Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography

Hrebesh M. Subhash; Viviana Davila; Hai Sun; Anh T. Nguyen-Huynh; Alfred L. Nuttall; Ruikang K. Wang

doi:10.1117/12.874182

Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography

Hrebesh M. Subhash, Viviana Davila, Hai Sun, Anh T. Nguyen-Huynh, Alfred L. Nuttall, Ruikang K. Wang

Otolaryngology

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Studying the inner ear microstructures and microvascular dynamics is extremely important to understand the cochlear function and to further advance the diagnosis, prevention and treatment of many otologic disorders. There is considerable interest in developing new methods for in vivo imaging of the complex anatomy of the mammalian cochlea and the micro vascular perfusion within it for both clinical as well as fundamental studies. In this study, we explored the feasibility of high-speed spectral domain optical coherence tomography (SD-OCT) and ultra-high sensitive optical microangiography (UHS-OMAG) for volumetric in vivo imaging of intracochlear microstructures and microvascular perfusion in mice, respectively.

Original language	English (US)
Title of host publication	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
DOIs	https://doi.org/10.1117/12.874182
State	Published - 2011
Event	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV - San Francisco, CA, United States Duration: Jan 24 2011 → Jan 26 2011

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	7889
ISSN (Print)	1605-7422

Other

Other	Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV
Country/Territory	United States
City	San Francisco, CA
Period	1/24/11 → 1/26/11

Keywords

Optical coherence tomography
biomedical optical imaging
blood flow measurement
image processing
optical interferometry
optical microangiography
spectral interferometry

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

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Subhash, H. M., Davila, V., Sun, H., Nguyen-Huynh, A. T., Nuttall, A. L., & Wang, R. K. (2011). Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV Article 78892V (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7889). https://doi.org/10.1117/12.874182

Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography. / Subhash, Hrebesh M.; Davila, Viviana; Sun, Hai et al.
Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV. 2011. 78892V (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7889).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Subhash, HM, Davila, V, Sun, H, Nguyen-Huynh, AT, Nuttall, AL & Wang, RK 2011, Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography. in Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV., 78892V, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 7889, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV, San Francisco, CA, United States, 1/24/11. https://doi.org/10.1117/12.874182

Subhash HM, Davila V, Sun H, Nguyen-Huynh AT, Nuttall AL, Wang RK. Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography. In Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV. 2011. 78892V. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). doi: 10.1117/12.874182

Subhash, Hrebesh M. ; Davila, Viviana ; Sun, Hai et al. / Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography. Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XV. 2011. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography

Abstract

Publication series

Other

Keywords

ASJC Scopus subject areas

Access to Document

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Cite this