Visualizing the future: Enhancing neuroimaging with nanotechnology

Jesse L. Winer, Paul E. Kim, Meng Law, Charles Y. Liu, Michael L.J. Apuzzo

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


Advancements in imaging of the central nervous system have paralleled and propelled neurosurgical practice. These technologic innovations have expanded our understanding of neuroanatomy and neuropathology, helping to refine neurosurgical techniques to be more precise and less invasive. Nanotechnology will play a significant role in the next wave of technology that will continue to improve neurosurgical practice. With specific regard to neuroimaging, nanotechnology has the potential to provide more precise resolution when imaging nervous system malignancies. Nanoparticles may be engineered to noninvasively visualize pathology once found only under a microscope. They will enhance our ability to target new disease processes and thus develop more precise surgical and nonsurgical treatments. This article will discuss the background of nanotechnology's use in imaging of the nervous system, its current status, and future potentials.

Original languageEnglish (US)
Pages (from-to)626-637
Number of pages12
JournalWorld Neurosurgery
Issue number5-6
StatePublished - 2011
Externally publishedYes


  • Brain tumor
  • Contrast
  • Functional neuroimaging
  • Nanoparticles
  • Neuroimaging
  • Superparamagnetic iron oxide

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology


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