Vaccine strategies for human papillomavirus-associated head and neck cancers

Jade Z. Zhou; Jessica Jou; Ezra Cohen

doi:10.3390/cancers14010033

Vaccine strategies for human papillomavirus-associated head and neck cancers

Jade Z. Zhou, Jessica Jou, Ezra Cohen

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

The rising incidence of oropharyngeal squamous cell cancers (OPSCC) in the United States is largely attributed to HPV. Prophylactic HPV vaccines have demonstrated effectiveness against oral infection of HPV 16 and HPV 18. We review the global epidemiology and biology of HPV-related cancers as well as the development of HPV vaccines and their use worldwide. We also review the various strategies and challenges in development of therapeutic HPV vaccines.

Original language	English (US)
Article number	33
Journal	Cancers
Volume	14
Issue number	1
DOIs	https://doi.org/10.3390/cancers14010033
State	Published - Jan 1 2022
Externally published	Yes

Keywords

Head and neck cancers
Human papillomavirus
Oropharyngeal cancer
Vaccines

ASJC Scopus subject areas

Oncology
Cancer Research

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10.3390/cancers14010033

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abstract = "The rising incidence of oropharyngeal squamous cell cancers (OPSCC) in the United States is largely attributed to HPV. Prophylactic HPV vaccines have demonstrated effectiveness against oral infection of HPV 16 and HPV 18. We review the global epidemiology and biology of HPV-related cancers as well as the development of HPV vaccines and their use worldwide. We also review the various strategies and challenges in development of therapeutic HPV vaccines.",

keywords = "Head and neck cancers, Human papillomavirus, Oropharyngeal cancer, Vaccines",

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AU - Jou, Jessica

AU - Cohen, Ezra

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N2 - The rising incidence of oropharyngeal squamous cell cancers (OPSCC) in the United States is largely attributed to HPV. Prophylactic HPV vaccines have demonstrated effectiveness against oral infection of HPV 16 and HPV 18. We review the global epidemiology and biology of HPV-related cancers as well as the development of HPV vaccines and their use worldwide. We also review the various strategies and challenges in development of therapeutic HPV vaccines.

AB - The rising incidence of oropharyngeal squamous cell cancers (OPSCC) in the United States is largely attributed to HPV. Prophylactic HPV vaccines have demonstrated effectiveness against oral infection of HPV 16 and HPV 18. We review the global epidemiology and biology of HPV-related cancers as well as the development of HPV vaccines and their use worldwide. We also review the various strategies and challenges in development of therapeutic HPV vaccines.

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KW - Human papillomavirus

KW - Oropharyngeal cancer

KW - Vaccines

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Vaccine strategies for human papillomavirus-associated head and neck cancers

Abstract

Keywords

ASJC Scopus subject areas

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