Widespread retinal hemorrhages after retinopathy of prematurity screening with scleral depression

Anne K. Jensen, Brian J. Forbes, Lorri B. Wilson, Debra Prieto, Gil Binenbaum

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


We report a case of extensive bilateral intraretinal hemorrhages in a premature infant with active retinopathy of prematurity (ROP) after an examination with scleral depression. In the only other previously reported case, the retinal hemorrhages were limited to the posterior pole of an eye with preexisting vitreous hemorrhage, and the child had a history of severe necrotizing enterocolitis that required surgery. Investigators have hypothesized that the combination of ocular manipulation, abrupt intraocular pressure change, and fragile immature retinal vasculature with poor autoregulation may contribute to the pathogenesis of retinal hemorrhages. Physicians performing ROP examinations should be aware of this possibility and judiciously use scleral depression; however, examination-induced retinal hemorrhages in children have never been reported in the absence of active ROP.

Original languageEnglish (US)
Pages (from-to)609-611
Number of pages3
JournalJournal of AAPOS
Issue number6
StatePublished - Dec 2011
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Ophthalmology


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