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Guanming Wu

Associate Professor

Calculated based on number of publications stored in Pure and citations from Scopus
20032024

Research activity per year

Search results

  • 2020

    Genomic footprints of activated telomere maintenance mechanisms in cancer

    PCAWG Structural Variation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 733.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    69 Scopus citations

  • High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

    PCAWG Transcriptome Working Group, PCAWG Structural Variation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 736.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    45 Scopus citations

  • Integrative pathway enrichment analysis of multivariate omics data

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 735.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    93 Scopus citations

  • Pan-cancer analysis of whole genomes

    The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 82-93 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1537 Scopus citations

  • Pathway and network analysis of more than 2500 whole cancer genomes

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 729.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    62 Scopus citations

  • Perform pathway enrichment analysis using reactomeFIViz

    Haw, R., Loney, F., Ong, E., He, Y. & Wu, G., 2020, Methods in Molecular Biology. Humana Press Inc., p. 165-179 15 p. (Methods in Molecular Biology; vol. 2074).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    9 Scopus citations

  • Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

    MC3 Working Group, PCAWG novel somatic mutation calling methods working group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4748.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • Sex differences in oncogenic mutational processes

    PCAWG Tumour Subtypes and Clinical Translation & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4330.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations

  • The landscape of viral associations in human cancers

    PCAWG Pathogens & PCAWG Consortium, Mar 1 2020, In: Nature genetics. 52, 3, p. 320-330 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    218 Scopus citations

  • The reactome pathway knowledgebase

    Jassal, B., Matthews, L., Viteri, G., Gong, C., Lorente, P., Fabregat, A., Sidiropoulos, K., Cook, J., Gillespie, M., Haw, R., Loney, F., May, B., Milacic, M., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2020, In: Nucleic acids research. 48, D1, p. D498-D503

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1633 Scopus citations
  • 2019

    Acute myeloid leukemia–induced T-cell suppression can be reversed by inhibition of the MAPK pathway

    Moshofsky, K. B., Cho, H. J., Wu, G., Romine, K. A., Newman, M. T., Kosaka, Y., McWeeney, S. K. & Lind, E. F., Oct 22 2019, In: Blood Advances. 3, 20, p. 3038-3051 14 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    12 Scopus citations

  • Natural product target network reveals potential for cancer combination therapies

    Chamberlin, S. R., Blucher, A., Wu, G., Shinto, L., Choonoo, G., Kulesz-Martin, M. & McWeeney, S., 2019, In: Frontiers in Pharmacology. 10, MAY, 557.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations

  • Reactome and ORCID-fine-grained credit attribution for community curation

    Viteri, G., Matthews, L., Varusai, T., Gillespie, M., Milacic, M., Cook, J., Weiser, J., Shorser, S., Sidiropoulos, K., Fabregat, A., Haw, R., Wu, G., Stein, L., D'Eustachio, P. & Hermjakob, H., Jan 1 2019, In: Database : the journal of biological databases and curation. 2019

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • VIO: Ontology classification and study of vaccine responses given various experimental and analytical conditions

    Ong, E., Sun, P., Berke, K., Zheng, J., Wu, G. & He, Y., Dec 23 2019, In: BMC bioinformatics. 20, 704.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Visualization of drug target interactions in the contexts of pathways and networks with reactomefiviz

    Blucher, A. S., McWeeney, S. K., Stein, L. & Wu, G., 2019, In: F1000Research. 8, 908.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    17 Scopus citations
  • 2018

    Automation of ReactomeFIViz via CyREST API

    Wu, G. & Loney, F., 2018, In: F1000Research. 7, 531.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Network-based predictors of progression in head and neck squamous cell carcinoma

    Sanati, N., Iancu, O. D., Wu, G., Jacobs, J. E. & McWeeney, S. K., May 29 2018, In: Frontiers in Genetics. 9, MAY, 183.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Reactome graph database: Efficient access to complex pathway data

    Fabregat, A., Korninger, F., Viteri, G., Sidiropoulos, K., Marin-Garcia, P., Ping, P., Wu, G., Stein, L., D’Eustachio, P. & Hermjakob, H., Jan 2018, In: PLoS computational biology. 14, 1, e1005968.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    167 Scopus citations

  • The Reactome Pathway Knowledgebase

    Fabregat, A., Jupe, S., Matthews, L., Sidiropoulos, K., Gillespie, M., Garapati, P., Haw, R., Jassal, B., Korninger, F., May, B., Milacic, M., Roca, C. D., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Viteri, G., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2018, In: Nucleic acids research. 46, D1, p. D649-D655

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1752 Scopus citations
  • 2017

    Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

    Lewinsohn, D. A., Swarbrick, G. M., Park, B., Cansler, M. E., Null, M. D., Toren, K. G., Baseke, J., Zalwango, S., Mayanja-Kizza, H., Malone, L. L., Nyendak, M., Wu, G., Guinn, K., McWeeney, S., Mori, T., Chervenak, K. A., Sherman, D. R., Boom, W. H. & Lewinsohn, D. M., Dec 1 2017, In: npj Vaccines. 2, 1, 8.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    37 Scopus citations

  • Evidence-Based Precision Oncology with the Cancer Targetome

    Blucher, A. S., Choonoo, G., Kulesz-Martin, M., Wu, G. & McWeeney, S. K., Dec 2017, In: Trends in pharmacological sciences. 38, 12, p. 1085-1099 15 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    20 Scopus citations

  • Functional interaction network construction and analysis for disease discovery

    Wu, G. & Haw, R., 2017, Methods in Molecular Biology. Humana Press Inc., p. 235-253 19 p. (Methods in Molecular Biology; vol. 1558).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

    80 Scopus citations

  • Plant Reactome: A resource for plant pathways and comparative analysis

    Naithani, S., Preece, J., D'Eustachio, P., Gupta, P., Amarasinghe, V., Dharmawardhana, P. D., Wu, G., Fabregat, A., Elser, J. L., Weiser, J., Keays, M., Fuentes, A. M. P., Petryszak, R., Stein, L. D., Ware, D. & Jaiswal, P., Jan 1 2017, In: Nucleic acids research. 45, D1, p. D1029-D1039

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations
  • 2016

    Reactome from a WikiPathways Perspective

    Bohler, A., Wu, G., Kutmon, M., Pradhana, L. A., Coort, S. L., Hanspers, K., Haw, R., Pico, A. R. & Evelo, C. T., May 2016, In: PLoS computational biology. 12, 5, e1004941.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • The reactome pathway knowledgebase

    Fabregat, A., Sidiropoulos, K., Garapati, P., Gillespie, M., Hausmann, K., Haw, R., Jassal, B., Jupe, S., Korninger, F., McKay, S., Matthews, L., May, B., Milacic, M., Rothfels, K., Shamovsky, V., Webber, M., Weiser, J., Williams, M., Wu, G., Stein, L., & 2 othersHermjakob, H. & D'Eustachio, P., 2016, In: Nucleic acids research. 44, D1, p. D481-D487

    Research output: Contribution to journal › Article › peer-review

    Open Access
    978 Scopus citations
  • 2015

    Between pathways and networks lies context: Implications for precision medicine

    Laderas, T., Wu, G. & McWeeney, S., Sep 1 2015, In: Science Progress. 98, 3, p. 253-263 11 p.

    Research output: Contribution to journal › Article › peer-review

  • Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction

    Zhang, S., Chung, W. C., Wu, G., Egan, S. E., Miele, L. & Xu, K., May 15 2015, In: Cancer Research. 75, 10, p. 1936-1943 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations

  • Pathway and network analysis of cancer genomes

    Creixell, P., Reimand, J., Haider, S., Wu, G., Shibata, T., Vazquez, M., Mustonen, V., Gonzalez-Perez, A., Pearson, J., Sander, C., Raphael, B. J., Marks, D. S., Ouellette, B. F. F., Valencia, A., Bader, G. D., Boutros, P. C., Stuart, J. M., Linding, R., Lopez-Bigas, N. & Stein, L. D., Jun 30 2015, In: Nature Methods. 12, 7, p. 615-621 7 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
    242 Scopus citations
  • 2014

    A controlled vocabulary for pathway entities and events

    Jupe, S., Jassal, B., Williams, M. & Wu, G., 2014, In: Database. 2014

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • Gramene 2013: Comparative plant genomics resources

    Monaco, M. K., Stein, J., Naithani, S., Wei, S., Dharmawardhana, P., Kumari, S., Amarasinghe, V., Youens-Clark, K., Thomason, J., Preece, J., Pasternak, S., Olson, A., Jiao, Y., Lu, Z., Bolser, D., Kerhornou, A., Staines, D., Walts, B., Wu, G., D'Eustachio, P., & 6 othersHaw, R., Croft, D., Kersey, P. J., Stein, L., Jaiswal, P. & Ware, D., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D1193-D1199

    Research output: Contribution to journal › Article › peer-review

    Open Access
    149 Scopus citations

  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT consortium, Aug 7 2014, In: PLoS genetics. 10, 8, e1004517.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    166 Scopus citations

  • ReactomeFIViz: A cytoscape app for pathway and network-based data analysis

    Wu, G., Dawson, E., Duong, A., Haw, R. & Stein, L., Sep 12 2014, In: F1000Research. 3, 4431.2.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    173 Scopus citations

  • The Reactome pathway knowledgebase

    Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., Jassal, B., Jupe, S., Matthews, L., May, B., Palatnik, S., Rothfels, K., Shamovsky, V., Song, H., Williams, M., Birney, E., & 3 othersHermjakob, H., Stein, L. & D'Eustachio, P., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D472-D477

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1231 Scopus citations

  • Tumor-suppressive activity of lunatic fringe in prostate through differential modulation of notch receptor activation

    Zhang, S., Chung, W. C., Wu, G., Egan, S. E. & Xu, K., Feb 2014, In: Neoplasia (United States). 16, 2, p. 158-167 10 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    31 Scopus citations
  • 2013

    Network-Module-Based Approaches in Cancer Data Analysis

    Wu, G. & Stein, L., Apr 8 2013, Statistical Diagnostics for Cancer: Analyzing High-Dimensional Data. Wiley-VCH, Vol. 3. p. 173-192 20 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Systematic MicroRNA Analysis Identifies ATP6V0C as an Essential Host Factor for Human Cytomegalovirus Replication

    Pavelin, J., Reynolds, N., Chiweshe, S., Wu, G., Tiribassi, R. & Grey, F., 2013, In: PLoS pathogens. 9, 12, p. 1-13 13 p., e1003820.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    38 Scopus citations
  • 2012

    A genome-wide association search for type 2 diabetes genes in african americans

    DIAGRAM Consortium, MAGIC Investigators, Anders Hamsten on behalf of Procardis Consortium, DIAGRAM Consortium, GIANT Consortium, Global BPgen Consortium & for the MAGIC investigators, Jan 4 2012, In: PloS one. 7, 1, e29202.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    142 Scopus citations

  • A network module-based method for identifying cancer prognostic signatures

    Wu, G. & Stein, L., 2012, In: Genome biology. 13, 12, p. R112

    Research output: Contribution to journal › Article › peer-review

    Open Access
    125 Scopus citations

  • Annotating cancer variants and anti-cancer therapeutics in Reactome

    Milacic, M., Haw, R., Rothfels, K., Wu, G., Croft, D., Hermjakob, H., D'Eustachio, P. & Stein, L., Dec 2012, In: Cancers. 4, 4, p. 1180-1211 32 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    233 Scopus citations
  • 2011

    Abdominal aortic aneurysm is associated with a variant in low-density lipoprotein receptor-related protein 1

    Bown, M. J., Jones, G. T., Harrison, S. C., Wright, B. J., Bumpstead, S., Baas, A. F., Gretarsdottir, S., Badger, S. A., Bradley, D. T., Burnand, K., Child, A. H., Clough, R. E., Cockerill, G., Hafez, H., Scott, D. J. A., Futers, S., Johnson, A., Sohrabi, S., Smith, A., Thompson, M. M., & 461 othersvan Bockxmeer, F. M., Waltham, M., Matthiasson, S. E., Thorleifsson, G., Thorsteinsdottir, U., Blankensteijn, J. D., Teijink, J. A. W., Wijmenga, C., de Graaf, J., Kiemeney, L. A., Assimes, T. L., McPherson, R., Folkersen, L., Franco-Cereceda, A., Palmen, J., Smith, A. J., Sylvius, N., Wild, J. B., Refstrup, M., Edkins, S., Gwilliam, R., Hunt, S. E., Potter, S., Lindholt, J. S., Frikke-Schmidt, R., Tybjærg-Hansen, A., Hughes, A. E., Golledge, J., Norman, P. E., van Rij, A., Powell, J. T., Eriksson, P., Stefansson, K., Thompson, J. R., Humphries, S. E., Sayers, R. D., Deloukas, P., Samani, N. J., Schunkert, H., König, I. R., Kathiresan, S., Reilly, M. P., Holm, H., Preuss, M., Stewart, A. F. R., Barbalic, M., Gieger, C., Absher, D., Aherrahrou, Z., Allayee, H., Altshuler, D., Anand, S. S., Andersen, K., Anderson, J. L., Ardissino, D., Ball, S. G., Balmforth, A. J., Barnes, T. A., Becker, D. M., Becker, L. C., Berger, K., Bis, J. C., Matthijs Boekholdt, S., Boerwinkle, E., Braund, P. S., Susan Burnett, M., Buysschaert, I., Carlquist, J. F., Chen, L., Cichon, S., Codd, V., Davies, R. W., Dedoussis, G., Dehghan, A., Demissie, S., Devaney, J. M., Diemert, P., Do, R., Doering, A., Eifert, S., El Mokhtari, N. E., Ellis, S. G., Elosua, R., Engert, J. C., Epstein, S. E., de Faire, U., Fischer, M., Folsom, A. R., Freyer, J., Gigante, B., Girelli, D., Gudnason, V., Gulcher, J. R., Halperin, E., Hammond, N., Hazen, S. L., Hofman, A., Horne, B. D., Illig, T., Iribarren, C., Wouter Jukema, J., Kaiser, M. A., Kaplan, L. M., Kastelein, J. J. P., Khaw, K. T., Knowles, J. W., Kolovou, G., Kong, A., Laaksonen, R., Lambrechts, D., Leander, K., Lettre, G., Li, M., Lieb, W., Loley, C., Lotery, A. J., Mannucci, P. M., Maouche, S., Martinelli, N., McKeown, P. P., Meisinger, C., Meitinger, T., Melander, O., Angelica Merlini, P., Mooser, V., Morgan, T., Mühleisen, T. W., Muhlestein, J. B., Münzel, T., Musunuru, K., Nahrstaedt, J., Nelson, C. P., Nöthen, M. M., Olivieri, O., Patel, R. S., Patterson, C. C., Peters, A., Peyvandi, F., Qu, L., Quyyumi, A. A., Rader, D. J., Rallidis, L. S., Rice, C., Rosendaal, F. R., Rubin, D., Salomaa, V., Lourdes Sampietro, M., Sandhu, M. S., Schadt, E., Schäfer, A., Schillert, A., Schreiber, S., Schrezenmeir, J., Schwartz, S. M., Siscovick, D. S., Sivananthan, M., Sivapalaratnam, S., Smith, T. B., Snoep, J. D., Soranzo, N., Spertus, J. A., Stark, K., Stirrups, K., Stoll, M., Wilson Tang, W. H., Tennstedt, S., Thorgeirsson, G., Tomaszewski, M., van Rij, A. M., Voight, B. F., Wareham, N. J., Wells, G. A., Wichmann, H. E., Wild, P. S., Willenborg, C., Witteman, J. C. M., Ye, S., Zeller, T., Ziegler, A., Cambien, F., Goodall, A. H., Adrienne Cupples, L., Quertermous, T., März, W., Hengstenberg, C., Blankenberg, S., Ouwehand, W. H., Hall, A. S., Roberts, R., O'Donnell, C. J., Erdmann, J., Newton-Cheh, C., Johnson, T., Gateva, V., Tobin, M. D., Bochud, M., Coin, L., Najjar, S. S., Hua Zhao, J., Heath, S. C., Eyheramendy, S., Papadakis, K., Scott, L. J., Zhang, F., Farrall, M., Tanaka, T., Wallace, C., Chambers, J. C., Nilsson, P., van der Harst, P., Polidoro, S., Grobbee, D. E., Onland-Moret, N. C., Bots, M. L., Wain, L. V., Elliott, K. S., Teumer, A., Luan, J., Lucas, G., Kuusisto, J., Burton, P. R., Hadley, D., McArdle, W. L., Brown, M., Dominiczak, A., Newhouse, S. J., Webster, J., Zeggini, E., Beckmann, J. S., Lim, N., Song, K., Vollenweider, P., Waeber, G., Waterworth, D. M., Yuan, X., Groop, L., Orho-Melander, M., Allione, A., Di Gregorio, A., Guarrera, S., Panico, S., Ricceri, F., Romanazzi, V., Sacerdote, C., Vineis, P., Barroso, I., Luben, R. N., Crawford, G. J., Jousilahti, P., Perola, M., Boehnke, M., Bonnycastle, L. L., Jackson, A. U., Mohlke, K. L., Stringham, H. M., Valle, T. T., Willer, C. J., Bergman, R. N., Morken, M. A., Döring, A., Org, E., Pfeufer, A., Marrugat, J., Subirana, I., Freimer, N. B., Hartikainen, A. L., McCarthy, M. I., O'Reilly, P. F., Peltonen, L., Pouta, A., de Jong, P. E., Snieder, H., van Gilst, W. H., Clarke, R., Goel, A., Hamsten, A., Peden, J. F., Seedorf, U., Syvänen, A. C., Tognoni, G., Lakatta, E. G., Sanna, S., Scheet, P., Schlessinger, D., Scuteri, A., Dörr, M., Ernst, F., Felix, S. B., Homuth, G., Lorbeer, R., Reffelmann, T., Rettig, R., Völker, U., Galan, P., Gut, I. G., Hercberg, S., Mark Lathrop, G., Zelenika, D., Williams, F. M., Zhai, G., Laakso, M., Forouhi, N. G., Völzke, H., Uiterwaal, C. S., van der Schouw, Y. T., Numans, M. E., Matullo, G., Navis, G., Berglund, G., Bingham, S. A., Kooner, J. S., Connell, J. M., Bandinelli, S., Ferrucci, L., Watkins, H., Spector, T. D., Tuomilehto, J., Strachan, D. P., Laan, M., Meneton, P., Uda, M., Jarvelin, M. R., Loos, R. J. F., Elliott, P., Abecasis, G. R., Caulfield, M., Munroe, P. B., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Huth, C., Aulchenko, Y. S., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M., Dupuis, J., Qi, L., Segrè, A. V., van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Bengtsson Boström, K., Bravenboer, B., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, A. L., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Johnson, P. R. V., Jørgensen, T., Kao, W. H. L., Klopp, N., Kraft, P., Lauritzen, T., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Midthjell, K., Narisu, N., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proença, C., Prokopenko, I., Rathmann, W., William Rayner, N., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsø, T., Strassburger, K., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., van Dam, R. M., van Haeften, T. W., van Herpt, T., van Vliet-Ostaptchouk, J. V., Bragi Walters, G., Weedon, M. N., Cauchi, S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hunter, D. J., Hveem, K., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Uitterlinden, A., Walker, M., Watanabe, R. M., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Florez, J. C., Frayling, T. M., Sladek, R., Wilson, J. F., Froguel, P., van Duijn, C. M., Blair, R. D., Hill, A. A., Gerry Hill, B., Lewis, D. R., McNoe, L. A., Merriman, T. R., Naik, D. K., Vicky Phillips, L., Thomson, I. A., Topless, R., Vasudevan, T. M. & Yu, G., Nov 11 2011, In: American Journal of Human Genetics. 89, 5, p. 619-627 9 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    155 Scopus citations

  • Erratum: Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

    Voight, B. F., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., McCulloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Langenberg, C., Hofmann, O. M., & 138 othersDupuis, J., Qi, L., Segŕ, A. V., Van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bostrám, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Fox, C. S., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Isomaa, B., Jackson, A. U., Johnson, P. R. V., J́rgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Kuusisto, J., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Narisu, N., Nilsson, P., Owen, K. R., Payne, F., Perry, J. R. B., Petersen, A. K., Platou, C., Proeńa, C., Prokopenko, I., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparsa̧, T., Strassburger, K., Stringham, H. M., Sun, Q., Swift, A. J., Thorand, B., Tichet, J., Tuomi, T., Van Dam, R. M., Van Haeften, T. W., Van Herpt, T., Van Vliet-Ostaptchouk, J. V., Walters, G. B., Weedon, M. N., Wijmenga, C., Witteman, J., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A., Walker, M., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Florez, J. C., Frayling, T. M., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M. & McCarthy, M. I., Feb 2011, In: Nature genetics. 43, 4, p. 388 1 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    5 Scopus citations

  • Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

    Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J. R., Travers, M. E., Bouatia-Naji, N., Dimas, A. S., Nica, A. C., Wheeler, E., Chen, H., Voight, B. F., Taneera, J., Kanoni, S., Peden, J. F., Turrini, F., Gustafsson, S., Zabena, C., & 670 othersAlmgren, P., Barker, D. J. P., Barnes, D., Dennison, E. M., Eriksson, J. G., Eriksson, P., Eury, E., Folkersen, L., Fox, C. S., Frayling, T. M., Goel, A., Gu, H. F., Horikoshi, M., Isomaa, B., Jackson, A. U., Jameson, K. A., Kajantie, E., Kerr-Conte, J., Kuulasmaa, T., Kuusisto, J., Loos, R. J. F., Luan, J., Makrilakis, K., Manning, A. K., Martínez-Larrad, M. T., Narisu, N., Mannila, M. N., Öhrvik, J., Osmond, C., Pascoe, L., Payne, F., Sayer, A. A., Sennblad, B., Silveira, A., Stančcáková, A., Stirrups, K., Swift, A. J., Syvänen, A. C., Tuomi, T., Van't Hooft, F. M., Walker, M., Weedon, M. N., Xie, W., Zethelius, B., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., Mcculloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Hofmann, O. M., Qi, L., Segre, A. V., Van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bostrom, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Johnson, P. R. V., Jorgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Nilsson, P., Owen, K. R., Perry, J. R. B., Petersen, A. K., Platou, C., Proenca, C., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparso, T., Strassburger, K., Stringham, H. M., Sun, Q., Thorand, B., Tichet, J., Van Dam, R. M., Van Haeften, T. W., Van Herpt, T., Van Vliet-Ostaptchouk, J. V., Walters, G. B., Wijmenga, C., Witteman, J. C. M., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A. G., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M., McCarthy, M. I., Speliotes, E. K., Berndt, S. I., Monda, K. L., Allen, H. L., Magi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Workalemahu, T., Heid, I. M., Wood, A. R., Weyant, R. J., Estrada, K., Liang, L., Nemesh, J., Park, J. H., Kilpelainen, T. O., Yang, J., Esko, T., Feitosa, M. F., Kutalik, Z., Mangino, M., Scherag, A., Smith, A. V., Zhao, J. H., Aben, K. K., Absher, D. M., Dixon, A. L., Fisher, E., Glazer, N. L., Goddard, M. E., Heard-Costa, N. L., Hoesel, V., Hottenga, J. J., Johansson, A., Johnson, T., Ketkar, S., Lamina, C., Li, S., Moffatt, M. F., Myers, R. H., Peters, M. J., Preuss, M., Ripatti, S., Rivadeneira, F., Sandholt, C., Timpson, N. J., Tyrer, J. P., Van Wingerden, S., White, C. C., Wiklund, F., Barlassina, C., Chasman, D. I., Cooper, M. N., Jansson, J. O., Lawrence, R. W., Pellikka, N., Shi, J., Thiering, E., Alavere, H., Alibrandi, M. T. S., Arnold, A. M., Aspelund, T., Atwood, L. D., Balmforth, A. 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R., Frossard, P., Danesh, J., Östenson, C. G., Lind, L., Cooper, C. C., Serrano-Ríos, M., Ferrannini, E., Forsen, T. J., Pattou, F., Langenberg, C., Hamsten, A. & Florez, J. C., Oct 1 2011, In: Diabetes. 60, 10, p. 2624-2634 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    289 Scopus citations

  • Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

    Sawey, E. T., Chanrion, M., Cai, C., Wu, G., Zhang, J., Zender, L., Zhao, A., Busuttil, R. W., Yee, H., Stein, L., French, D. M., Finn, R. S., Lowe, S. W. & Powers, S., Mar 8 2011, In: Cancer Cell. 19, 3, p. 347-358 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    349 Scopus citations

  • PSICQUIC and PSISCORE: Accessing and scoring molecular interactions

    Aranda, B., Blankenburg, H., Kerrien, S., Brinkman, F. S. L., Ceol, A., Chautard, E., Dana, J. M., De Las Rivas, J., Dumousseau, M., Galeota, E., Gaulton, A., Goll, J., Hancock, R. E. W., Isserlin, R., Jimenez, R. C., Kerssemakers, J., Khadake, J., Lynn, D. J., Michaut, M., O'Kelly, G., & 20 othersOno, K., Orchard, S., Prieto, C., Razick, S., Rigina, O., Salwinski, L., Simonovic, M., Velankar, S., Winter, A., Wu, G., Bader, G. D., Cesareni, G., Donaldson, I. M., Eisenberg, D., Kleywegt, G. J., Overington, J., Ricard-Blum, S., Tyers, M., Albrecht, M. & Hermjakob, H., Jul 2011, In: Nature Methods. 8, 7, p. 528-529 2 p.

    Research output: Contribution to journal › Letter › peer-review

    Open Access
    216 Scopus citations

  • Reactome: A database of reactions, pathways and biological processes

    Croft, D., O'Kelly, G., Wu, G., Haw, R., Gillespie, M., Matthews, L., Caudy, M., Garapati, P., Gopinath, G., Jassal, B., Jupe, S., Kalatskaya, I., MayMahajan, S., May, B., Ndegwa, N., Schmidt, E., Shamovsky, V., Yung, C., Birney, E., Hermjakob, H., & 2 othersD'Eustachio, P. & Stein, L., Jan 2011, In: Nucleic acids research. 39, SUPPL. 1, p. D691-D697

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1203 Scopus citations
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    A human functional protein interaction network and its application to cancer data analysis

    Wu, G., Feng, X. & Stein, L., May 19 2010, In: Genome biology. 11, 5, R53.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    508 Scopus citations

  • A viral microRNA down-regulates multiple cell cycle genes through mRNA 59′UTRs

    Grey, F., Tirabassi, R., Meyers, H., Wu, G., McWeeney, S., Hook, L. & Nelson, J., Jun 2010, In: PLoS pathogens. 6, 6

    Research output: Contribution to journal › Article › peer-review

    Open Access
    176 Scopus citations

  • Erratum: The BioPAX community standard for pathway data sharing (Nat. Biotechnol. (2010) 28 (935-942)

    Demir, E., Paley, S., Fukuda, K., Lemer, C., Vastrik, I., Wu, G., D'Eustachio, P., Schaefer, C., Luciano, J., Schacherer, F., Martinez-Flores, I., Hu, Z., Jimenez-Jacinto, V., Joshi-Tope, G., Kandasamy, K., Lopez-Fuentes, A. C., Mi, H., Pichler, E., Rodchenkov, I., Splendiani, A., & 69 othersTkachev, S., Zucker, J., Gopinath, G., Rajasimha, H., Ramakrishnan, R., Shah, I., Syed, M., Anwar, N., Babur, O., Blinov, M., Brauner, E., Corwin, D., Donaldson, S., Gibbons, F., Goldberg, R., Hornbeck, P., Luna, A., Murray-Rust, P., Neumann, E., Reubenacker, O., Samwald, M., Van Iersel, M., Wimalaratne, S., Allen, K., Braun, B., Whirl-Carrillo, M., Cheung, K. H., Dahlquist, K., Finney, A., Gillespie, M., Glass, E., Gong, L., Haw, R., Honig, M., Hubaut, O., Kane, D., Krupa, S., Kutmon, M., Leonard, J., Marks, D., Merberg, D., Petri, V., Pico, A., Ravenscroft, D., Ren, L., Shah, N., Sunshine, M., Tang, R., Whaley, R., Letovksy, S., Buetow, K. H., Rzhetsky, A., Schachter, V., Sobral, B. S., Dogrusoz, U., McWeeney, S., Aladjem, M., Birney, E., Collado-Vides, J., Goto, S., Hucka, M., Novère, N. L., Maltsev, N., Pandey, A., Thomas, P., Wingender, E., Karp, P. D., Sander, C. & Bader, G. D., Dec 2010, In: Nature biotechnology. 28, 12, p. 1308 1 p.

    Research output: Contribution to journal › Comment/debate › peer-review

    Open Access
    3 Scopus citations

  • The BioPAX community standard for pathway data sharing

    Demir, E., Cary, M. P., Paley, S., Fukuda, K., Lemer, C., Vastrik, I., Wu, G., D'Eustachio, P., Schaefer, C., Luciano, J., Schacherer, F., Martinez-Flores, I., Hu, Z., Jimenez-Jacinto, V., Joshi-Tope, G., Kandasamy, K., Lopez-Fuentes, A. C., Mi, H., Pichler, E., Rodchenkov, I., & 70 othersSplendiani, A., Tkachev, S., Zucker, J., Gopinath, G., Rajasimha, H., Ramakrishnan, R., Shah, I., Syed, M., Anwar, N., Babur, Ö., Blinov, M., Brauner, E., Corwin, D., Donaldson, S., Gibbons, F., Goldberg, R., Hornbeck, P., Luna, A., Murray-Rust, P., Neumann, E., Reubenacker, O., Samwald, M., Van Iersel, M., Wimalaratne, S., Allen, K., Braun, B., Whirl-Carrillo, M., Cheung, K. H., Dahlquist, K., Finney, A., Gillespie, M., Glass, E., Gong, L., Haw, R., Honig, M., Hubaut, O., Kane, D., Krupa, S., Kutmon, M., Leonard, J., Marks, D., Merberg, D., Petri, V., Pico, A., Ravenscroft, D., Ren, L., Shah, N., Sunshine, M., Tang, R., Whaley, R., Letovksy, S., Buetow, K. H., Rzhetsky, A., Schachter, V., Sobral, B. S., Dogrusoz, U., McWeeney, S., Aladjem, M., Birney, E., Collado-Vides, J., Goto, S., Hucka, M., Novère, N. L., Maltsev, N., Pandey, A., Thomas, P., Wingender, E., Karp, P. D., Sander, C. & Bader, G. D., Sep 2010, In: Nature biotechnology. 28, 9, p. 935-942 8 p.

    Research output: Contribution to journal › Review article › peer-review

    Open Access
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  • Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

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