Unobtrusive assessment of activity patterns associated with mild cognitive impairment

Tamara L. Hayes, Francena Abendroth, Andre Adami, Misha Pavel, Tracy A. Zitzelberger, Jeffrey A. Kaye

Research output: Contribution to journalArticlepeer-review

147 Scopus citations


Background: Timely detection of early cognitive impairment is difficult. Measures taken in the clinic reflect a single snapshot of performance that might be confounded by the increased variability typical in aging and disease. We evaluated the use of continuous, long-term, and unobtrusive in-home monitoring to assess neurologic function in healthy and cognitively impaired elders. Methods: Fourteen older adults 65 years and older living independently in the community were monitored in their homes by using an unobtrusive sensor system. Measures of walking speed and amount of activity in the home were obtained. Wavelet analysis was used to examine variance in activity at multiple time scales. Results: More than 108,000 person-hours of continuous activity data were collected during periods as long as 418 days (mean, 315 ± 82 days). The coefficient of variation in the median walking speed was twice as high in the mild cognitive impairment (MCI) group (0.147 ± 0.074) as compared with the healthy group (0.079 ± 0.027; t11 = 2.266, P < .03). Furthermore, the 24-hour wavelet variance was greater in the MCI group (MCI, 4.07 ± 0.14; healthy elderly, 3.79 ± 0.23; F = 7.58, P ≤ .008), indicating that the day-to-day pattern of activity of subjects in the MCI group was more variable than that of the cognitively healthy controls. Conclusions: The results not only demonstrate the feasibility of these methods but also suggest clear potential advantages to this new methodology. This approach might provide an improved means of detecting the earliest transition to MCI compared with conventional episodic testing in a clinic environment.

Original languageEnglish (US)
Pages (from-to)395-405
Number of pages11
JournalAlzheimer's and Dementia
Issue number6
StatePublished - Nov 2008


  • Assessment of cognitive disorders/dementia
  • Cognitive aging
  • In-home assessment
  • MCI (mild cognitive impairment)
  • Technology and aging

ASJC Scopus subject areas

  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Cellular and Molecular Neuroscience
  • Health Policy
  • Developmental Neuroscience
  • Epidemiology


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