Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS)

Sandra Weintraub; Lilah Besser; Hiroko H. Dodge; Merilee Teylan; Steven Ferris; Felicia C. Goldstein; Bruno Giordani; Joel Kramer; David Loewenstein; Dan Marson; Dan Mungas; David Salmon; Kathleen Welsh-Bohmer; Xiao Hua Zhou; Steven D. Shirk; Alireza Atri; Walter A. Kukull; Creighton Phelps; John C. Morris

doi:10.1097/WAD.0000000000000223

Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS)

Sandra Weintraub, Lilah Besser, Hiroko H. Dodge, Merilee Teylan, Steven Ferris, Felicia C. Goldstein, Bruno Giordani, Joel Kramer, David Loewenstein, Dan Marson, Dan Mungas, David Salmon, Kathleen Welsh-Bohmer, Xiao Hua Zhou, Steven D. Shirk, Alireza Atri, Walter A. Kukull, Creighton Phelps, John C. Morris

Neurology

Research output: Contribution to journal › Article › peer-review

314 Scopus citations

Abstract

Introduction: The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0. Methods: The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery. The UDSNB 3.0 covers episodic memory, processing speed, executive function, language, and constructional ability. Data from 3602 cognitively normal participants in the National Alzheimer Coordinating Center database were analyzed. Results: Descriptive statistics are presented. Multivariable linear regression analyses demonstrated score differences by age, sex, and education and were also used to create a normative calculator available online. Discussion: The UDSNB 3.0 neuropsychological battery provides a valuable non proprietary resource for conducting research on cognitive aging and dementia.

Original language	English (US)
Pages (from-to)	10-17
Number of pages	8
Journal	Alzheimer Disease and Associated Disorders
Volume	32
Issue number	1
DOIs	https://doi.org/10.1097/WAD.0000000000000223
State	Published - 2018

Keywords

UDS
cognition
dementia
neuropsychological test

ASJC Scopus subject areas

Clinical Psychology
Gerontology
Geriatrics and Gerontology
Psychiatry and Mental health

Access to Document

10.1097/WAD.0000000000000223

Cite this

Weintraub, S., Besser, L., Dodge, H. H., Teylan, M., Ferris, S., Goldstein, F. C., Giordani, B., Kramer, J., Loewenstein, D., Marson, D., Mungas, D., Salmon, D., Welsh-Bohmer, K., Zhou, X. H., Shirk, S. D., Atri, A., Kukull, W. A., Phelps, C., & Morris, J. C. (2018). Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS). Alzheimer Disease and Associated Disorders, 32(1), 10-17. https://doi.org/10.1097/WAD.0000000000000223

Weintraub, S, Besser, L, Dodge, HH, Teylan, M, Ferris, S, Goldstein, FC, Giordani, B, Kramer, J, Loewenstein, D, Marson, D, Mungas, D, Salmon, D, Welsh-Bohmer, K, Zhou, XH, Shirk, SD, Atri, A, Kukull, WA, Phelps, C & Morris, JC 2018, 'Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS)', Alzheimer Disease and Associated Disorders, vol. 32, no. 1, pp. 10-17. https://doi.org/10.1097/WAD.0000000000000223

@article{d71d896083854054ac1f8bb2c8538d48,

title = "Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS)",

abstract = "Introduction: The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0. Methods: The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery. The UDSNB 3.0 covers episodic memory, processing speed, executive function, language, and constructional ability. Data from 3602 cognitively normal participants in the National Alzheimer Coordinating Center database were analyzed. Results: Descriptive statistics are presented. Multivariable linear regression analyses demonstrated score differences by age, sex, and education and were also used to create a normative calculator available online. Discussion: The UDSNB 3.0 neuropsychological battery provides a valuable non proprietary resource for conducting research on cognitive aging and dementia.",

keywords = "UDS, cognition, dementia, neuropsychological test",

author = "Sandra Weintraub and Lilah Besser and Dodge, {Hiroko H.} and Merilee Teylan and Steven Ferris and Goldstein, {Felicia C.} and Bruno Giordani and Joel Kramer and David Loewenstein and Dan Marson and Dan Mungas and David Salmon and Kathleen Welsh-Bohmer and Zhou, {Xiao Hua} and Shirk, {Steven D.} and Alireza Atri and Kukull, {Walter A.} and Creighton Phelps and Morris, {John C.}",

note = "Publisher Copyright: {\textcopyright} 2017 The Author(s). Published by Wolters Kluwer Health, Inc.",

year = "2018",

doi = "10.1097/WAD.0000000000000223",

language = "English (US)",

volume = "32",

pages = "10--17",

journal = "Alzheimer Disease and Associated Disorders",

issn = "0893-0341",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

TY - JOUR

T1 - Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS)

AU - Weintraub, Sandra

AU - Besser, Lilah

AU - Dodge, Hiroko H.

AU - Teylan, Merilee

AU - Ferris, Steven

AU - Goldstein, Felicia C.

AU - Giordani, Bruno

AU - Kramer, Joel

AU - Loewenstein, David

AU - Marson, Dan

AU - Mungas, Dan

AU - Salmon, David

AU - Welsh-Bohmer, Kathleen

AU - Zhou, Xiao Hua

AU - Shirk, Steven D.

AU - Atri, Alireza

AU - Kukull, Walter A.

AU - Phelps, Creighton

AU - Morris, John C.

PY - 2018

Y1 - 2018

N2 - Introduction: The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0. Methods: The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery. The UDSNB 3.0 covers episodic memory, processing speed, executive function, language, and constructional ability. Data from 3602 cognitively normal participants in the National Alzheimer Coordinating Center database were analyzed. Results: Descriptive statistics are presented. Multivariable linear regression analyses demonstrated score differences by age, sex, and education and were also used to create a normative calculator available online. Discussion: The UDSNB 3.0 neuropsychological battery provides a valuable non proprietary resource for conducting research on cognitive aging and dementia.

AB - Introduction: The neuropsychological battery of the Uniform Data Set (UDSNB) was implemented in 2005 by the National Institute on Aging (NIA) Alzheimer Disease Centers program to measure cognitive performance in dementia and mild cognitive impairment due to Alzheimer Disease. This paper describes a revision, the UDSNB 3.0. Methods: The Neuropsychology Work Group of the NIA Clinical Task Force recommended revisions through a process of due diligence to address shortcomings of the original battery. The UDSNB 3.0 covers episodic memory, processing speed, executive function, language, and constructional ability. Data from 3602 cognitively normal participants in the National Alzheimer Coordinating Center database were analyzed. Results: Descriptive statistics are presented. Multivariable linear regression analyses demonstrated score differences by age, sex, and education and were also used to create a normative calculator available online. Discussion: The UDSNB 3.0 neuropsychological battery provides a valuable non proprietary resource for conducting research on cognitive aging and dementia.

KW - UDS

KW - cognition

KW - dementia

KW - neuropsychological test

UR - http://www.scopus.com/inward/record.url?scp=85041189693&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85041189693&partnerID=8YFLogxK

U2 - 10.1097/WAD.0000000000000223

DO - 10.1097/WAD.0000000000000223

M3 - Article

C2 - 29240561

AN - SCOPUS:85041189693

SN - 0893-0341

VL - 32

SP - 10

EP - 17

JO - Alzheimer Disease and Associated Disorders

JF - Alzheimer Disease and Associated Disorders

IS - 1

ER -

Version 3 of the Alzheimer Disease Centers' Neuropsychological Test Battery in the Uniform Data Set (UDS)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this