Variability of serial CT scans in subacute necrotizing encephalomyelopathy (leigh disease)

Thomas K. Koch, Warren D. Lo, Bruce O. Berg

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Computed tomographic (CT) brain scans of patients with subacute necrotizing encephalomyelopathy (SNE) may reveal focal lesions that correspond to sites of anatomic involvement of the disease. Three patients with SNE were followed with serial CT brain scans. In two patients radiographic abnormalities appeared well after the onset of clinical symptoms. In all three patients the radiographic lesions changed with time. This variability seen with serial scanning is an important feature of SNE.

Original languageEnglish (US)
Pages (from-to)48-51
Number of pages4
JournalPediatric Neurology
Issue number1
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology


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