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Gordon Mills

Director of Precision Oncology

Calculated based on number of publications stored in Pure and citations from Scopus
1976 …2024

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  • 2016

    Proteomic characterization of head and neck cancer patient-derived xenografts

    Li, H., Wheeler, S., Park, Y., Ju, Z., Thomas, S. M., Fichera, M., Egloff, A. M., Lui, V. W., Duvvuri, U., Bauman, J. E., Mills, G. B. & Grandis, J. R., Mar 2016, In: Molecular Cancer Research. 14, 3, p. 278-286 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    41 Scopus citations

  • Rab11-FIP1C is a critical negative regulator in ErbB2-mediated mammary tumor progression

    Boulay, P. L., Mitchell, L., Turpin, J., Huot-Marchand, J. É., Lavoie, C., Sanguin-Gendreau, V., Jones, L., Mitra, S., Livingstone, J. M., Campbell, S., Hallett, M., Mills, G. B., Park, M., Chodosh, L., Strathdee, D., Norman, J. C. & Muller, W. J., May 1 2016, In: Cancer Research. 76, 9, p. 2662-2674 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Scopus citations

  • Rab25 acts as an oncogene in luminal B breast cancer and is causally associated with Snail driven EMT

    Mitra, S., Federico, L., Zhao, W., Dennison, J., Sarkar, T. R., Zhang, F., Takiar, V., Cheng, K. W., Mani, S., Lee, J. S. & Mills, G. B., 2016, In: Oncotarget. 7, 26, p. 40252-40265 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors

    Zhang, G., Frederick, D. T., Wu, L., Wei, Z., Krepler, C., Srinivasan, S., Chae, Y. C., Xu, X., Choi, H., Dimwamwa, E., Ope, O., Shannan, B., Basu, D., Zhang, D., Guha, M., Xiao, M., Randell, S., Sproesser, K., Xu, W., Liu, J., & 22 othersKarakousis, G. C., Schuchter, L. M., Gangadhar, T. C., Amaravadi, R. K., Gu, M., Xu, C., Ghosh, A., Xu, W., Tian, T., Zhang, J., Zha, S., Liu, Q., Brafford, P., Weeraratna, A., Davies, M. A., Wargo, J. A., Avadhani, N. G., Lu, Y., Mills, G. B., Altieri, D. C., Flaherty, K. T. & Herlyn, M., May 2 2016, In: Journal of Clinical Investigation. 126, 5, p. 1834-1856 23 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    200 Scopus citations

  • The degree of intratumor mutational heterogeneity varies by primary tumor sub-site

    Ledgerwood, L. G., Kumar, D., Eterovic, A. K., Wick, J., Chen, K., Zhao, H., Tazi, L., Manna, P., Kerley, S., Joshi, R., Wang, L., Chiosea, S. I., Garnett, J. D., Tsue, T. T., Chien, J., Mills, G. B., Grandis, J. R. & Thomas, S. M., May 10 2016, In: Oncotarget. 7, 19, p. 27185-27198 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Scopus citations

  • The ErbB2ΔEx16 splice variant is a major oncogenic driver in breast cancer that promotes a pro-metastatic tumor microenvironment

    Turpin, J., Ling, C., Crosby, E. J., Hartman, Z. C., Simond, A. M., Chodosh, L. A., Rennhack, J. P., Andrechek, E. R., Ozcelik, J., Hallett, M., Mills, G. B., Cardiff, R. D., Gray, J. W., Griffith, O. L. & Muller, W. J., Nov 24 2016, In: Oncogene. 35, 47, p. 6053-6064 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    51 Scopus citations

  • Transgenic expression of the mitochondrial chaperone TNFR-associated protein 1 (TRAP1) accelerates prostate cancer development

    Lisanti, S., Garlick, D. S., Bryant, K. G., Tavecchio, M., Mills, G. B., Lu, Y., Kossenkov, A. V., Showe, L. C., Languino, L. R. & Altieri, D. C., Nov 25 2016, In: Journal of Biological Chemistry. 291, 48, p. 25247-25254 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials

    Overman, M. J., Morris, V., Kee, B., Fogelman, D., Xiao, L., Eng, C., Dasari, A., Shroff, R., Mazard, T., Shaw, K., Vilar, E., Raghav, K., Shureiqi, I., Liang, L., Mills, G. B., Wolff, R. A., Hamilton, S., Meric-Bernstam, F., Abbruzzese, J., Morris, J., & 2 othersMaru, D. & Kopetz, S., Jun 18 2016, In: Annals of Oncology. 27, 6, p. 1068-1074 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    24 Scopus citations

  • Verteporfin inhibits YAP function through up-regulating 14-3-3σ sequestering YAP in the cytoplasm

    Wang, C., Zhu, X., Feng, W., Yu, Y., Jeong, K., Guo, W., Lu, Y. & Mills, G. B., 2016, In: American Journal of Cancer Research. 6, 1, p. 27-37 11 p.

    Research output: Contribution to journal › Article › peer-review

    207 Scopus citations

  • Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma

    Park, Y. Y., Sohn, B. H., Johnson, R. L., Kang, M. H., Kim, S. B., Shim, J. J., Mangala, L. S., Kim, J. H., Yoo, J. E., Rodriguez-Aguayo, C., Pradeep, S., Hwang, J. E., Jang, H. J., Lee, H. S., Rupaimoole, R., Lopez-Berestein, G., Jeong, W., Park, I. S., Park, Y. N., Sood, A. K., & 2 othersMills, G. B. & Lee, J. S., Jan 1 2016, In: Hepatology. 63, 1, p. 159-172 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    108 Scopus citations
  • 2015

    Ability to generate patient-derived Breast cancer xenografts is enhanced in chemoresistant disease and predicts poor patient outcomes

    McAuliffe, P. F., Evans, K. W., Akcakanat, A., Chen, K., Zheng, X., Zhao, H., Eterovic, A. K., Sangai, T., Holder, A. M., Sharma, C., Chen, H., Do, K. A., Tarco, E., Gagea, M., Naff, K. A., Sahin, A., Multani, A. S., Black, D. M., Mittendorf, E. A., Bedrosian, I., & 3 othersMills, G. B., Gonzalez-Angulo, A. M. & Meric-Bernstam, F., Sep 1 2015, In: PloS one. 10, 9, e0136851.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • An integrated molecular analysis of lung adenocarcinomas identifies potential therapeutic targets among TTF1-negative tumors, including DNA Repair Proteins and Nrf2

    Cardnell, R. J. G., Behrens, C., Diao, L., Fan, Y. H., Tang, X., Tong, P., Minna, J. D., Mills, G. B., Heymach, J. V., Wistuba, I. I., Wang, J. & Byers, L. A., Aug 1 2015, In: Clinical Cancer Research. 21, 15, p. 3480-3491 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • A putative biomarker signature for clinically effective AKT inhibition: Correlation of in vitro, in vivo and clinical data identifies the importance of modulation of the mTORC1 pathway

    Cheraghchi-Bashi, A., Parker, C. A., Curry, E., Salazar, J. F., Gungor, H., Saleem, A., Cunnea, P., Rama, N., Salinas, C., Mills, G. B., Morris, S. R., Kumar, R., Gabra, H. & Stronach, E. A., 2015, In: Oncotarget. 6, 39, p. 41736-41749 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    23 Scopus citations

  • ARID1A Deficiency Impairs the DNA Damage Checkpoint and Sensitizes Cells to PARP Inhibitors

    Shen, J., Peng, Y., Wei, L., Zhang, W., Yang, L., Lan, L., Kapoor, P., Ju, Z., Mo, Q., Shih, I. M., Uray, I. P., Wu, X., Brown, P. H., Shen, X., Mills, G. B. & Peng, G., Jul 2015, In: Cancer discovery. 5, 7, p. 752-767 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    343 Scopus citations

  • Association of somatic mutations of ADAMTS genes with chemotherapy sensitivity and survival in high-grade serous ovarian carcinoma

    Liu, Y., Yasukawa, M., Chen, K., Hu, L., Broaddus, R. R., Ding, L., Mardis, E. R., Spellman, P., Levine, D. A., Mills, G. B., Shmulevich, I., Sood, A. K. & Zhang, W., Jul 1 2015, In: JAMA Oncology. 1, 4, p. 486-494 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations

  • Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis

    Liu, X. D., Yao, J., Tripathi, D. N., Ding, Z., Xu, Y., Sun, M., Zhang, J., Bai, S., German, P., Hoang, A., Zhou, L., Jonasch, D., Zhang, X., Conti, C. J., Efstathiou, E., Tannir, N. M., Eissa, N. T., Mills, G. B., Walker, C. L. & Jonasch, E., May 7 2015, In: Oncogene. 34, 19, p. 2450-2460 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    61 Scopus citations

  • Beyond BRAFV600: Clinical mutation panel testing by next-generation sequencing in advanced melanoma

    Siroy, A. E., Boland, G. M., Milton, D. R., Roszik, J., Frankian, S., Malke, J., Haydu, L., Prieto, V. G., Tetzlaff, M., Ivan, D., Wang, W. L., Torres-Cabala, C., Curry, J., Roy-Chowdhuri, S., Broaddus, R., Rashid, A., Stewart, J., Gershenwald, J. E., Amaria, R. N., Patel, S. P., & 17 othersPapadopoulos, N. E., Bedikian, A., Hwu, W. J., Hwu, P., Diab, A., Woodman, S. E., Aldape, K. D., Luthra, R., Patel, K. P., Shaw, K. R., Mills, G. B., Mendelsohn, J., Meric-Bernstam, F., Kim, K. B., Routbort, M. J., Lazar, A. J. & Davies, M. A., Feb 13 2015, In: Journal of Investigative Dermatology. 135, 2, p. 508-515 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    125 Scopus citations

  • Characterization of the role rab25 in energy metabolism and cancer using extracellular flux analysis and material balance

    Mitra, S., Molina, J., Mills, G. B. & Ennison, J. B. D., 2015, In: Methods in Molecular Biology. 1298, p. 195-205 11 p.

    Research output: Contribution to journal › Article › peer-review

    2 Scopus citations

  • Characterization of twenty-five ovarian tumour cell lines that phenocopy primary tumours

    Ince, T. A., Sousa, A. D., Jones, M. A., Harrell, J. C., Agoston, E. S., Krohn, M., Selfors, L. M., Liu, W., Chen, K., Yong, M., Buchwald, P., Wang, B., Hale, K. S., Cohick, E., Sergent, P., Witt, A., Kozhekbaeva, Z., Gao, S., Agoston, A. T., Merritt, M. A., & 5 othersFoster, R., Rueda, B. R., Crum, C. P., Brugge, J. S. & Mills, G. B., Jun 17 2015, In: Nature communications. 6, 7419.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    136 Scopus citations

  • Clinical actionability enhanced through deep targeted sequencing of solid tumors

    Chen, K., Meric-Bernstam, F., Zhao, H., Zhang, Q., Ezzeddine, N., Tang, L. Y., Qi, Y., Mao, Y., Chen, T., Chong, Z., Zhou, W., Zheng, X., Johnson, A., Aldape, K. D., Routbort, M. J., Luthra, R., Kopetz, S., Davies, M. A., De Groot, J., Moulder, S., & 6 othersVinod, R., Farhangfar, C. J., Shaw, K. M., Mendelsohn, J., Mills, G. B. & Eterovic, A. K., Mar 1 2015, In: Clinical chemistry. 61, 3, p. 544-553 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    84 Scopus citations

  • Clinical next generation sequencing to identify actionable aberrations in a phase I program

    Boland, G. M., Piha-Paul, S. A., Subbiah, V., Routbort, M., Herbrich, S. M., Baggerly, K., Patel, K. P., Brusco, L., Horombe, C., Naing, A., Fu, S., Hong, D. S., Janku, F., Johnson, A., Broaddus, R., Luthra, R., Shaw, K., Mendelsohn, J., Mills, G. B. & Meric-Bernstam, F., 2015, In: Oncotarget. 6, 24, p. 20099-20110 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    40 Scopus citations

  • Co-clinical assessment identifies patterns of BRAF inhibitor resistance in melanoma

    Kwong, L. N., Boland, G. M., Frederick, D. T., Helms, T. L., Akid, A. T., Miller, J. P., Jiang, S., Cooper, Z. A., Song, X., Seth, S., Kamara, J., Protopopov, A., Mills, G. B., Flaherty, K. T., Wargo, J. A. & Chin, L., Apr 1 2015, In: Journal of Clinical Investigation. 125, 4, p. 1459-1470 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    93 Scopus citations

  • Comparison of gene expression patterns across 12 tumor types identifies a cancer supercluster characterized by TP53 mutations and cell cycle defects

    Martínez, E., Yoshihara, K., Kim, H., Mills, G. M., Treviño, V. & Verhaak, R. G. W., May 21 2015, In: Oncogene. 34, 21, p. 2732-2740 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    41 Scopus citations

  • Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas

    Brat, D. J., Verhaak, R. G. W., Aldape, K. D., Yung, W. K. A., Salama, S. R., Cooper, L. A. D., Rheinbay, E., Miller, C. R., Vitucci, M., Morozova, O., Robertson, A. G., Noushmehr, H., Laird, P. W., Cherniack, A. D., Akbani, R., Huse, J. T., Ciriello, G., Poisson, L. M., Barnholtz-Sloan, J. S., Berger, M. S., & 287 othersBrennan, C., Colen, R. R., Colman, H., Flanders, A. E., Giannini, C., Grifford, M., Iavarone, A., Jain, R., Joseph, I., Kim, J., Kasaian, K., Mikkelsen, T., Murray, B. A., O'Neill, B. P., Pachter, L., Parsons, D. W., Sougnez, C., Sulman, E. P., Vandenberg, S. R., Van Meir, E. G., Von Deimling, A., Zhang, H., Crain, D., Lau, K., Mallery, D., Morris, S., Paulauskis, J., Penny, R., Shelton, T., Sherman, M., Yena, P., Black, A., Bowen, J., Dicostanzo, K., Gastier-Foster, J., Leraas, K. M., Lichtenberg, T. M., Pierson, C. R., Ramirez, N. C., Taylor, C., Weaver, S., Wise, L., Zmuda, E., Davidsen, T., Demchok, J. A., Eley, G., Ferguson, M. L., Hutter, C. M., Shaw, K. R. M., Ozenberger, B. A., Sheth, M., Sofia, H. J., Tarnuzzer, R., Wang, Z., Yang, L., Zenklusen, J. C., Ayala, B., Baboud, J., Chudamani, S., Jensen, M. A., Liu, J., Pihl, T., Raman, R., Wan, Y., Wu, Y., Ally, A., Auman, J. T., Balasundaram, M., Balu, S., Baylin, S. B., Beroukhim, R., Bootwalla, M. S., Bowlby, R., Bristow, C. A., Brooks, D., Butterfield, Y., Carlsen, R., Carter, S., Chin, L., Chu, A., Chuah, E., Cibulskis, K., Clarke, A., Coetzee, S. G., Dhalla, N., Fennell, T., Fisher, S., Gabriel, S., Getz, G., Gibbs, R., Guin, R., Hadjipanayis, A., Hayes, D. N., Hinoue, T., Hoadley, K., Holt, R. A., Hoyle, A. P., Jefferys, S. R., Jones, S., Jones, C. D., Kucherlapati, R., Lai, P. H., Lander, E., Lee, S., Lichtenstein, L., Ma, Y., Maglinte, D. T., Mahadeshwar, H. S., Marra, M. A., Mayo, M., Meng, S., Meyerson, M. L., Mieczkowski, P. A., Moore, R. A., Mose, L. E., Mungall, A. J., Pantazi, A., Parfenov, M., Park, P. J., Parker, J. S., Perou, C. M., Protopopov, A., Ren, X., Roach, J., Sabedot, T. S., Schein, J., Schumacher, S. E., Seidman, J. G., Seth, S., Shen, H., Simons, J. V., Sipahimalani, P., Soloway, M. G., Song, X., Sun, H., Tabak, B., Tam, A., Tan, D., Tang, J., Thiessen, N., Triche, T., Van Den Berg, D. J., Veluvolu, U., Waring, S., Weisenberger, D. J., Wilkerson, M. D., Wong, T., Wu, J., Xi, L., Xu, A. W., Yang, L., Zack, T. I., Zhang, J., Aksoy, B. A., Arachchi, H., Benz, C., Bernard, B., Carlin, D., Cho, J., DiCara, D., Frazer, S., Fuller, G. N., Gao, J. J., Gehlenborg, N., Haussler, D., Heiman, D. I., Iype, L., Jacobsen, A., Ju, Z., Katzman, S., Kim, H., Knijnenburg, T., Kreisberg, R. B., Lawrence, M. S., Lee, W., Leinonen, K., Lin, P., Ling, S., Liu, W., Liu, Y., Liu, Y., Lu, Y., Mills, G., Ng, S., Noble, M. S., Paull, E., Rao, A., Reynolds, S., Saksena, G., Sanborn, Z., Sander, C., Schultz, N., Senbabaoglu, Y., Shen, R., Shmulevich, I., Sinha, R., Stuart, J., Sumer, S. O., Sun, Y., Tasman, N., Taylor, B. S., Voet, D., Weinhold, N., Weinstein, J. N., Yang, D., Yoshihara, K., Zheng, S., Zhang, W., Zou, L., Abel, T., Sadeghi, S., Cohen, M. L., Eschbacher, J., Hattab, E. M., Raghunathan, A., Schniederjan, M. J., Aziz, D., Barnett, G., Barrett, W., Bigner, D. D., Boice, L., Brewer, C., Calatozzolo, C., Campos, B., Carlotti, C. G., Chan, T. A., Cuppini, L., Curley, E., Cuzzubbo, S., Devine, K., DiMeco, F., Duell, R., Elder, J. B., Fehrenbach, A., Finocchiaro, G., Friedman, W., Fulop, J., Gardner, J., Hermes, B., Herold-Mende, C., Jungk, C., Kendler, A., Lehman, N. L., Lipp, E., Liu, O., Mandt, R., McGraw, M., Mclendon, R., McPherson, C., Neder, L., Nguyen, P., Noss, A., Nunziata, R., Ostrom, Q. T., Palmer, C., Perin, A., Pollo, B., Potapov, A., Potapova, O., Rathmell, W. K., Rotin, D., Scarpace, L., Schilero, C., Senecal, K., Shimmel, K., Shurkhay, V., Sifri, S., Singh, R., Sloan, A. E., Smolenski, K., Staugaitis, S. M., Steele, R., Thorne, L., Tirapelli, D. P. C., Unterberg, A., Vallurupalli, M., Wang, Y., Warnick, R., Williams, F., Wolinsky, Y., Bell, S., Rosenberg, M., Stewart, C., Huang, F., Grimsby, J. L., Radenbaugh, A. J. & Zhang, J., Jun 25 2015, In: New England Journal of Medicine. 372, 26, p. 2481-2498 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2270 Scopus citations

  • Comprehensive genomic analysis identifies novel subtypes and targets of triple-negative breast cancer

    Burstein, M. D., Tsimelzon, A., Poage, G. M., Covington, K. R., Contreras, A., Fuqua, S. A. W., Savage, M. I., Osborne, C. K., Hilsenbeck, S. G., Chang, J. C., Mills, G. B., Lau, C. C. & Brown, P. H., Apr 1 2015, In: Clinical Cancer Research. 21, 7, p. 1688-1698 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    897 Scopus citations

  • Comprehensive genomic characterization of head and neck squamous cell carcinomas

    The Cancer Genome Atlas Network, Jan 29 2015, In: Nature. 517, 7536, p. 576-582 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2873 Scopus citations

  • Comprehensive Genomic Characterization of Long Non-coding RNAs across Human Cancers

    Yan, X., Hu, Z., Feng, Y., Hu, X., Yuan, J., Zhao, S. D., Zhang, Y., Yang, L., Shan, W., He, Q., Fan, L., Kandalaft, L. E., Tanyi, J. L., Li, C., Yuan, C. X., Zhang, D., Yuan, H., Hua, K., Lu, Y., Katsaros, D., & 10 othersHuang, Q., Montone, K., Fan, Y., Coukos, G., Boyd, J., Sood, A. K., Rebbeck, T., Mills, G. B., Dang, C. V. & Zhang, L., Oct 12 2015, In: Cancer Cell. 28, 4, p. 529-540 12 p., 2143.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    545 Scopus citations

  • Comprehensive Molecular Portraits of Invasive Lobular Breast Cancer

    Ciriello, G., Gatza, M. L., Beck, A. H., Wilkerson, M. D., Rhie, S. K., Pastore, A., Zhang, H., McLellan, M., Yau, C., Kandoth, C., Bowlby, R., Shen, H., Hayat, S., Fieldhouse, R., Lester, S. C., Tse, G. M. K., Factor, R. E., Collins, L. C., Allison, K. H., Chen, Y. Y., & 119 othersJensen, K., Johnson, N. B., Oesterreich, S., Mills, G. B., Cherniack, A. D., Robertson, G., Benz, C., Sander, C., Laird, P. W., Hoadley, K. A., King, T. A., Akbani, R., Auman, J. T., Balasundaram, M., Balu, S., Barr, T., Benz, S., Berrios, M., Beroukhim, R., Bodenheimer, T., Boice, L., Bootwalla, M. S., Bowen, J., Brooks, D., Chin, L., Cho, J., Chudamani, S., Davidsen, T., Demchok, J. A., Dennison, J. B., Ding, L., Felau, I., Ferguson, M. L., Frazer, S., Gabriel, S. B., Gao, J. J., Gastier-Foster, J. M., Gehlenborg, N., Gerken, M., Getz, G., Gibson, W. J., Hayes, D. N., Heiman, D. I., Holbrook, A., Holt, R. A., Hoyle, A. P., Hu, H., Huang, M., Hutter, C. M., Hwang, E. S., Jefferys, S. R., Jones, S. J. M., Ju, Z., Kim, J., Lai, P. H., Lawrence, M. S., Leraas, K. M., Lichtenberg, T. M., Lin, P., Ling, S., Liu, J., Liu, W., Lolla, L., Lu, Y., Ma, Y., Maglinte, D. T., Mardis, E., Marks, J., Marra, M. A., McAllister, C., Meng, S., Meyerson, M., Moore, R. A., Mose, L. E., Mungall, A. J., Murray, B. A., Naresh, R., Noble, M. S., Olopade, O., Parker, J. S., Pihl, T., Saksena, G., Schumacher, S. E., Shaw, K. R. M., Ramirez, N. C., Rathmell, W. K., Roach, J., Robertson, A. G., Schein, J. E., Schultz, N., Sheth, M., Shi, Y., Shih, J., Shelley, C. S., Shriver, C., Simons, J. V., Sofia, H. J., Soloway, M. G., Sougnez, C., Sun, C., Tarnuzzer, R., Tiezzi, D. G., Van Den Berg, D. J., Voet, D., Wan, Y., Wang, Z., Weinstein, J. N., Weisenberger, D. J., Wilson, R., Wise, L., Wiznerowicz, M., Wu, J., Wu, Y., Yang, L., Zack, T. I., Zenklusen, J. C., Zhang, J., Zmuda, E. & Perou, C. M., Oct 8 2015, In: Cell. 163, 2, p. 506-519 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1290 Scopus citations

  • Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

    Skoulidis, F., Byers, L. A., Diao, L., Papadimitrakopoulou, V. A., Tong, P., Izzo, J., Behrens, C., Kadara, H., Parra, E. R., Canales, J. R., Zhang, J., Giri, U., Gudikote, J., Cortez, M. A., Yang, C., Fan, Y., Peyton, M., Girard, L., Coombes, K. R., Toniatti, C., & 17 othersHeffernan, T. P., Choi, M., Frampton, G. M., Miller, V., Weinstein, J. N., Herbst, R. S., Wong, K. K., Zhang, J., Sharma, P., Mills, G. B., Hong, W. K., Minna, J. D., Allison, J. P., Futrea, A., Wang, J., Wistuba, I. I. & Heymach, J. V., Aug 1 2015, In: Cancer discovery. 5, 8, p. 861-878 18 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    654 Scopus citations

  • Cupid: Simultaneous reconstruction of micrornatarget and cerna networks

    Chiu, H. S., Llobet-Navas, D., Yang, X., Chung, W. J., Ambesi-Impiombato, A., Iyer, A., Kim, H. R., Seviour, E. G., Luo, Z., Sehgal, V., Moss, T., Lu, Y., Ram, P., Silva, J., Mills, G. B., Califano, A. & Sumazin, P., Feb 1 2015, In: Genome Research. 25, 2, p. 257-267 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    82 Scopus citations

  • Cytoplasmic p27 promotes epithelial-mesenchymal transition and tumor metastasis via STAT3-mediated Twist1 upregulation

    Zhao, D., Besser, A. H., Wander, S. A., Sun, J., Zhou, W., Wang, B., Ince, T., Durante, M. A., Guo, W., Mills, G., Theodorescu, D. & Slingerland, J., Oct 1 2015, In: Oncogene. 34, 43, p. 5447-5459 13 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    98 Scopus citations

  • Death-associated protein kinase 1 promotes growth of p53-mutant cancers

    Zhao, J., Zhao, D., Poage, G. M., Mazumdar, A., Zhang, Y., Hill, J. L., Hartman, Z. C., Savage, M. I., Mills, G. B. & Brown, P. H., Jul 1 2015, In: Journal of Clinical Investigation. 125, 7, p. 2707-2720 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    49 Scopus citations

  • Decoupling of the PI3K pathway via mutation necessitates combinatorial treatment in HER2+ breast cancer

    Korkola, J. E., Collisson, E. A., Heiser, L., Oates, C., Bayani, N., Itani, S., Esch, A., Thompson, W., Griffith, O. L., Wang, N., Kuo, W. L., Cooper, B., Billig, J., Ziyad, S., Hung, J. L., Feiler, H., Lu, Y., Mills, G. B., Spellman, P. T., Tomlin, C., & 3 othersMukherjee, S., Gray, J. W. & Jakkula, L., Jul 16 2015, In: PloS one. 10, 7, e0133219.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    17 Scopus citations

  • Development of a robust classifier for quality control of reverse-phase protein arrays

    Ju, Z., Liu, W., Roebuck, P. L., Siwak, D. R., Zhang, N., Lu, Y., Davies, M. A., Akbani, R., Weinstein, J. N., Mills, G. B. & Coombes, K. R., Mar 15 2015, In: Bioinformatics. 31, 6, p. 912-918 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Scopus citations

  • Elafin drives poor outcome in high-grade serous ovarian cancers and basal-like breast tumors

    Labidi-Galy, S. I., Clauss, A., Ng, V., Duraisamy, S., Elias, K. M., Piao, H. Y., Bilal, E., Davidowitz, R. A., Lu, Y., Badalian-Very, G., Györffy, B., Kang, U. B., Ficarro, S., Ganesan, S., Mills, G. B., Marto, J. A. & Drapkin, R., Jan 15 2015, In: Oncogene. 34, 3, p. 299-309 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    43 Scopus citations

  • Feasibility of large-scale genomic testing to facilitate enrollment onto genomically matched clinical trials

    Meric-Bernstam, F., Brusco, L., Shaw, K., Horombe, C., Kopetz, S., Davies, M. A., Routbort, M., Piha-Paul, S. A., Janku, F., Ueno, N., Hong, D., De Groot, J., Ravi, V., Li, Y., Luthra, R., Patel, K., Broaddus, R., Mendelsohn, J. & Mills, G. B., Sep 1 2015, In: Journal of Clinical Oncology. 33, 25, p. 2753-2762 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    331 Scopus citations

  • Functional consequence of the MET-T1010I polymorphism in breast cancer

    Liu, S., Meric-Bernstam, F., Parinyanitikul, N., Wang, B., Eterovic, A. K., Zheng, X., Gagea, M., Chavez-MacGregor, M., Ueno, N. T., Lei, X., Zhou, W., Nair, L., Tripathy, D., Brown, P. H., Hortobagyi, G. N., Chen, K., Mendelsohn, J., Mills, G. B. & Gonzalez-Angulo, A. M., 2015, In: Oncotarget. 6, 5, p. 2604-2614 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    33 Scopus citations

  • Genetic events that limit the efficacy of MEK and RTK inhibitor therapies in a mouse model of KRAS-driven pancreatic cancer

    Pettazzoni, P., Viale, A., Shah, P., Carugo, A., Ying, H., Wang, H., Genovese, G., Seth, S., Minelli, R., Green, T., Huang-Hobbs, E., Corti, D., Sanchez, N., Nezi, L., Marchesini, M., Kapoor, A., Yao, W., Di Francesco, M. E., Petrocchi, A., Deem, A. K., & 9 othersScott, K., Colla, S., Mills, G. B., Fleming, J. B., Heffernan, T. P., Jones, P., Toniatti, C., Depinho, R. A. & Draetta, G. F., Mar 15 2015, In: Cancer Research. 75, 6, p. 1091-1101 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    64 Scopus citations

  • Genome-wide perturbations by miRNAs map onto functional cellular pathways, identifying regulators of chromatin modifiers

    Moss, T. J., Luo, Z., Seviour, E. G., Sehgal, V., Lu, Y., Hill, S. M., Rupaimoole, R., Lee, J. S., Rodriguez-Aguayo, C., Lopez-Berestein, G., Sood, A. K., Azencott, R., Gray, J. W., Mukherjee, S., Mills, G. B. & Ram, P. T., Sep 28 2015, In: npj Systems Biology and Applications. 1, 15001.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    3 Scopus citations

  • Genomic Classification of Cutaneous Melanoma

    The Cancer Genome Atlas Network, Jun 20 2015, In: Cell. 161, 7, p. 1681-1696 16 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2234 Scopus citations

  • Genomic correlate of exceptional erlotinib response in head and neck squamous cell carcinoma

    Van Allen, E. M., Lui, V. W. Y., Egloff, A. M., Goetz, E. M., Li, H., Johnson, J. T., Duvvuri, U., Bauman, J. E., Stransky, N., Zeng, Y., Gilbert, B. R., Pendleton, K. P., Wang, L., Chiosea, S., Sougnez, C., Wagle, N., Zhang, F., Du, Y., Close, D., Johnston, P. A., & 7 othersMcKenna, A., Carter, S. L., Golub, T. R., Getz, G., Mills, G. B., Garraway, L. A. & Grandis, J. R., May 1 2015, In: JAMA Oncology. 1, 2, p. 238-244 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • Homeostasis of redox status derived from glucose metabolic pathway could be the key to understanding the Warburg effect

    Zhang, S., Yang, C., Yang, Z., Zhang, D., Ma, X., Mills, G. & Liu, Z., 2015, In: American Journal of Cancer Research. 5, 4, p. 1265-1280 16 p.

    Research output: Contribution to journal › Article › peer-review

    29 Scopus citations

  • HTERT mediates norepinephrine-induced Slug expression and ovarian cancer aggressiveness

    Choi, M. J., Cho, K. H., Lee, S., Bae, Y. J., Jeong, K. J., Rha, S. Y., Choi, E. J., Park, J. H., Kim, J. M., Lee, J. S., Mills, G. B. & Lee, H. Y., Jun 27 2015, In: Oncogene. 34, 26, p. 3402-3412 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    58 Scopus citations

  • Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutations

    Dogruluk, T., Tsang, Y. H., Espitia, M., Chen, F., Chen, T., Chong, Z., Appadurai, V., Dogruluk, A., Eterovic, A. K., Bonnen, P. E., Creighton, C. J., Chen, K., Mills, G. B. & Scott, K. L., Dec 15 2015, In: Cancer Research. 75, 24, p. 5341-5354 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    117 Scopus citations

  • Integrated analysis reveals microRNA networks coordinately expressed with key proteins in breast cancer

    Oslo Breast Cancer Research Consortium (OSBREAC), Feb 2 2015, In: Genome Medicine. 7, 1, 21.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    32 Scopus citations

  • Large-scale drug screens support precision medicine

    Gray, J. W. & Mills, G. B., Nov 2015, In: Cancer discovery. 5, 11, p. 1130-1132 3 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Long Noncoding RNA Ceruloplasmin Promotes Cancer Growth by Altering Glycolysis

    Rupaimoole, R., Lee, J., Haemmerle, M., Ling, H., Previs, R. A., Pradeep, S., Wu, S. Y., Ivan, C., Ferracin, M., Dennison, J. B., Millward, N. M. Z., Nagaraja, A. S., Gharpure, K. M., McGuire, M., Sam, N., Armaiz-Pena, G. N., Sadaoui, N. C., Rodriguez-Aguayo, C., Calin, G. A., Drapkin, R. I., & 6 othersKovacs, J., Mills, G. B., Zhang, W., Lopez-Berestein, G., Bhattacharya, P. K. & Sood, A. K., Dec 22 2015, In: Cell Reports. 13, 11, p. 2395-2402 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    96 Scopus citations

  • Metabolic stress induces a Wnt-dependent cancer stem cell-like state transition

    Lee, E., Yang, J., Ku, M., Kim, N. H., Park, Y., Park, C. B., Suh, J. S., Park, E. S., Yook, J. I., Mills, G. B., Huh, Y. M. & Cheong, J. H., Jul 2 2015, In: Cell Death and Disease. 6, e1805.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    35 Scopus citations

  • Modulation of breast cancer risk biomarkers by high-dose omega-3 fatty acids: Phase II pilot study in postmenopausal women

    Fabian, C. J., Kimler, B. F., Phillips, T. A., Nydegger, J. L., Kreutzjans, A. L., Carlson, S. E., Hidaka, B. H., Metheny, T., Zalles, C. M., Mills, G. B., Powers, K. R., Sullivan, D. K., Petroff, B. K., Hensing, W. L., Fridley, B. L. & Hursting, S. D., Oct 1 2015, In: Cancer Prevention Research. 8, 10, p. 922-931 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Modulation of breast cancer risk biomarkers by high-dose omega-3 fatty acids: Phase II pilot study in premenopausal women

    Fabian, C. J., Kimler, B. F., Phillips, T. A., Box, J. A., Kreutzjans, A. L., Carlson, S. E., Hidaka, B. H., Metheny, T., Zalles, C. M., Mills, G. B., Powers, K. R., Sullivan, D. K., Petroff, B. K., Hensing, W. L., Fridley, B. L. & Hursting, S. D., Oct 1 2015, In: Cancer Prevention Research. 8, 10, p. 912-921 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    29 Scopus citations