Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction

Ulrike Attenberger; Ciprian Catana; Hersh Chandarana; Onofrio A. Catalano; Kent Friedman; Stefan A. Schonberg; James Thrall; Marco Salvatore; Bruce R. Rosen; Alexander R. Guimaraes

doi:10.1007/s00261-015-0455-3

Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction

Ulrike Attenberger, Ciprian Catana, Hersh Chandarana, Onofrio A. Catalano, Kent Friedman, Stefan A. Schonberg, James Thrall, Marco Salvatore, Bruce R. Rosen, Alexander R. Guimaraes

Diagnostic Radiology

Research output: Contribution to journal › Review article › peer-review

26 Scopus citations

Abstract

Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.

Original language	English (US)
Pages (from-to)	1374-1386
Number of pages	13
Journal	Abdominal Imaging
Volume	40
Issue number	6
DOIs	https://doi.org/10.1007/s00261-015-0455-3
State	Published - Aug 12 2015

Keywords

Attenuation correction
PET/MRI
Pitfalls

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging
Gastroenterology
Urology

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10.1007/s00261-015-0455-3

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Attenberger, U., Catana, C., Chandarana, H., Catalano, O. A., Friedman, K., Schonberg, S. A., Thrall, J., Salvatore, M., Rosen, B. R., & Guimaraes, A. R. (2015). Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction. Abdominal Imaging, 40(6), 1374-1386. https://doi.org/10.1007/s00261-015-0455-3

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abstract = "Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.",

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author = "Ulrike Attenberger and Ciprian Catana and Hersh Chandarana and Catalano, {Onofrio A.} and Kent Friedman and Schonberg, {Stefan A.} and James Thrall and Marco Salvatore and Rosen, {Bruce R.} and Guimaraes, {Alexander R.}",

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year = "2015",

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doi = "10.1007/s00261-015-0455-3",

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AU - Attenberger, Ulrike

AU - Catana, Ciprian

AU - Chandarana, Hersh

AU - Catalano, Onofrio A.

AU - Friedman, Kent

AU - Schonberg, Stefan A.

AU - Thrall, James

AU - Salvatore, Marco

AU - Rosen, Bruce R.

AU - Guimaraes, Alexander R.

PY - 2015/8/12

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N2 - Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.

AB - Simultaneous data collection for positron emission tomography and magnetic resonance imaging (PET/MR) is now a reality. While the full benefits of concurrently acquiring PET and MR data and the potential added clinical value are still being evaluated, initial studies have identified several important potential pitfalls in the interpretation of fluorodeoxyglucose (FDG) PET/MRI in oncologic whole-body imaging, the majority of which being related to the errors in the attenuation maps created from the MR data. The purpose of this article was to present such pitfalls and artifacts using case examples, describe their etiology, and discuss strategies to overcome them. Using a case-based approach, we will illustrate artifacts related to (1) Inaccurate bone tissue segmentation; (2) Inaccurate air cavities segmentation; (3) Motion-induced misregistration; (4) RF coils in the PET field of view; (5) B0 field inhomogeneity; (6) B1 field inhomogeneity; (7) Metallic implants; (8) MR contrast agents.

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Whole-body FDG PET-MR oncologic imaging: pitfalls in clinical interpretation related to inaccurate MR-based attenuation correction

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Keywords

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