-Cruz, Lilliam M.
AU - Sahn, David J.
AU - Allen, Hugh D.
N1 - Funding Information:
From the Department of Pediatrics, University of Arizona, Health Sciences Center, Tucson, Arizona. This study was supported in part by a grant from the Muscular Dystrophy Association, New York, New York. Manuscript received June 6, 1983; revised manuscript received August 22. 1983, accepted August 25, 1983.
PY - 1983/12/1
Y1 - 1983/12/1
N2 - This study examines and quantitates left ventricular (LV) short-axis 2-dimensional (2-D) echocardiograms of 16 normal control subjects and 19 patients who presented with clinical features suggestive of myocarditis leading to severe myocardiopathy. Of the 19 patients, 8 died or had cardiac transplantation: 9 were studied in the chronic phase and 10 in the acute phase. The endocardial surface of the LV short-axis image was digitized at chordal level at end-diastole and end-systole. Digitized traces in systole and diastole were superimposed. The cavity area of systole and diastole was determined and expressed as the percent systolic area reduction ratio. In the control subjects, the left ventricles were round in systole and diastole, contracted concentrically, and had a mean percent systolic area reduction of 53% (range 43 to 67). The left ventricle was not round in systole in the patients with myocarditis, and in 15, only the ventricular septum contracted significantly. Three patients had nonconcentric contraction, and regional contraction was more difficult to judge. The systolic area reduction ratio for the patients was 11 % (range 1 to 33), with no overlap with control subjects (p <0.001). Our results suggest that myocarditis more severely affects the LV free wall than the septum. In chronic patients, LV contraction remained markedly impaired. Quantitative evaluation of short-axis 2-D echocardiograms is a useful and sensitive technique for assessing damage due to presumed myocarditis.
AB - This study examines and quantitates left ventricular (LV) short-axis 2-dimensional (2-D) echocardiograms of 16 normal control subjects and 19 patients who presented with clinical features suggestive of myocarditis leading to severe myocardiopathy. Of the 19 patients, 8 died or had cardiac transplantation: 9 were studied in the chronic phase and 10 in the acute phase. The endocardial surface of the LV short-axis image was digitized at chordal level at end-diastole and end-systole. Digitized traces in systole and diastole were superimposed. The cavity area of systole and diastole was determined and expressed as the percent systolic area reduction ratio. In the control subjects, the left ventricles were round in systole and diastole, contracted concentrically, and had a mean percent systolic area reduction of 53% (range 43 to 67). The left ventricle was not round in systole in the patients with myocarditis, and in 15, only the ventricular septum contracted significantly. Three patients had nonconcentric contraction, and regional contraction was more difficult to judge. The systolic area reduction ratio for the patients was 11 % (range 1 to 33), with no overlap with control subjects (p <0.001). Our results suggest that myocarditis more severely affects the LV free wall than the septum. In chronic patients, LV contraction remained markedly impaired. Quantitative evaluation of short-axis 2-D echocardiograms is a useful and sensitive technique for assessing damage due to presumed myocarditis.
UR - http://www.scopus.com/inward/record.url?scp=0021060749&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021060749&partnerID=8YFLogxK
U2 - 10.1016/0002-9149(83)90581-7
DO - 10.1016/0002-9149(83)90581-7
M3 - Article
C2 - 6650412
AN - SCOPUS:0021060749
SN - 0002-9149
VL - 52
SP - 1244
EP - 1248
JO - The American journal of cardiology
JF - The American journal of cardiology
IS - 10
ER -