TY - GEN
T1 - Volumetric intracardiac imaging using a fully integrated CMUT ring array
T2 - 2011 IEEE International Ultrasonics Symposium, IUS 2011
AU - Moini, Azadeh
AU - Nikoozadeh, Amin
AU - Oralkan, Ömer
AU - Choe, Jung Woo
AU - Sarioglu, A. Fatih
AU - Stephens, Douglas N.
AU - De La Rama, Alan
AU - Chen, Peter
AU - Chalek, Carl
AU - Dentinger, Aaron
AU - Wildes, Douglas
AU - Smith, Lowell S.
AU - Thomenius, Kai
AU - Shivkumar, Kalyanam
AU - Mahajan, Aman
AU - O'Donnell, Matthew
AU - Sahn, David J.
AU - Khuri-Yakub, Pierre T.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2011
Y1 - 2011
N2 - Atrial fibrillation, the most common type of cardiac arrhythmia, now affects more than 2.2 million adults in the US alone. Currently, electrophysiological interventions are performed under fluoroscopy guidance, a procedure that introduces harmful ionizing radiation without providing adequate soft-tissue resolution. Intracardiac echocardiography (ICE) provides real-time, high-resolution anatomical information, reduces fluoroscopy time, and enhances procedural success. We have previously developed a forward-looking, volumetric ICE catheter using a ring-shaped, 64-element capacitive micromachined ultrasonic transducer (CMUT) array with a 10MHz center frequency. The Ring array was flip-chip bonded to a flexible PCB along with 8 identical custom ASICs providing a total of 64 dedicated preamplifiers. The flex was then reshaped for integration with the catheter shaft. In the second-generation catheter, 72 micro-coaxial cables (reduced from 100) are terminated on a newly designed flex to provide the connection between the array electronics and the imaging system. The reduced number of cables enhances the catheter's steerability. Furthermore, the new flex allows grounding of the top CMUT electrode through proper level-shifting of the ASIC supplies without additional circuitry. This feature enables complete ground shielding of the catheter, which improves its noise susceptibility and is an important safety measure for its clinical use. Beyond real-time, forward-looking imaging capability, the Ring catheter provides a continuous central lumen, enabling convenient delivery of other devices such as HIFU transducers, RF ablation catheters, etc. Using a PC-based imaging platform from Verasonics and a commercial Vivid7 imaging system from GE, we have demonstrated the in vivo, volumetric, real-time imaging capability of the finalized Ring catheter in a pig heart.
AB - Atrial fibrillation, the most common type of cardiac arrhythmia, now affects more than 2.2 million adults in the US alone. Currently, electrophysiological interventions are performed under fluoroscopy guidance, a procedure that introduces harmful ionizing radiation without providing adequate soft-tissue resolution. Intracardiac echocardiography (ICE) provides real-time, high-resolution anatomical information, reduces fluoroscopy time, and enhances procedural success. We have previously developed a forward-looking, volumetric ICE catheter using a ring-shaped, 64-element capacitive micromachined ultrasonic transducer (CMUT) array with a 10MHz center frequency. The Ring array was flip-chip bonded to a flexible PCB along with 8 identical custom ASICs providing a total of 64 dedicated preamplifiers. The flex was then reshaped for integration with the catheter shaft. In the second-generation catheter, 72 micro-coaxial cables (reduced from 100) are terminated on a newly designed flex to provide the connection between the array electronics and the imaging system. The reduced number of cables enhances the catheter's steerability. Furthermore, the new flex allows grounding of the top CMUT electrode through proper level-shifting of the ASIC supplies without additional circuitry. This feature enables complete ground shielding of the catheter, which improves its noise susceptibility and is an important safety measure for its clinical use. Beyond real-time, forward-looking imaging capability, the Ring catheter provides a continuous central lumen, enabling convenient delivery of other devices such as HIFU transducers, RF ablation catheters, etc. Using a PC-based imaging platform from Verasonics and a commercial Vivid7 imaging system from GE, we have demonstrated the in vivo, volumetric, real-time imaging capability of the finalized Ring catheter in a pig heart.
KW - CMUT
KW - capacitive micromachined ultrasonic transducer
KW - electrophysiology
KW - forward-looking
KW - intracardiac echo
KW - real-time
KW - ultrasound
KW - volumetric
UR - http://www.scopus.com/inward/record.url?scp=84869036702&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84869036702&partnerID=8YFLogxK
U2 - 10.1109/ULTSYM.2011.0168
DO - 10.1109/ULTSYM.2011.0168
M3 - Conference contribution
AN - SCOPUS:84869036702
SN - 9781457712531
T3 - IEEE International Ultrasonics Symposium, IUS
SP - 692
EP - 695
BT - 2011 IEEE International Ultrasonics Symposium, IUS 2011
Y2 - 18 October 2011 through 21 October 2011
ER -