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Gordon Mills

Director of Precision Oncology

Calculated based on number of publications stored in Pure and citations from Scopus
1976 …2024

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  • 2018

    The Integrated Genomic Landscape of Thymic Epithelial Tumors

    The Cancer Genome Atlas Network, Feb 12 2018, In: Cancer Cell. 33, 2, p. 244-258.e10

    Research output: Contribution to journal › Article › peer-review

    Open Access
    250 Scopus citations

  • The tumour suppressor OPCML promotes AXL inactivation by the phosphatase PTPRG in ovarian cancer

    Antony, J., Zanini, E., Kelly, Z., Tan, T. Z., Karali, E., Alomary, M., Jung, Y., Nixon, K., Cunnea, P., Fotopoulou, C., Paterson, A., Roy-Nawathe, S., Mills, G. B., Huang, R. Y. J., Thiery, J. P., Gabra, H. & Recchi, C., Aug 2018, In: EMBO Reports. 19, 8, e45670.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Scopus citations

  • β-catenin/TCF activity regulates IGF-1R tyrosine kinase inhibitor sensitivity in colon cancer

    Lee, H., Kim, N., Yoo, Y. J., Kim, H., Jeong, E., Choi, S. G., Moon, S. U., Oh, S. H., Mills, G. B., Yoon, S. & Kim, W. Y., Oct 4 2018, In: Oncogene. 37, 40, p. 5466-5475 10 p.

    Research output: Contribution to journal › Article › peer-review

    13 Scopus citations
  • 2017

    A Comprehensive Patient-Derived Xenograft Collection Representing the Heterogeneity of Melanoma

    Krepler, C., Sproesser, K., Brafford, P., Beqiri, M., Garman, B., Xiao, M., Shannan, B., Watters, A., Perego, M., Zhang, G., Vultur, A., Yin, X., Liu, Q., Anastopoulos, I. N., Wubbenhorst, B., Wilson, M. A., Xu, W., Karakousis, G., Feldman, M., Xu, X., & 34 othersAmaravadi, R., Gangadhar, T. C., Elder, D. E., Haydu, L. E., Wargo, J. A., Davies, M. A., Lu, Y., Mills, G. B., Frederick, D. T., Barzily-Rokni, M., Flaherty, K. T., Hoon, D. S., Guarino, M., Bennett, J. J., Ryan, R. W., Petrelli, N. J., Shields, C. L., Terai, M., Sato, T., Aplin, A. E., Roesch, A., Darr, D., Angus, S., Kumar, R., Halilovic, E., Caponigro, G., Jeay, S., Wuerthner, J., Walter, A., Ocker, M., Boxer, M. B., Schuchter, L., Nathanson, K. L. & Herlyn, M., Nov 14 2017, In: Cell Reports. 21, 7, p. 1953-1967 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    102 Scopus citations

  • Active disclosure of secondary germline findings to deceased research participants' personal representatives: Process and outcomes

    Daniels, M., Wathoo, C., Brusco, L., Lu, K. H., Shaw, K., Dumbrava, E. E. I., Arun, B., Strong, L., Litton, J. K., Eterovic, K., Aytac, U., Mendelsohn, J., Mills, G. B., Chen, K. & Meric-Bernstam, F., 2017, In: JCO Precision Oncology. 2017, 1, p. 1-5 5 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    4 Scopus citations

  • A feasibility study of neoadjuvant talazoparib for operable breast cancer patients with a germline BRCA mutation demonstrates marked activity

    Litton, J. K., Scoggins, M., Ramirez, D. L., Murthy, R. K., Whitman, G. J., Hess, K. R., Adrada, B. E., Moulder, S. L., Barcenas, C. H., Valero, V., Schwartz Gomez, J., Mittendorf, E. A., Thompson, A., Helgason, T., Mills, G. B., Piwnica-Worms, H. & Arun, B. K., 2017, In: npj Breast Cancer. 3, 1, 49.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • A feasibility study of returning clinically actionable somatic genomic alterations identified in a research laboratory

    Arango, N. P., Brusco, L., Shaw, K. R. M., Chen, K., Eterovic, A. K., Holla, V., Johnson, A., Litzenburger, B., Khotskaya, Y. B., Sanchez, N., Bailey, A., Zheng, X., Horombe, C., Kopetz, S., Farhangfar, C. J., Routbort, M., Broaddus, R., Bernstam, E. V., Mendelsohn, J., Mills, G. B., & 1 othersMeric-Bernstam, F., 2017, In: Oncotarget. 8, 26, p. 41806-41814 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • A murine preclinical syngeneic transplantation model for breast cancer precision medicine

    Federico, L., Chong, Z., Zhang, D., McGrail, D. J., Zhao, W., Jeong, K. J., Vellano, C. P., Ju, Z., Gagea, M., Liu, S., Mitra, S., Dennison, J. B., Lorenzi, P. L., Cardnell, R., Diao, L., Wang, J., Lu, Y., Byers, L. A., Perou, C. M., Lin, S. Y., & 1 othersMills, G. B., Apr 2017, In: Science Advances. 3, 4, e1600957.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    11 Scopus citations

  • A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations

    Zhang, Y., Kwok-Shing Ng, P., Kucherlapati, M., Chen, F., Liu, Y., Tsang, Y. H., de Velasco, G., Jeong, K. J., Akbani, R., Hadjipanayis, A., Pantazi, A., Bristow, C. A., Lee, E., Mahadeshwar, H. S., Tang, J., Zhang, J., Yang, L., Seth, S., Lee, S., Ren, X., & 22 othersSong, X., Sun, H., Seidman, J., Luquette, L. J., Xi, R., Chin, L., Protopopov, A., Westbrook, T. F., Shelley, C. S., Choueiri, T. K., Ittmann, M., Van Waes, C., Weinstein, J. N., Liang, H., Henske, E. P., Godwin, A. K., Park, P. J., Kucherlapati, R., Scott, K. L., Mills, G. B., Kwiatkowski, D. J. & Creighton, C. J., Jun 12 2017, In: Cancer Cell. 31, 6, p. 820-832.e3

    Research output: Contribution to journal › Article › peer-review

    Open Access
    380 Scopus citations

  • A patient-derived-xenograft platform to study BRCA-deficient ovarian cancers

    George, E., Kim, H., Krepler, C., Wenz, B., Makvandi, M., Tanyi, J. L., Brown, E., Zhang, R., Brafford, P., Jean, S., Mach, R. H., Lu, Y., Mills, G. B., Herlyn, M., Morgan, M., Zhang, X., Soslow, R., Drapkin, R., Johnson, N., Zheng, Y., & 3 othersCotsarelis, G., Nathanson, K. L. & Simpkins, F., Jan 12 2017, In: JCI Insight. 2, 1, e89760.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    50 Scopus citations

  • A population of heterogeneous breast cancer patient-derived xenografts demonstrate broad activity of PARP inhibitor in BRCA1/2 wild-type tumors

    Evans, K. W., Yuca, E., Akcakanat, A., Scott, S. M., Arango, N. P., Zheng, X., Chen, K., Tapia, C., Tarco, E., Eterovic, A. K., Black, D. M., Litton, J. K., Yap, T. A., Tripathy, D., Mills, G. B. & Meric-Bernstam, F., Nov 1 2017, In: Clinical Cancer Research. 23, 21, p. 6468-6477 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • ATG5 mediates a positive feedback loop between wnt signaling and autophagy in melanoma

    Ndoye, A., Budina-Kolomets, A., Kugel, C. H., Webster, M. R., Kaur, A., Behera, R., Rebecca, V. W., Li, L., Brafford, P. A., Liu, Q., Gopal, Y. N. V., Davies, M. A., Mills, G. B., Xu, X., Wu, H., Herlyn, M., Nicastri, M. C., Winkle, J. D., Soengas, M. S., Amaravadi, R. K., & 2 othersMurphy, M. E. & Weeraratna, A. T., Nov 1 2017, In: Cancer Research. 77, 21, p. 5873-5885 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • A unified approach to targeting the lysosome’s degradative and growth signaling roles

    Rebecca, V. W., Nicastri, M. C., McLaughlin, N., Fennelly, C., McAfee, Q., Ronghe, A., Nofal, M., Lim, C. Y., Witze, E., Chude, C. I., Zhang, G., Alicea, G. M., Piao, S., Murugan, S., Ojha, R., Levi, S. M., Wei, Z., Barber-Rotenberg, J. S., Murphy, M. E., Mills, G. B., & 12 othersLu, Y., Rabinowitz, J., Marmorstein, R., Liu, Q., Liu, S., Xu, X., Herlyn, M., Zoncu, R., Brady, D. C., Speicher, D. W., Winkler, J. D. & Amaravadi, R. K., Nov 2017, In: Cancer discovery. 7, 11, p. 1266-1283 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    146 Scopus citations

  • Characteristics of percutaneous core biopsies adequate for next generation genomic sequencing

    Sabir, S. H., Krishnamurthy, S., Gupta, S., Mills, G. B., Wei, W., Cortes, A. C., Mills Shaw, K. R., Luthra, R. & Wallace, M. J., Dec 2017, In: PloS one. 12, 12, e0189651.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

    Li, J., Zhao, W., Akbani, R., Liu, W., Ju, Z., Ling, S., Vellano, C. P., Roebuck, P., Yu, Q., Eterovic, A. K., Byers, L. A., Davies, M. A., Deng, W., Gopal, Y. N. V., Chen, G., von Euw, E. M., Slamon, D., Conklin, D., Heymach, J. V., Gazdar, A. F., & 5 othersMinna, J. D., Myers, J. N., Lu, Y., Mills, G. B. & Liang, H., Feb 13 2017, In: Cancer Cell. 31, 2, p. 225-239 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    152 Scopus citations

  • Chk1 inhibition potentiates the therapeutic efficacy of PARP inhibitor BMN673 in gastric cancer

    Yin, Y., Shen, Q., Zhang, P., Tao, R., Chang, W., Li, R., Xie, G., Liu, W., Zhang, L., Kapoor, P., Song, S., Ajani, J., Mills, G. B., Chen, J., Tao, K. & Peng, G., 2017, In: American Journal of Cancer Research. 7, 3, p. 473-483 11 p.

    Research output: Contribution to journal › Article › peer-review

    40 Scopus citations

  • Clinical use of precision oncology decision support

    Johnson, A., Khotskaya, Y. B., Brusco, L., Zeng, J., Holla, V., Bailey, A. M., Litzenburger, B. C., S.Sánchez, N., Shufean, M. A., Piha-Paul, S., Subbiah, V., Hong, D., Routbort, M., Broaddus, R., Mills Shaw, K. R., Mills, G. B., Mendelsohn, J. & Meric-Bernstam, F., 2017, In: JCO Precision Oncology. 2017, 1, p. 1-12 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    28 Scopus citations

  • Comparison of Breast Cancer Molecular Features and Survival by African and European Ancestry in The Cancer Genome Atlas

    Huo, D., Hu, H., Rhie, S. K., Gamazon, E. R., Cherniack, A. D., Liu, J., Yoshimatsu, T. F., Pitt, J. J., Hoadley, K. A., Troester, M., Ru, Y., Lichtenberg, T., Sturtz, L. A., Shelley, C. S., Benz, C. C., Mills, G. B., Laird, P. W., Shriver, C. D., Perou, C. M. & Olopade, O. I., Dec 1 2017, In: JAMA Oncology. 3, 12, p. 1654-1662 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    179 Scopus citations

  • Comprehensive and Integrated Genomic Characterization of Adult Soft Tissue Sarcomas

    The Cancer Genome Atlas Research Network, Nov 2 2017, In: Cell. 171, 4, p. 950-965.e28

    Research output: Contribution to journal › Article › peer-review

    Open Access
    622 Scopus citations

  • Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma

    The Cancer Genome Atlas Research Network, Jun 15 2017, In: Cell. 169, 7, p. 1327-1341.e23

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1427 Scopus citations

  • Comprehensive Molecular Characterization of Muscle-Invasive Bladder Cancer

    Robertson, A. G., Kim, J., Al-Ahmadie, H., Bellmunt, J., Guo, G., Cherniack, A. D., Hinoue, T., Laird, P. W., Hoadley, K. A., Akbani, R., Castro, M. A. A., Gibb, E. A., Kanchi, R. S., Gordenin, D. A., Shukla, S. A., Sanchez-Vega, F., Hansel, D. E., Czerniak, B. A., Reuter, V. E., Su, X., & 153 othersde Sa Carvalho, B., Chagas, V. S., Mungall, K. L., Sadeghi, S., Pedamallu, C. S., Lu, Y., Klimczak, L. J., Zhang, J., Choo, C., Ojesina, A. I., Bullman, S., Leraas, K. M., Lichtenberg, T. M., Wu, C. J., Schultz, N., Getz, G., Meyerson, M., Mills, G. B., McConkey, D. J., Albert, M., Alexopoulou, I., Ally, A., Antic, T., Aron, M., Balasundaram, M., Bartlett, J., Baylin, S. B., Beaver, A., Birol, I., Boice, L., Bootwalla, M. S., Bowen, J., Bowlby, R., Brooks, D., Broom, B. M., Bshara, W., Burks, E., Cárcano, F. M., Carlsen, R., Carvalho, A. L., Castle, E. P., Castro, P., Catto, J. W., Chesla, D. W., Chuah, E., Chudamani, S., Cortessis, V. K., Cottingham, S. L., Crain, D., Curley, E., Daneshmand, S., Demchok, J. A., Dhalla, N., Djaladat, H., Eckman, J., Egea, S. C., Engel, J., Felau, I., Ferguson, M. L., Gardner, J., Gastier-Foster, J. M., Gerken, M., Gomez-Fernandez, C. R., Harr, J., Hartmann, A., Herbert, L. M., Ho, T. H., Holt, R. A., Hutter, C. M., Jones, S. J. M., Jorda, M., Kahnoski, R. J., Kasaian, K., Kwiatkowski, D. J., Lai, P. H., Lane, B. R., Lerner, S. P., Liu, J., Lolla, L., Lotan, Y., Lucchesi, F. R., Ma, Y., Machado, R. D., Maglinte, D. T., Mallery, D., Marra, M. A., Martin, S. E., Mayo, M., Meraney, A., Moinzadeh, A., Moore, R. A., Mora Pinero, E. M., Morris, S., Morrison, C., Mungall, A. J., Myers, J. B., Naresh, R., O'Donnell, P. H., Parekh, D. J., Parfitt, J., Paulauskis, J. D., Sekhar Pedamallu, C., Penny, R. J., Pihl, T., Porten, S., Quintero-Aguilo, M. E., Ramirez, N. C., Rathmell, W. K., Rieger-Christ, K., Saller, C., Salner, A., Sandusky, G., Scapulatempo-Neto, C., Schein, J. E., Schuckman, A. K., Shelton, C., Shelton, T., Simko, J., Singh, P., Sipahimalani, P., Smith, N. D., Sofia, H. J., Sorcini, A., Stanton, M. L., Steinberg, G. D., Stoehr, R., Su, X., Sullivan, T., Sun, Q., Tam, A., Tarnuzzer, R., Tarvin, K., Taubert, H., Thiessen, N., Thorne, L., Tse, K., Tucker, K., Van Den Berg, D. J., van Kessel, K. E., Wach, S., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wise, L., Wong, T., Wu, Y., Yang, L., Zach, L. A., Zenklusen, J. C., Zhang, J., Zmuda, E. & Zwarthoff, E. C., Oct 19 2017, In: Cell. 171, 3, p. 540-556.e25

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1465 Scopus citations

  • Comprehensive Molecular Characterization of Pheochromocytoma and Paraganglioma

    Fishbein, L., Leshchiner, I., Walter, V., Danilova, L., Robertson, A. G., Johnson, A. R., Lichtenberg, T. M., Murray, B. A., Ghayee, H. K., Else, T., Ling, S., Jefferys, S. R., de Cubas, A. A., Wenz, B., Korpershoek, E., Amelio, A. L., Makowski, L., Rathmell, W. K., Gimenez-Roqueplo, A. P., Giordano, T. J., & 187 othersAsa, S. L., Tischler, A. S., Akbani, R., Ally, A., Amar, L., Arachchi, H., Auchus, R. J., Auman, J. T., Baertsch, R., Balasundaram, M., Balu, S., Bartsch, D. K., Baudin, E., Bauer, T., Beaver, A., Benz, C., Beroukhim, R., Beuschlein, F., Bodenheimer, T., Boice, L., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Carter, S., Cassol, C. A., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cope, L., Crain, D., Curley, E., de Krijger, R. R., Demchok, J. A., Deutschbein, T., Dhalla, N., Dimmock, D., Dinjens, W. N. M., Eng, C., Eschbacher, J., Fassnacht, M., Felau, I., Feldman, M., Ferguson, M. L., Fiddes, I., Frazer, S., Gabriel, S. B., Gardner, J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Geurts, J., Goldman, M., Graim, K., Gupta, M., Haan, D., Hahner, S., Hantel, C., Haussler, D., Hayes, D. N., Heiman, D. I., Hoadley, K. A., Holt, R. A., Hoyle, A. P., Huang, M., Hunt, B., Hutter, C. M., Jones, S. J. M., Jones, C. D., Kasaian, K., Kebebew, E., Kim, J., Kimes, P., Knijnenburg, T., Lander, E., Lawrence, M. S., Lechan, R., Lee, D., Leraas, K. M., Lerario, A., Lin, P., Liu, J., LiVolsi, V. A., Lolla, L., Lotan, Y., Lu, Y., Ma, Y., Maison, N., Mallery, D., Mannelli, M., Marquard, J., Marra, M. A., Matthew, T., Mayo, M., Méatchi, T., Meng, S., Merino, M. J., Mete, O., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Morozova, O., Morris, S., Mose, L. E., Mungall, A. J., Naresh, R., Nathanson, K. L., Newton, Y., Ng, S., Ni, Y., Noble, M. S., Nwariaku, F., Pacak, K., Parker, J. S., Paul, E., Penny, R., Perou, C. M., Perou, A. H., Pihl, T., Powers, J., Rabaglia, J., Radenbaugh, A., Ramirez, N. C., Rao, A., Riester, A., Roach, J., Sadeghi, S., Saksena, G., Salama, S., Saller, C., Sandusky, G., Sbiera, S., Schein, J. E., Schumacher, S. E., Shelton, C., Shelton, T., Sheth, M., Shi, Y., Shih, J., Shmulevich, I., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Sokolov, A., Soloway, M. G., Sougnez, C., Stuart, J., Sun, C., Swatloski, T., Tam, A., Tan, D., Tarnuzzer, R., Tarvin, K., Thiessen, N., Thorne, L. B., Timmers, H. J., Tse, K., Uzunangelov, V., van Berkel, A., Veluvolu, U., Vicha, A., Voet, D., Waldmann, J., Wan, Y., Wang, Z., Wang, T. S., Weaver, J., Weinstein, J. N., Weismann, D., Wilkerson, M. D., Wise, L., Wong, T., Wong, C., Wu, Y., Yang, L., Zelinka, T., Zenklusen, J. C., Zhang, J., Zhang, W., Zhu, J., Zinzindohoué, F. & Zmuda, E., Feb 13 2017, In: Cancer Cell. 31, 2, p. 181-193 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    498 Scopus citations

  • Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

    Hill, S. M., Nesser, N. K., Johnson-Camacho, K., Jeffress, M., Johnson, A., Boniface, C., Spencer, S. E. F., Lu, Y., Heiser, L. M., Lawrence, Y., Pande, N. T., Korkola, J. E., Gray, J. W., Mills, G. B., Mukherjee, S. & Spellman, P. T., Jan 25 2017, In: Cell Systems. 4, 1, p. 73-83.e10

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • CTNNB1 (beta-catenin) mutation identifies low grade, early stage endometrial cancer patients at increased risk of recurrence

    Kurnit, K. C., Kim, G. N., Fellman, B. M., Urbauer, D. L., Mills, G. B., Zhang, W. & Broaddus, R. R., Jul 1 2017, In: Modern Pathology. 30, 7, p. 1032-1041 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    209 Scopus citations

  • Development and validation of an ultradeep next-generation sequencing assay for testing of plasma cell-free DNA from patients with advanced cancer

    Janku, F., Zhang, S., Waters, J., Liu, L., Huang, H. J., Subbiah, V., Hong, D. S., Karp, D. D., Fu, S., Cai, X., Ramzanali, N. M., Madwani, K., Cabrilo, G., Andrews, D. L., Zhao, Y., Javle, M., Kopetz, E. S., Luthra, R., Kim, H. J., Gnerre, S., & 11 othersSatya, R. V., Chuang, H. Y., Kruglyak, K. M., Toung, J., Zhao, C., Shen, R., Heymach, J. V., Meric-Bernstam, F., Mills, G. B., Fan, J. B. & Salathia, N. S., Sep 15 2017, In: Clinical Cancer Research. 23, 18, p. 5648-5656 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    44 Scopus citations

  • Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer

    Lu, H., Villafane, N., Dogruluk, T., Grzeskowiak, C. L., Kong, K., Tsang, Y. H., Zagorodna, O., Pantazi, A., Yang, L., Neill, N. J., Kim, Y. W., Creighton, C. J., Verhaak, R. G., Mills, G. B., Park, P. J., Kucherlapati, R. & Scott, K. L., Jul 1 2017, In: Cancer Research. 77, 13, p. 3502-3512 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Epigenetic regulation of KPC1 ubiquitin ligase affects the NF-κB pathway in melanoma

    Iida, Y., Ciechanover, A., Marzese, D. M., Hata, K., Bustos, M., Ono, S., Wang, J., Salomon, M. P., Tran, K., Lam, S., Hsu, S., Nelson, N., Kravtsova-Ivantsiv, Y., Mills, G. B., Davies, M. A. & Hoon, D. S. B., Aug 15 2017, In: Clinical Cancer Research. 23, 16, p. 4831-4842 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    27 Scopus citations

  • Establishment of patient-derived tumor xenograft models of epithelial ovarian cancer for preclinical evaluation of novel therapeutics

    Liu, J. F., Palakurthi, S., Zeng, Q., Zhou, S., Ivanova, E., Huang, W., Zervantonakis, I. K., Selfors, L. M., Shen, Y., Pritchard, C. C., Zheng, M., Adleff, V., Papp, E., Piao, H., Novak, M., Fotheringham, S., Wulf, G. M., English, J., Kirschmeier, P. T., Velculescu, V. E., & 6 othersPaweletz, C., Mills, G. B., Livingston, D. M., Brugge, J. S., Matulonis, U. A. & Drapkin, R., Mar 1 2017, In: Clinical Cancer Research. 23, 5, p. 1263-1273 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    91 Scopus citations

  • Explore, visualize, and analyze functional cancer proteomic data using the cancer proteome atlas

    Li, J., Akbani, R., Zhao, W., Lu, Y., Weinstein, J. N., Mills, G. B. & Liang, H., Nov 1 2017, In: Cancer Research. 77, 21, p. e51-e54

    Research output: Contribution to journal › Article › peer-review

    Open Access
    75 Scopus citations

  • Genomic analysis of exceptional responder to regorafenib in treatment-refractory metastatic rectal cancer: A case report and review of the literature

    Korphaisarn, K., Loree, J. M., Nguyen, V., Coulson, R., Holla, V., Litzenburger, B. C., Chen, K., Mills, G. B., Maru, D. M., Meric-Bernstan, F., Shaw, K. R. M. & Kopetz, S., 2017, In: Oncotarget. 8, 34, p. 57882-57888 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm

    McGrail, D. J., Lin, C. C. J., Garnett, J., Liu, Q., Mo, W., Dai, H., Lu, Y., Yu, Q., Ju, Z., Yin, J., Vellano, C. P., Hennessy, B., Mills, G. B. & Lin, S. Y., Dec 1 2017, In: npj Systems Biology and Applications. 3, 1, 8.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • Integrated genomic and molecular characterization of cervical cancer

    The Cancer Genome Atlas Research Network, Mar 16 2017, In: Nature. 543, 7645, p. 378-384 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    984 Scopus citations

  • Integrated genomic characterization of oesophageal carcinoma

    The Cancer Genome Atlas Research Network, Jan 12 2017, In: Nature. 541, 7636, p. 169-174 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1193 Scopus citations

  • Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma

    Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., Gabriel, S. B., Meyerson, M., Cibulskis, C., Fei, S. S., Hinoue, T., Shen, H., Laird, P. W., Ling, S., Lu, Y., Mills, G. B., & 251 othersAkbani, R., Loher, P., Londin, E. R., Rigoutsos, I., Telonis, A. G., Gibb, E. A., Goldenberg, A., Mezlini, A. M., Hoadley, K. A., Collisson, E., Lander, E., Murray, B. A., Hess, J., Rosenberg, M., Bergelson, L., Zhang, H., Cho, J., Tiao, G., Kim, J., Livitz, D., Leshchiner, I., Reardon, B., Van Allen, E., Kamburov, A., Beroukhim, R., Saksena, G., Schumacher, S. E., Noble, M. S., Heiman, D. I., Gehlenborg, N., Kim, J., Lawrence, M. S., Adsay, V., Petersen, G., Klimstra, D., Bardeesy, N., Leiserson, M. D. M., Bowlby, R., Kasaian, K., Birol, I., Mungall, K. L., Sadeghi, S., Weinstein, J. N., Spellman, P. T., Liu, Y., Amundadottir, L. T., Tepper, J., Singhi, A. D., Dhir, R., Paul, D., Smyrk, T., Zhang, L., Kim, P., Bowen, J., Frick, J., Gastier-Foster, J. M., Gerken, M., Lau, K., Leraas, K. M., Lichtenberg, T. M., Ramirez, N. C., Renkel, J., Sherman, M., Wise, L., Yena, P., Zmuda, E., Shih, J., Ally, A., Balasundaram, M., Carlsen, R., Chu, A., Chuah, E., Clarke, A., Dhalla, N., Holt, R. A., Jones, S. J. M., Lee, D., Ma, Y., Marra, M. A., Mayo, M., Moore, R. A., Mungall, A. J., Schein, J. E., Sipahimalani, P., Tam, A., Thiessen, N., Tse, K., Wong, T., Brooks, D., Auman, J. T., Balu, S., Bodenheimer, T., Hayes, D. N., Hoyle, A. P., Jefferys, S. R., Jones, C. D., Meng, S., Mieczkowski, P. A., Mose, L. E., Perou, C. M., Perou, A. H., Roach, J., Shi, Y., Simons, J. V., Skelly, T., Soloway, M. G., Tan, D., Veluvolu, U., Parker, J. S., Wilkerson, M. D., Korkut, A., Senbabaoglu, Y., Burch, P., McWilliams, R., Chaffee, K., Oberg, A., Zhang, W., Gingras, M. C., Wheeler, D. A., Xi, L., Albert, M., Bartlett, J., Sekhon, H., Stephen, Y., Howard, Z., Judy, M., Breggia, A., Shroff, R. T., Chudamani, S., Liu, J., Lolla, L., Naresh, R., Pihl, T., Sun, Q., Wan, Y., Wu, Y., Jennifer, S., Roggin, K., Becker, K. F., Behera, M., Bennett, J., Boice, L., Burks, E., Carlotti Junior, C. G., Chabot, J., Pretti da Cunha Tirapelli, D., Sebastião dos Santos, J., Dubina, M., Eschbacher, J., Huang, M., Huelsenbeck-Dill, L., Jenkins, R., Karpov, A., Kemp, R., Lyadov, V., Maithel, S., Manikhas, G., Montgomery, E., Noushmehr, H., Osunkoya, A., Owonikoko, T., Paklina, O., Potapova, O., Ramalingam, S., Rathmell, W. K., Rieger-Christ, K., Saller, C., Setdikova, G., Shabunin, A., Sica, G., Su, T., Sullivan, T., Swanson, P., Tarvin, K., Tavobilov, M., Thorne, L. B., Urbanski, S., Voronina, O., Wang, T., Crain, D., Curley, E., Gardner, J., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, C., Shelton, T., Janssen, K. P., Bathe, O., Bahary, N., Slotta-Huspenina, J., Johns, A., Hibshoosh, H., Hwang, R. F., Sepulveda, A., Radenbaugh, A., Baylin, S. B., Berrios, M., Bootwalla, M. S., Holbrook, A., Lai, P. H., Maglinte, D. T., Mahurkar, S., Triche, T. J., Van Den Berg, D. J., Weisenberger, D. J., Chin, L., Kucherlapati, R., Kucherlapati, M., Pantazi, A., Park, P., Saksena, G., Voet, D., Lin, P., Frazer, S., Defreitas, T., Meier, S., Chin, L., Kwon, S. Y., Kim, Y. H., Park, S. J., Han, S. S., Kim, S. H., Kim, H., Furth, E., Tempero, M., Sander, C., Biankin, A., Chang, D., Bailey, P., Gill, A., Kench, J., Grimmond, S., Johns, A., Cancer Genome Initiative (APGI, A. P., Postier, R., Zuna, R., Sicotte, H., Demchok, J. A., Ferguson, M. L., Hutter, C. M., Mills Shaw, K. R., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zhang, J., Felau, I. & Zenklusen, J. C., Aug 14 2017, In: Cancer Cell. 32, 2, p. 185-203.e13

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1170 Scopus citations

  • Integrated Molecular Characterization of Uterine Carcinosarcoma

    Cherniack, A. D., Shen, H., Walter, V., Stewart, C., Murray, B. A., Bowlby, R., Hu, X., Ling, S., Soslow, R. A., Broaddus, R. R., Zuna, R. E., Robertson, G., Laird, P. W., Kucherlapati, R., Mills, G. B., Akbani, R., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., & 130 othersBaylin, S. B., Beroukhim, R., Bodenheimer, T., Bogomolniy, F., Boice, L., Bootwalla, M. S., Bowen, J., Broaddus, R., Brooks, D., Carlsen, R., Cho, J., Chuah, E., Chudamani, S., Cibulskis, K., Cline, M., Dao, F., David, M., Demchok, J. A., Dhalla, N., Dowdy, S., Felau, I., Ferguson, M. L., Frazer, S., Frick, J., Gabriel, S., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gupta, M., Haussler, D., Hayes, D. N., Heiman, D. I., Hess, J., Hoadley, K. A., Hoffmann, R., Holt, R. A., Hoyle, A. P., Huang, M., Hutter, C. M., Jefferys, S. R., Jones, S. J. M., Jones, C. D., Kanchi, R. S., Kandoth, C., Kasaian, K., Kerr, S., Kim, J., Lai, P. H., Lander, E., Lawrence, M. S., Lee, D., Leraas, K. M., Leshchiner, I., Levine, D. A., Lichtenberg, T. M., Lin, P., Liu, J., Liu, W., Liu, Y., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Marra, M. A., Mayo, M., Meng, S., Meyerson, M., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Mungall, K., Naresh, R., Noble, M. S., Olvera, N., Parker, J. S., Perou, C. M., Perou, A. H., Pihl, T., Radenbaugh, A. J., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Sadeghi, S., Saksena, G., Salvesen, H. B., Schein, J. E., Schumacher, S. E., Sheth, M., Shi, Y., Shih, J., Simons, J. V., Sipahimalani, P., Skelly, T., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tam, A., Tan, D., Tarnuzzer, R., Thiessen, N., Thorne, L. B., Tse, K., Tseng, J., Van Den Berg, D. J., Veluvolu, U., Verhaak, R. G. W., Voet, D., von Bismarck, A., Wan, Y., Wang, Z., Wang, C., Weinstein, J. N., Weisenberger, D. J., Wilkerson, M. D., Winterhoff, B., Wise, L., Wong, T., Wu, Y., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H., Zhang, W., Zhu, J. C., Zmuda, E. & Zhang, J., Mar 13 2017, In: Cancer Cell. 31, 3, p. 411-423 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    272 Scopus citations

  • Integrative Analysis Identifies Four Molecular and Clinical Subsets in Uveal Melanoma

    Robertson, A. G., Shih, J., Yau, C., Gibb, E. A., Oba, J., Mungall, K. L., Hess, J. M., Uzunangelov, V., Walter, V., Danilova, L., Lichtenberg, T. M., Kucherlapati, M., Kimes, P. K., Tang, M., Penson, A., Babur, O., Akbani, R., Bristow, C. A., Hoadley, K. A., Iype, L., & 150 othersChang, M. T., Abdel-Rahman, M. H., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Benz, C., Beroukhim, R., Birol, I., Bodenheimer, T., Bowen, J., Bowlby, R., Brooks, D., Carlsen, R., Cebulla, C. M., Cherniack, A. D., Chin, L., Cho, J., Chuah, E., Chudamani, S., Cibulskis, C., Cibulskis, K., Cope, L., Coupland, S. E., Defreitas, T., Demchok, J. A., Desjardins, L., Dhalla, N., Esmaeli, B., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Gershenwald, J. E., Getz, G., Griewank, K. G., Grimm, E. A., Hayes, D. N., Hegde, A. M., Heiman, D. I., Helsel, C., Hobensack, S., Holt, R. A., Hoyle, A. P., Hu, X., Hutter, C. M., Jager, M. J., Jefferys, S. R., Jones, C. D., Jones, S. J. M., Kandoth, C., Kasaian, K., Kim, J., Kucherlapati, R., Lander, E., Lawrence, M. S., Lazar, A. J., Lee, S., Leraas, K. M., Lin, P., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Mahadeshwar, H. S., Mariani, O., Marra, M. A., Mayo, M., Meier, S., Meng, S., Meyerson, M., Mieczkowski, P. A., Mills, G. B., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Pihl, T., Pilarski, R., Protopopov, A., Radenbaugh, A., Rai, K., Ramirez, N. C., Ren, X., Reynolds, S. M., Roach, J., Roman-Roman, S., Roszik, J., Sadeghi, S., Saksena, G., Sastre, X., Schadendorf, D., Schein, J. E., Schoenfield, L., Schumacher, S. E., Seidman, J., Seth, S., Sethi, G., Sheth, M., Shi, Y., Shields, C., Shmulevich, I., Simons, J. V., Singh, A. D., Sipahimalani, P., Skelly, T., Sofia, H., Soloway, M. G., Song, X., Stern, M. H., Stuart, J., Sun, Q., Sun, H., Tam, A., Tan, D., Tang, J., Tarnuzzer, R., Taylor, B. S., Thiessen, N., Thorsson, V., Tse, K., Veluvolu, U., Verhaak, R. G. W., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Wilkerson, M. D., Williams, M. D., Wise, L., Woodman, S. E., Wong, T., Wu, Y., Yang, L., Yang, L., Zenklusen, J. C., Zhang, J., Zhang, H. & Zmuda, E., Aug 14 2017, In: Cancer Cell. 32, 2, p. 204-220.e15

    Research output: Contribution to journal › Article › peer-review

    Open Access
    560 Scopus citations

  • Integrative clustering reveals a novel split in the luminal A subtype of breast cancer with impact on outcome

    Aure, M. R., Vitelli, V., Jernström, S., Kumar, S., Krohn, M., Due, E. U., Haukaas, T. H., Leivonen, S. K., Vollan, H. K. M., Lüders, T., Rødland, E., Vaske, C. J., Zhao, W., Møller, E. K., Nord, S., Giskeødegård, G. F., Bathen, T. F., Caldas, C., Tramm, T., Alsner, J., & 26 othersOvergaard, J., Geisler, J., Bukholm, I. R. K., Naume, B., Schlichting, E., Sauer, T., Mills, G. B., Kåresen, R., Mælandsmo, G. M., Lingjærde, O. C., Frigessi, A., Kristensen, V. N., Børresen-Dale, A. L., Sahlberg, K. K., Borgen, E., Engebråten, O., Fodstad, Ø., Fritzman, B., Garred, Ø., Geitvik, G. A., Langerød, A., Hofvind, S., Russnes, H. G., Skjerven, H. K., Sørlie, T. & OSBREAC, Mar 29 2017, In: Breast Cancer Research. 19, 1, 44.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    70 Scopus citations

  • Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles

    CONSORTIA, Mar 14 2017, In: Cell Reports. 18, 11, p. 2780-2794 15 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    351 Scopus citations

  • Loss-of-function screens of druggable targetome against cancer stem-like cells

    Song, M., Lee, H., Nam, M. H., Jeong, E., Kim, S., Hong, Y., Kim, N., Yim, H. Y., Yoo, Y. J., Kim, J. S., Kim, J. S., Cho, Y. Y., Mills, G. B., Kim, W. Y. & Yoon, S., Feb 2017, In: FASEB Journal. 31, 2, p. 625-935 311 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations

  • Molecular heterogeneity at the network level: High-dimensional testing, clustering and a TCGA case study

    Städler, N., Dondelinger, F., Hill, S. M., Akbani, R., Lu, Y., Mills, G. B. & Mukherjee, S., Sep 15 2017, In: Bioinformatics. 33, 18, p. 2890-2896 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Multiplatform-based molecular subtypes of non-small-cell lung cancer

    Chen, F., Zhang, Y., Parra, E., Rodriguez, J., Behrens, C., Akbani, R., Lu, Y., Kurie, J. M., Gibbons, D. L., Mills, G. B., Wistuba, I. I. & Creighton, C. J., Mar 1 2017, In: Oncogene. 36, 10, p. 1384-1393 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    94 Scopus citations

  • Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer

    Kang, M. H., Jeong, K. J., Kim, W. Y., Lee, H. J., Gong, G., Suh, N., Gyrffy, B., Kim, S., Jeong, S. Y., Mills, G. B. & Park, Y. Y., Mar 23 2017, In: Oncogene. 36, 12, p. 1745-1752 8 p.

    Research output: Contribution to journal › Article › peer-review

    53 Scopus citations

  • Next-Generation Sequencing and Result Interpretation in Clinical Oncology: Challenges of Personalized Cancer Therapy

    Khotskaya, Y. B., Mills, G. B. & Mills Shaw, K. R., Jan 14 2017, In: Annual review of medicine. 68, p. 113-125 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    34 Scopus citations

  • Niche-localized tumor cells are protected from HER2-targeted therapy via upregulation of an anti-apoptotic program in vivo

    Zoeller, J. J., Bronson, R. T., Selfors, L. M., Mills, G. B. & Brugge, J. S., Dec 1 2017, In: npj Breast Cancer. 3, 1, 18.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    16 Scopus citations

  • Oncogenic RAS Regulates Long Noncoding RNA Orilnc1 in Human Cancer

    Zhang, D., Zhang, G., Hu, X., Wu, L., Feng, Y., He, S., Zhang, Y., Hu, Z., Yang, L., Tian, T., Xu, W., Wei, Z., Lu, Y., Flaherty, K. T., Zhong, X., Mills, G. B., Gimotty, P. A., Xu, X., Herlyn, M. & Zhang, L., Jul 15 2017, In: Cancer Research. 77, 14, p. 3745-3757 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Scopus citations

  • PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

    Lu, H., Liu, S., Zhang, G., Wu, B., Zhu, Y., Frederick, D. T., Hu, Y., Zhong, W., Randell, S., Sadek, N., Zhang, W., Chen, G., Cheng, C., Zeng, J., Wu, L. W., Zhang, J., Liu, X., Xu, W., Krepler, C., Sproesser, K., & 21 othersXiao, M., Miao, B., Liu, J., Song, C. D., Liu, J. Y., Karakousis, G. C., Schuchter, L. M., Lu, Y., Mills, G., Cong, Y., Chernoff, J., Guo, J., Boland, G. M., Sullivan, R. J., Wei, Z., Field, J., Amaravadi, R. K., Flaherty, K. T., Herlyn, M., Xu, X. & Guo, W., Oct 5 2017, In: Nature. 550, 7674, p. 133-136 4 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    128 Scopus citations

  • Personalized cancer therapy: A publicly available precision oncology resource

    Kurnit, K. C., Bailey, A. M., Zeng, J., Johnson, A. M., Shufean, M. A., Brusco, L., Litzenburger, B. C., Sanchez, N. S., Khotskaya, Y. B., Holla, V., Simpson, A., Mills, G. B., Mendelsohn, J., Bernstam, E., Shaw, K. & Meric-Bernstam, F., Nov 1 2017, In: Cancer Research. 77, 21, p. e123-e126

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • Phase I dose escalation study of the PI3kinase pathway inhibitor BKM120 and the oral poly (ADP ribose) polymerase (PARP) inhibitor olaparib for the treatment of high-grade serous ovarian and breast cancer

    Matulonis, U. A., Wulf, G. M., Barry, W. T., Birrer, M., Westin, S. N., Farooq, S., Bell-McGuinn, K. M., Obermayer, E., Whalen, C., Spagnoletti, T., Luo, W., Liu, H., Hok, R. C., Aghajanian, C., Solit, D. B., Mills, G. B., Taylor, B. S., Won, H., Berger, M. F., Palakurthi, S., & 3 othersLiu, J., Cantley, L. C. & Winer, E., Mar 2017, In: Annals of Oncology. 28, 3, p. 512-518 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    163 Scopus citations

  • PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer

    Mjos, S., Werner, H. M. J., Birkeland, E., Holst, F., Berg, A., Halle, M. K., Tangen, I. L., Kusonmano, K., Mauland, K. K., Oyan, A. M., Kalland, K. H., Lewis, A. E., Mills, G. B., Krakstad, C., Trovik, J., Salvesen, H. B. & Hoivik, E. A., Dec 1 2017, In: Scientific Reports. 7, 1, 10240.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival

    Clarke, C. N., Lee, M. S., Wei, W., Manyam, G., Jiang, Z. Q., Lu, Y., Morris, J., Broom, B., Menter, D., Vilar-Sanchez, E., Raghav, K., Eng, C., Chang, G. J., Simon, I., Bernards, R., Overman, M., Mills, G. B., Maru, D. & Kopetz, S., Dec 1 2017, In: Annals of surgical oncology. 24, 13, p. 4051-4058 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations