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Guanming Wu

Associate Professor

Calculated based on number of publications stored in Pure and citations from Scopus
20032024

Research activity per year

Search results

  • Article

    A viral microRNA down-regulates multiple cell cycle genes through mRNA 59′UTRs

    Grey, F., Tirabassi, R., Meyers, H., Wu, G., McWeeney, S., Hook, L. & Nelson, J., Jun 2010, In: PLoS pathogens. 6, 6

    Research output: Contribution to journal › Article › peer-review

    Open Access
    176 Scopus citations

  • Between pathways and networks lies context: Implications for precision medicine

    Laderas, T., Wu, G. & McWeeney, S., Sep 1 2015, In: Science Progress. 98, 3, p. 253-263 11 p.

    Research output: Contribution to journal › Article › peer-review

  • Biology-inspired graph neural network encodes reactome and reveals biochemical reactions of disease

    Burkhart, J. G., Wu, G., Song, X., Raimondi, F., McWeeney, S., Wong, M. H. & Deng, Y., Jul 14 2023, In: Patterns. 4, 7, 100758.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    2 Scopus citations

  • Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

    PCAWG Drivers and Functional Interpretation Group & PCAWG Consortium, Dec 1 2020, In: Communications Biology. 3, 1, 56.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    132 Scopus citations

  • CIDO ontology updates and secondary analysis of host responses to COVID-19 infection based on ImmPort reports and literature

    Huffman, A., Masci, A. M., Zheng, J., Sanati, N., Brunson, T., Wu, G. & He, Y., Dec 2021, In: Journal of Biomedical Semantics. 12, 1, 18.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    8 Scopus citations

  • Circulating Neoplastic-Immune Hybrid Cells Predict Metastatic Progression in Uveal Melanoma

    Parappilly, M. S., Chin, Y., Whalen, R. M., Anderson, A. N., Robinson, T. S., Strgar, L., Sutton, T. L., Conley, P., Klocke, C., Gibbs, S. L., Chang, Y. H., Wu, G., Wong, M. H. & Skalet, A. H., Oct 2022, In: Cancers. 14, 19, 4617.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    7 Scopus citations

  • Clonal hematopoiesis related TET2 loss-of-function impedes IL1β-mediated epigenetic reprogramming in hematopoietic stem and progenitor cells

    McClatchy, J., Strogantsev, R., Wolfe, E., Lin, H. Y., Mohammadhosseini, M., Davis, B. A., Eden, C., Goldman, D., Fleming, W. H., Conley, P., Wu, G., Cimmino, L., Mohammed, H. & Agarwal, A., Dec 2023, In: Nature communications. 14, 1, 8102.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Combined burden and functional impact tests for cancer driver discovery using DriverPower

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 734.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    25 Scopus citations

  • Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing

    PCAWG Structural Variation Working Group & PCAWG Consortium, Mar 1 2020, In: Nature genetics. 52, 3, p. 331-341 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    352 Scopus citations

  • Comprehensive definition of human immunodominant CD8 antigens in tuberculosis

    Lewinsohn, D. A., Swarbrick, G. M., Park, B., Cansler, M. E., Null, M. D., Toren, K. G., Baseke, J., Zalwango, S., Mayanja-Kizza, H., Malone, L. L., Nyendak, M., Wu, G., Guinn, K., McWeeney, S., Mori, T., Chervenak, K. A., Sherman, D. R., Boom, W. H. & Lewinsohn, D. M., Dec 1 2017, In: npj Vaccines. 2, 1, 8.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    38 Scopus citations

  • Comprehensive molecular characterization of mitochondrial genomes in human cancers

    PCAWG Consortium, Mar 1 2020, In: Nature genetics. 52, 3, p. 342-352 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    210 Scopus citations

  • COVID19 Disease Map, a computational knowledge repository of virus–host interaction mechanisms

    the COVID-19 Disease Map Community, Oct 2021, In: Molecular Systems Biology. 17, 10, e10387.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations

  • Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

    PCAWG Structural Variation Working Group & PCAWG Consortium, Mar 1 2020, In: Nature genetics. 52, 3, p. 294-305 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    145 Scopus citations

  • Divergent mutational processes distinguish hypoxic and normoxic tumours

    PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 737.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    79 Scopus citations

  • Drug-target identification in COVID-19 disease mechanisms using computational systems biology approaches

    the COVID-19 Disease Map Community, 2023, In: Frontiers in immunology. 14, 1282859.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

    Strawbridge, R. J., Dupuis, J., Prokopenko, I., Barker, A., Ahlqvist, E., Rybin, D., Petrie, J. R., Travers, M. E., Bouatia-Naji, N., Dimas, A. S., Nica, A. C., Wheeler, E., Chen, H., Voight, B. F., Taneera, J., Kanoni, S., Peden, J. F., Turrini, F., Gustafsson, S., Zabena, C., & 670 othersAlmgren, P., Barker, D. J. P., Barnes, D., Dennison, E. M., Eriksson, J. G., Eriksson, P., Eury, E., Folkersen, L., Fox, C. S., Frayling, T. M., Goel, A., Gu, H. F., Horikoshi, M., Isomaa, B., Jackson, A. U., Jameson, K. A., Kajantie, E., Kerr-Conte, J., Kuulasmaa, T., Kuusisto, J., Loos, R. J. F., Luan, J., Makrilakis, K., Manning, A. K., Martínez-Larrad, M. T., Narisu, N., Mannila, M. N., Öhrvik, J., Osmond, C., Pascoe, L., Payne, F., Sayer, A. A., Sennblad, B., Silveira, A., Stančcáková, A., Stirrups, K., Swift, A. J., Syvänen, A. C., Tuomi, T., Van't Hooft, F. M., Walker, M., Weedon, M. N., Xie, W., Zethelius, B., Scott, L. J., Steinthorsdottir, V., Morris, A. P., Dina, C., Welch, R. P., Zeggini, E., Huth, C., Aulchenko, Y. S., Thorleifsson, G., Mcculloch, L. J., Ferreira, T., Grallert, H., Amin, N., Wu, G., Willer, C. J., Raychaudhuri, S., McCarroll, S. A., Hofmann, O. M., Qi, L., Segre, A. V., Van Hoek, M., Navarro, P., Ardlie, K., Balkau, B., Benediktsson, R., Bennett, A. J., Blagieva, R., Boerwinkle, E., Bonnycastle, L. L., Bostrom, K. B., Bravenboer, B., Bumpstead, S., Burtt, N. P., Charpentier, G., Chines, P. S., Cornelis, M., Couper, D. J., Crawford, G., Doney, A. S. F., Elliott, K. S., Elliott, A. L., Erdos, M. R., Franklin, C. S., Ganser, M., Gieger, C., Grarup, N., Green, T., Griffin, S., Groves, C. J., Guiducci, C., Hadjadj, S., Hassanali, N., Herder, C., Johnson, P. R. V., Jorgensen, T., Kao, W. H. L., Klopp, N., Kong, A., Kraft, P., Lauritzen, T., Li, M., Lieverse, A., Lindgren, C. M., Lyssenko, V., Marre, M., Meitinger, T., Midthjell, K., Morken, M. A., Nilsson, P., Owen, K. R., Perry, J. R. B., Petersen, A. K., Platou, C., Proenca, C., Rathmann, W., Rayner, N. W., Robertson, N. R., Rocheleau, G., Roden, M., Sampson, M. J., Saxena, R., Shields, B. M., Shrader, P., Sigurdsson, G., Sparso, T., Strassburger, K., Stringham, H. M., Sun, Q., Thorand, B., Tichet, J., Van Dam, R. M., Van Haeften, T. W., Van Herpt, T., Van Vliet-Ostaptchouk, J. V., Walters, G. B., Wijmenga, C., Witteman, J. C. M., Bergman, R. N., Cauchi, S., Collins, F. S., Gloyn, A. L., Gyllensten, U., Hansen, T., Hide, W. A., Hitman, G. A., Hofman, A., Hunter, D. J., Hveem, K., Laakso, M., Mohlke, K. L., Morris, A. D., Palmer, C. N. A., Pramstaller, P. P., Rudan, I., Sijbrands, E., Stein, L. D., Tuomilehto, J., Uitterlinden, A. G., Wareham, N. J., Watanabe, R. M., Abecasis, G. R., Boehm, B. O., Campbell, H., Daly, M. J., Hattersley, A. T., Hu, F. B., Meigs, J. B., Pankow, J. S., Pedersen, O., Wichmann, H. E., Barroso, I., Groop, L., Sladek, R., Thorsteinsdottir, U., Wilson, J. F., Illig, T., Froguel, P., Van Duijn, C. M., Stefansson, K., Altshuler, D., Boehnke, M., McCarthy, M. I., Speliotes, E. K., Berndt, S. I., Monda, K. L., Allen, H. L., Magi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Workalemahu, T., Heid, I. M., Wood, A. R., Weyant, R. J., Estrada, K., Liang, L., Nemesh, J., Park, J. H., Kilpelainen, T. O., Yang, J., Esko, T., Feitosa, M. F., Kutalik, Z., Mangino, M., Scherag, A., Smith, A. V., Zhao, J. H., Aben, K. K., Absher, D. M., Dixon, A. L., Fisher, E., Glazer, N. L., Goddard, M. E., Heard-Costa, N. L., Hoesel, V., Hottenga, J. J., Johansson, A., Johnson, T., Ketkar, S., Lamina, C., Li, S., Moffatt, M. F., Myers, R. H., Peters, M. J., Preuss, M., Ripatti, S., Rivadeneira, F., Sandholt, C., Timpson, N. J., Tyrer, J. P., Van Wingerden, S., White, C. C., Wiklund, F., Barlassina, C., Chasman, D. I., Cooper, M. N., Jansson, J. O., Lawrence, R. W., Pellikka, N., Shi, J., Thiering, E., Alavere, H., Alibrandi, M. T. S., Arnold, A. M., Aspelund, T., Atwood, L. D., Balmforth, A. J., Ben-Shlomo, Y., Bergmann, S., Biebermann, H., Blakemore, A. I. F., Boes, T., Bornstein, S. R., Brown, M. J., Buchanan, T. A., Busonero, F., Cappuccio, F. P., Cavalcanti-Proenca, C., Chen, Y. D. I., Chen, C. M., Clarke, R., Coin, L., Connell, J., Day, I. N. M., Den Heijer, M., Duan, J., Ebrahim, S., Elliott, P., Elosua, R., Eiriksdottir, G., Facheris, M. F., Felix, S. B., Fischer-Posovszky, P., Folsom, A. R., Friedrich, N., Freimer, N. B., Fu, M., Gaget, S., Gejman, P. V., Geus, E. J. C., Gjesing, A. P., Goyette, P., Grasler, J., Greenawalt, D. M., Gudnason, V., Hartikainen, A. L., Hall, A. S., Havulinna, A. S., Hayward, C., Heath, A. C., Hengstenberg, C., Hicks, A. A., Hinney, A., Homuth, G., Hui, J., Igl, W., Iribarren, C., Jacobs, K. B., Jarick, I., Jewell, E., John, U., Jousilahti, P., Jula, A., Kaakinen, M., Kaplan, L. M., Kathiresan, S., Kettunen, J., Kinnunen, L., Knowles, J. W., Kolcic, I., König, I. R., Koskinen, S., Kovacs, P., Kvaloy, K., Laitinen, J., Lantieri, O., Lanzani, C., Launer, L. J., Lecoeur, C., Lehtimaki, T., Lettre, G., Liu, J., Lokki, M. L., Lorentzon, M., Luben, R. N., Ludwig, B., Manunta, P., Marek, D., Martin, N. G., McArdle, W. L., McCarthy, A., McKnight, B., Melander, O., Meyre, D., Montgomery, G. W., Mulic, R., Ngwa, J. S., Nelis, M., Neville, M. J., Nyholt, D. R., O'Donnell, C. J., O'Rahilly, S., Ong, K. K., Oostra, B., Pare, G., Parker, A. N., Perola, M., Pichler, I., Pietilainen, K. H., Platou, C. G. P., Polasek, O., Pouta, A., Rafelt, S., Raitakari, O., Rayner, N. W., Ridderstrale, M., Rief, W., Ruokonen, A., Rzehak, P., Salomaa, V., Sanders, A. R., Sandhu, M. S., Sanna, S., Saramies, J., Savolainen, M. J., Scherag, S., Schipf, S., Schreiber, S., Schunkert, H., Silander, K., Sinisalo, J., Siscovick, D. S., Smit, J. H., Soranzo, N., Sovio, U., Stephens, J., Surakka, I., Tammesoo, M. L., Tardif, J. C., Teder-Laving, M., Teslovich, T. M., Thompson, J. R., Thomson, B., Tonjes, A., Van Meurs, J. B. J., Van Ommen, G. J., Vatin, V., Viikari, J., Visvikis-Siest, S., Vitart, V., Vogel, C. I. G., Waite, L. L., Wallaschofski, H., Widen, E., Wiegand, S., Wild, S. H., Willemsen, G., Witte, D. R., Xu, J., Zhang, Q., Zgaga, L., Ziegler, A., Zitting, P., Beilby, J. P., Farooqi, I. S., Hebebrand, J., Huikuri, H. V., James, A. L., Kahonen, M., Levinson, D. F., Macciardi, F., Nieminen, M. S., Ohlsson, C., Palmer, L. J., Ridker, P. M., Stumvoll, M., Beckmann, J. S., Boeing, H., Boomsma, D. I., Caulfield, M. J., Chanock, S. J., Cupples, L. A., Smith, G. D., Erdmann, J., Gronberg, H., Hall, P., Harris, T. B., Hayes, R. B., Heinrich, J., Jarvelin, M. R., Kaprio, J., Karpe, F., Khaw, K. T., Kiemeney, L. A., Krude, H., Lawlor, D. A., Metspalu, A., Munroe, P. B., Ouwehand, W. H., Penninx, B. W., Peters, A., Quertermous, T., Reinehr, T., Rissanen, A., Samani, N. J., Schwarz, P. E. H., Shuldiner, A. R., Spector, T. D., Uda, M., Valle, T. T., Wabitsch, M., Waeber, G., Watkins, H., Wright, A. F., Zillikens, M. C., Chatterjee, N., Purcell, S., Schadt, E. E., Visscher, P. M., Assimes, T. L., Borecki, I. B., Deloukas, P., Haritunians, T., Kaplan, R. C., O'Connell, J. R., Peltonen, L., Schlessinger, D., Strachan, D. P., North, K. E., Hirschhorn, J. N., Ingelsson, E., Parts, L., Glass, D., Nisbet, J., Barrett, A., Sekowska, M., Potter, S., Grundberg, E., Small, K., Hedman, A. K., Bataille, V., Bell, J. T., Surdulescu, G., Ingle, C., Nestle, F. O., Di Meglio, P., Min, J. L., Wilk, A., Hammond, C. J., Yang, T. P., Montgomery, S. B., Zondervan, K. T., Durbin, R., Ahmadi, K., Dermitzakis, E. T., Reilly, M. P., Holm, H., Stewart, A. F. R., Barbalic, M., Aherrahrou, Z., Allayee, H., Anand, S. S., Andersen, K., Anderson, J. L., Ardissino, D., Ball, S. G., Barnes, T. A., Becker, D. M., Becker, L. C., Berger, K., Bis, J. C., Boekholdt, S. M., Braund, P. S., Burnett, M. S., Buysschaert, I., Carlquist, J. F., Chen, L., Codd, V., Davies, R. W., Cichon, S., Dedoussis, G. V., Demissie, S., Dehghan, A., Devaney, J. M., Diemert, P., Do, R., Doering, A., Eifert, S., El Mokhtari, N. E., Ellis, S. G., Engert, J. C., Epstein, S. E., De Faire, U., Fischer, M., Freyer, J., Gigante, B., Girelli, D., Gretarsdottir, S., Gulcher, J. R., Halperin, E., Hammond, N., Hazen, S. L., Horne, B. D., Jones, G. T., Jukema, J. W., Kaiser, M. A., Kastelein, J. J. P., Kolovou, G., Laaksonen, R., Lambrechts, D., Leander, K., Li, M., Lieb, W., Loley, C., Lotery, A. J., Mannucci, P. M., Maouche, S., Martinelli, N., McKeown, P. P., Meisinger, C., Merlini, P. A., Mooser, V., Morgan, T., Mühleisen, T. W., Muhlestein, J. B., Münzel, T., Musunuru, K., Nahrstaedt, J., Nelson, C. P., Nöthen, M. M., Olivieri, O., Patel, R. S., Patterson, C. C., Peyvandi, F., Qu, L., Quyyumi, A. A., Rader, D. J., Rallidis, L. S., Rice, C., Rosendaal, F. R., Rubin, D., Sampietro, M. L., Sandhu, M. S., Schäfer, A., Schillert, A., Schrezenmeir, J., Schwartz, S. M., Sivananthan, M., Sivapalaratnam, S., Smith, T. B., Snoep, J. D., Spertus, J. A., Stark, K., Stoll, M., Wilson Tang, W. H., Tennstedt, S., Thorgeirsson, G., Tomaszewski, M., Van Rij, A. M., Wells, G. A., Wild, P. S., Willenborg, C., Wright, B. J., Ye, S., Zeller, T., Cambien, F., Goodall, A. H., Marz, W., Blankenberg, S., Roberts, R., McPherson, R., Hopewell, J. C., Parish, S., Offer, A., Bowman, L., Sleight, P., Armitage, J., Peto, R., Collins, R., Chambers, J. C., Ahmed, N., Donnelly, P., Kooner, A. S., Scott, J., Sehmi, J., Zhang, W., Kooner, J., Sabater-Lleal, M., Mälarstig, A., Hellénius, M. L., Olsson, G., Rust, S., Assmann, G., Seedorf, U., Barlera, S., Tognoni, G., Franzosi, M. G., Linksted, P., Ongen, H., Kyriakou, T., Green, F., Farrall, M., Saleheen, D., Rasheed, A., Zaidi, M., Shah, N., Samuel, M., Mallick, N., Azhar, M., Zaman, K., Samad, A., Ishaq, M., Gardezi, A., Memon, F. U. R., Frossard, P., Danesh, J., Östenson, C. G., Lind, L., Cooper, C. C., Serrano-Ríos, M., Ferrannini, E., Forsen, T. J., Pattou, F., Langenberg, C., Hamsten, A. & Florez, J. C., Oct 1 2011, In: Diabetes. 60, 10, p. 2624-2634 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    289 Scopus citations

  • Genomic footprints of activated telomere maintenance mechanisms in cancer

    PCAWG Structural Variation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 733.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    70 Scopus citations

  • Gramene 2013: Comparative plant genomics resources

    Monaco, M. K., Stein, J., Naithani, S., Wei, S., Dharmawardhana, P., Kumari, S., Amarasinghe, V., Youens-Clark, K., Thomason, J., Preece, J., Pasternak, S., Olson, A., Jiao, Y., Lu, Z., Bolser, D., Kerhornou, A., Staines, D., Walts, B., Wu, G., D'Eustachio, P., & 6 othersHaw, R., Croft, D., Kersey, P. J., Stein, L., Jaiswal, P. & Ware, D., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D1193-D1199

    Research output: Contribution to journal › Article › peer-review

    Open Access
    149 Scopus citations

  • High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations

    PCAWG Transcriptome Working Group, PCAWG Structural Variation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 736.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    46 Scopus citations

  • Identification of a Therapeutic Strategy Targeting Amplified FGF19 in Liver Cancer by Oncogenomic Screening

    Sawey, E. T., Chanrion, M., Cai, C., Wu, G., Zhang, J., Zender, L., Zhao, A., Busuttil, R. W., Yee, H., Stein, L., French, D. M., Finn, R. S., Lowe, S. W. & Powers, S., Mar 8 2011, In: Cancer Cell. 19, 3, p. 347-358 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    351 Scopus citations

  • Illuminate the Functions of Dark Proteins Using the Reactome-IDG Web Portal

    Beavers, D., Brunson, T., Sanati, N., Matthews, L., Haw, R., Shorser, S., Sevilla, C., Viteri, G., Conley, P., Rothfels, K., Hermjakob, H., Stein, L., D'Eustachio, P. & Wu, G., Jul 2023, In: Current Protocols. 3, 7, e845.

    Research output: Contribution to journal › Article › peer-review

    1 Scopus citations

  • Integrative analysis of drug response and clinical outcome in acute myeloid leukemia

    Bottomly, D., Long, N., Schultz, A. R., Kurtz, S. E., Tognon, C. E., Johnson, K., Abel, M., Agarwal, A., Avaylon, S., Benton, E., Blucher, A., Borate, U., Braun, T. P., Brown, J., Bryant, J., Burke, R., Carlos, A., Chang, B. H., Cho, H. J., Christy, S., & 74 othersCoblentz, C., Cohen, A. M., d'Almeida, A., Cook, R., Danilov, A., Dao, K. H. T., Degnin, M., Dibb, J., Eide, C. A., English, I., Hagler, S., Harrelson, H., Henson, R., Ho, H., Joshi, S. K., Junio, B., Kaempf, A., Kosaka, Y., Laderas, T., Lawhead, M., Lee, H., Leonard, J. T., Lin, C., Lind, E. F., Liu, S. Q., Lo, P., Loriaux, M. M., Luty, S., Maxson, J. E., Macey, T., Martinez, J., Minnier, J., Monteblanco, A., Mori, M., Morrow, Q., Nelson, D., Ramsdill, J., Rofelty, A., Rogers, A., Romine, K. A., Ryabinin, P., Saultz, J. N., Sampson, D. A., Savage, S. L., Schuff, R., Searles, R., Smith, R. L., Spurgeon, S. E., Sweeney, T., Swords, R. T., Thapa, A., Thiel-Klare, K., Traer, E., Wagner, J., Wilmot, B., Wolf, J., Wu, G., Yates, A., Zhang, H., Cogle, C. R., Collins, R. H., Deininger, M. W., Hourigan, C. S., Jordan, C. T., Lin, T. L., Martinez, M. E., Pallapati, R. R., Pollyea, D. A., Pomicter, A. D., Watts, J. M., Weir, S. J., Druker, B. J., McWeeney, S. K. & Tyner, J. W., Aug 8 2022, In: Cancer Cell. 40, 8, p. 850-864.e9

    Research output: Contribution to journal › Article › peer-review

    Open Access
    76 Scopus citations

  • Integrative pathway enrichment analysis of multivariate omics data

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 735.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    96 Scopus citations

  • Leveraging biochemical reactions to unravel functional impacts of cancer somatic variants affecting protein interaction interfaces

    Raimondi, F., Burkhart, J. G., Betts, M. J., Russell, R. B. & Wu, G., 2021, In: F1000Research. 10, p. 1111 1 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Scopus citations

  • Leveraging biochemical reactions to unravel functional impacts of cancer somatic variants affecting protein interaction interfaces

    Raimondi, F., Wu, G., Burkhart, J. G., Betts, M. J. & Russell, R. B., 2022, In: F1000Research. 10, 1111.

    Research output: Contribution to journal › Article › peer-review

    Open Access

  • Manic fringe promotes a claudin-low breast cancer phenotype through notch-mediated PIK3CG induction

    Zhang, S., Chung, W. C., Wu, G., Egan, S. E., Miele, L. & Xu, K., May 15 2015, In: Cancer Research. 75, 10, p. 1936-1943 8 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations

  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    The MAGIC investigators & The GIANT consortium, Aug 7 2014, In: PLoS genetics. 10, 8, e1004517.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    167 Scopus citations

  • Natural product target network reveals potential for cancer combination therapies

    Chamberlin, S. R., Blucher, A., Wu, G., Shinto, L., Choonoo, G., Kulesz-Martin, M. & McWeeney, S., 2019, In: Frontiers in Pharmacology. 10, MAY, 557.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    42 Scopus citations

  • Network-based predictors of progression in head and neck squamous cell carcinoma

    Sanati, N., Iancu, O. D., Wu, G., Jacobs, J. E. & McWeeney, S. K., May 29 2018, In: Frontiers in Genetics. 9, MAY, 183.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    21 Scopus citations

  • Pan-cancer analysis of whole genomes

    The ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium, Feb 6 2020, In: Nature. 578, 7793, p. 82-93 12 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1568 Scopus citations

  • Pathway and network analysis of more than 2500 whole cancer genomes

    PCAWG Drivers and Functional Interpretation Working Group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 729.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    62 Scopus citations

  • Plant Reactome: A resource for plant pathways and comparative analysis

    Naithani, S., Preece, J., D'Eustachio, P., Gupta, P., Amarasinghe, V., Dharmawardhana, P. D., Wu, G., Fabregat, A., Elser, J. L., Weiser, J., Keays, M., Fuentes, A. M. P., Petryszak, R., Stein, L. D., Ware, D. & Jaiswal, P., Jan 1 2017, In: Nucleic acids research. 45, D1, p. D1029-D1039

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations

  • Reactome: A knowledgebase of biological pathways

    Joshi-Tope, G., Gillespie, M., Vastrik, I., D'Eustachio, P., Schmidt, E., de Bono, B., Jassal, B., Gopinath, G. R., Wu, G. R., Matthews, L., Lewis, S., Birney, E. & Stein, L., Jan 1 2005, In: Nucleic acids research. 33, DATABASE ISS., p. D428-D432

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1054 Scopus citations

  • Reactome: A knowledge base of biologic pathways and processes

    Vastrik, I., D'Eustachio, P., Schmidt, E., Joshi-Tope, G., Gopinath, G., Croft, D., de Bono, B., Gillespie, M., Jassal, B., Lewis, S., Matthews, L., Wu, G., Birney, E. & Stein, L., Mar 16 2007, In: Genome biology. 8, 3, R39.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    499 Scopus citations

  • Reactome: A database of reactions, pathways and biological processes

    Croft, D., O'Kelly, G., Wu, G., Haw, R., Gillespie, M., Matthews, L., Caudy, M., Garapati, P., Gopinath, G., Jassal, B., Jupe, S., Kalatskaya, I., MayMahajan, S., May, B., Ndegwa, N., Schmidt, E., Shamovsky, V., Yung, C., Birney, E., Hermjakob, H., & 2 othersD'Eustachio, P. & Stein, L., Jan 2011, In: Nucleic acids research. 39, SUPPL. 1, p. D691-D697

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1208 Scopus citations

  • Reactome and ORCID-fine-grained credit attribution for community curation

    Viteri, G., Matthews, L., Varusai, T., Gillespie, M., Milacic, M., Cook, J., Weiser, J., Shorser, S., Sidiropoulos, K., Fabregat, A., Haw, R., Wu, G., Stein, L., D'Eustachio, P. & Hermjakob, H., Jan 1 2019, In: Database : the journal of biological databases and curation. 2019

    Research output: Contribution to journal › Article › peer-review

    Open Access
    9 Scopus citations

  • ReactomeFIViz: A cytoscape app for pathway and network-based data analysis

    Wu, G., Dawson, E., Duong, A., Haw, R. & Stein, L., Sep 12 2014, In: F1000Research. 3, 4431.2.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    173 Scopus citations

  • Reactome from a WikiPathways Perspective

    Bohler, A., Wu, G., Kutmon, M., Pradhana, L. A., Coort, S. L., Hanspers, K., Haw, R., Pico, A. R. & Evelo, C. T., May 2016, In: PLoS computational biology. 12, 5, e1004941.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    30 Scopus citations

  • Reactome graph database: Efficient access to complex pathway data

    Fabregat, A., Korninger, F., Viteri, G., Sidiropoulos, K., Marin-Garcia, P., Ping, P., Wu, G., Stein, L., D’Eustachio, P. & Hermjakob, H., Jan 2018, In: PLoS computational biology. 14, 1, e1005968.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    170 Scopus citations

  • Reactome knowledgebase of human biological pathways and processes

    Matthews, L., Gopinath, G., Gillespie, M., Caudy, M., Croft, D., de Bono, B., Garapati, P., Hemish, J., Hermjakob, H., Jassal, B., Kanapin, A., Lewis, S., Mahajan, S., May, B., Schmidt, E., Vastrik, I., Wu, G., Birney, E., Stein, L. & D'eustachio, P., 2009, In: Nucleic acids research. 37, SUPPL. 1, p. D619-D622

    Research output: Contribution to journal › Article › peer-review

    Open Access
    691 Scopus citations

  • Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

    MC3 Working Group, PCAWG novel somatic mutation calling methods working group & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4748.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Scopus citations

  • Sex differences in oncogenic mutational processes

    PCAWG Tumour Subtypes and Clinical Translation & PCAWG Consortium, Dec 1 2020, In: Nature communications. 11, 1, 4330.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    54 Scopus citations

  • Systematic MicroRNA Analysis Identifies ATP6V0C as an Essential Host Factor for Human Cytomegalovirus Replication

    Pavelin, J., Reynolds, N., Chiweshe, S., Wu, G., Tiribassi, R. & Grey, F., 2013, In: PLoS pathogens. 9, 12, p. 1-13 13 p., e1003820.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    39 Scopus citations

  • The genome knowledgebase: A resource for biologists and bioinformaticists

    Joshi-Tope, G., Vastrik, I., Gopinath, G. R., Matthews, L., Schmidt, E., Gillespie, M., D'Eustachio, P., Jassal, B., Lewis, S., Wu, G., Birney, E. & Stein, L., 2003, In: Cold Spring Harbor symposia on quantitative biology. 68, p. 237-243 7 p.

    Research output: Contribution to journal › Article › peer-review

    45 Scopus citations

  • The landscape of viral associations in human cancers

    PCAWG Pathogens & PCAWG Consortium, Mar 1 2020, In: Nature genetics. 52, 3, p. 320-330 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    225 Scopus citations

  • The reactome pathway knowledgebase

    Fabregat, A., Sidiropoulos, K., Garapati, P., Gillespie, M., Hausmann, K., Haw, R., Jassal, B., Jupe, S., Korninger, F., McKay, S., Matthews, L., May, B., Milacic, M., Rothfels, K., Shamovsky, V., Webber, M., Weiser, J., Williams, M., Wu, G., Stein, L., & 2 othersHermjakob, H. & D'Eustachio, P., 2016, In: Nucleic acids research. 44, D1, p. D481-D487

    Research output: Contribution to journal › Article › peer-review

    Open Access
    982 Scopus citations

  • The reactome pathway knowledgebase

    Jassal, B., Matthews, L., Viteri, G., Gong, C., Lorente, P., Fabregat, A., Sidiropoulos, K., Cook, J., Gillespie, M., Haw, R., Loney, F., May, B., Milacic, M., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2020, In: Nucleic acids research. 48, D1, p. D498-D503

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1656 Scopus citations

  • The Reactome pathway knowledgebase

    Croft, D., Mundo, A. F., Haw, R., Milacic, M., Weiser, J., Wu, G., Caudy, M., Garapati, P., Gillespie, M., Kamdar, M. R., Jassal, B., Jupe, S., Matthews, L., May, B., Palatnik, S., Rothfels, K., Shamovsky, V., Song, H., Williams, M., Birney, E., & 3 othersHermjakob, H., Stein, L. & D'Eustachio, P., Jan 1 2014, In: Nucleic acids research. 42, D1, p. D472-D477

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1238 Scopus citations

  • The Reactome Pathway Knowledgebase

    Fabregat, A., Jupe, S., Matthews, L., Sidiropoulos, K., Gillespie, M., Garapati, P., Haw, R., Jassal, B., Korninger, F., May, B., Milacic, M., Roca, C. D., Rothfels, K., Sevilla, C., Shamovsky, V., Shorser, S., Varusai, T., Viteri, G., Weiser, J., Wu, G., & 3 othersStein, L., Hermjakob, H. & D'Eustachio, P., Jan 1 2018, In: Nucleic acids research. 46, D1, p. D649-D655

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1763 Scopus citations

  • The reactome pathway knowledgebase 2022

    Gillespie, M., Jassal, B., Stephan, R., Milacic, M., Rothfels, K., Senff-Ribeiro, A., Griss, J., Sevilla, C., Matthews, L., Gong, C., Deng, C., Varusai, T., Ragueneau, E., Haider, Y., May, B., Shamovsky, V., Weiser, J., Brunson, T., Sanati, N., Beckman, L., & 15 othersShao, X., Fabregat, A., Sidiropoulos, K., Murillo, J., Viteri, G., Cook, J., Shorser, S., Bader, G., Demir, E., Sander, C., Haw, R., Wu, G., Stein, L., Hermjakob, H. & D'Eustachio, P., Jan 7 2022, In: Nucleic acids research. 50, D1, p. D687-D692

    Research output: Contribution to journal › Article › peer-review

    Open Access
    727 Scopus citations