Unintentional pediatric superwarfarin exposures: Do we really need a prothrombin time?

Michael E. Mullins, Christina L. Brands, Mohamud R. Daya

Research output: Contribution to journalArticlepeer-review

35 Scopus citations


Objective. To determine whether routine follow-up coagulation studies are useful in children with accidental exposures to rodenticides containing superwarfarin compounds. Design. Retrospective review of poison center charts involving pediatric superwarfarin exposures occurring in two 2-year periods. Setting. An American Association of Poison Control Centers-certified regional poison control center with an annual call volume of 55 000 calls per year from a 2-state area with a combined population of 4 million people. Outcome Measures. Prothrombin times and/or international normalized ratios and reported clinical signs of excessive anticoagulation after exposure. Results. Of 542 children in 4 years of data collection, follow-up prothrombin times and/or international normalized ratios measurements did not detect any significant coagulation abnormalities. No child developed bleeding complications. No child required or received antidotal treatment with vitamin K. Conclusion. Normal preschool-aged children with unintentional acute exposures to superwarfarin rodenticides do not require any routine follow-up laboratory studies and do not require any medical intervention.

Original languageEnglish (US)
Pages (from-to)402-404
Number of pages3
Issue number2
StatePublished - Feb 2000


  • Anticoagulant
  • Children
  • Poisoning
  • Rodenticide

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Unintentional pediatric superwarfarin exposures: Do we really need a prothrombin time?'. Together they form a unique fingerprint.

Cite this