Knight Cancer Quantitative Oncology Program

Research output

Research output per year 1980 2016 2017 2018 2019 2020 2021 2022 2023 2024

• 594 Article
• 69 Review article
• 48 Comment/debate
• 27 Conference contribution
• 50 More
  • 20 Chapter
  • 12 Letter
  • 7 Conference article
  • 7 Editorial
  • 3 Short survey
  • 1 Paper

Research output per year

Research output per year

Search results

• 2024

  Dynamic Contrast-Enhanced (DCE) MRI

  Li, X., Huang, W. & Holmes, J. H., Feb 2024, In: Magnetic Resonance Imaging Clinics of North America. 32, 1, p. 47-61 15 p.

  Research output: Contribution to journal › Review article › peer-review
  1 Scopus citations

• Imaging of the hepatic arterial infusion pump: Primer for radiologists

  Bonde, A., Fung, A. W., Mayo, S. C., Li, P., Walker, B. S., Jaganathan, S., Mallak, N. & Korngold, E. K., Jan 2024, In: Clinical Imaging. 105, 110022.

  Research output: Contribution to journal › Review article › peer-review

  • Infusion Pumps 100%
  • Radiologists 70%
  • Liver 39%
  • Perfusion Imaging 11%
  • Cholangiocarcinoma 10%
• 2023

  Advances in Early Detection of Melanoma and the Future of At-Home Testing

  Garrison, Z. R., Hall, C. M., Fey, R. M., Clister, T., Khan, N., Nichols, R. & Kulkarni, R. P., Apr 2023, In: Life. 13, 4, 974.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • melanoma 100%
  • Melanoma 71%
  • artificial intelligence 41%
  • mortality 40%
  • testing 33%
  2 Scopus citations

• A framework for considering prior information in network-based approaches to omics data analysis

  Somers, J., Fenner, M., Kong, G., Thirumalaisamy, D., Yashar, W. M., Thapa, K., Kinali, M., Nikolova, O., Babur, Ö. & Demir, E., Nov 2023, In: Proteomics. 23, 21-22, 2200402.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Information Services 100%
  • Mechanics 93%
  • Data Analysis 61%
  • Information Systems 45%
  • Datasets 32%

• A Framework for Evaluating the Technical Performance of Multiparameter Quantitative Imaging Biomarkers (mp-QIBs)

  Obuchowski, N. A., Huang, E., deSouza, N. M., Raunig, D., Delfino, J., Buckler, A., Hatt, C., Wang, X., Moskowitz, C., Guimaraes, A., Giger, M., Hall, T. J., Kinahan, P. & Pennello, G., Feb 2023, In: Academic radiology. 30, 2, p. 147-158 12 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biomarkers 100%
  • Phenotype 92%
  • Medicine 56%
  9 Scopus citations

• Characteristics of genetic tags for correlative light and electron microscopy

  Beatty, K. E. & López, C. S., Oct 2023, In: Current Opinion in Chemical Biology. 76, 102369.

  Research output: Contribution to journal › Review article › peer-review

  • Optical Microscopy 100%
  • Electron Microscopy 97%
  • Microscopy 93%
  • Light 79%
  • Protein 46%
  1 Scopus citations

• Current and Future Applications of Fluorescence Guidance in Orthopaedic Surgery

  Streeter, S. S., Hebert, K. A., Bateman, L. M., Ray, G. S., Dean, R. E., Geffken, K. T., Resnick, C. T., Austin, D. C., Bell, J. E., Sparks, M. B., Gibbs, S. L., Samkoe, K. S., Gitajn, I. L., Elliott, J. T. & Henderson, E. R., Feb 2023, In: Molecular Imaging and Biology. 25, 1, p. 46-57 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Orthopedic Procedures 100%
  • Fluorescence 75%
  • Orthopedics 33%
  • Patient Care 14%
  • Perfusion 13%
  9 Scopus citations

• Defining clonal hematopoiesis of indeterminate potential: evolutionary dynamics and detection under aging and inflammation

  Goldman, E. A., Spellman, P. T. & Agarwal, A., Apr 2023, In: Cold Spring Harbor Molecular Case Studies. 9, 2, a006251.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Hematopoiesis 100%
  • Inflammation 54%
  • Hematologic Neoplasms 14%
  • Hematopoietic Stem Cells 13%
  • Epigenome 8%
  2 Scopus citations

• Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing

  Kashani-Sabet, M., Leachman, S. A., Stein, J. A., Arbiser, J. L., Berry, E. G., Celebi, J. T., Curiel-Lewandrowski, C., Ferris, L. K., Grant-Kels, J. M., Grossman, D., Kulkarni, R. P., Marchetti, M. A., Nelson, K. C., Polsky, D., Seiverling, E. V., Swetter, S. M., Tsao, H., Verdieck-Devlaeminck, A., Wei, M. L., Bar, A., & 23 othersBartlett, E. K., Bolognia, J. L., Bowles, T. L., Cha, K. B., Chu, E. Y., Hartman, R. I., Hawryluk, E. B., Jampel, R. M., Karapetyan, L., Kheterpal, M., Lawson, D. H., Leming, P. D., Liebman, T. N., Ming, M. E., Sahni, D., Savory, S. A., Shaikh, S. S., Sober, A. J., Sondak, V. K., Spaccarelli, N., Usatine, R. P., Venna, S. & Kirkwood, J. M., May 17 2023, In: JAMA Dermatology. 159, 5, p. 545-553 9 p.

  Research output: Contribution to journal › Review article › peer-review

  • Transcriptome 100%
  • Melanoma 90%
  • Skin 59%
  • Dielectric Spectroscopy 20%
  • Dermoscopy 18%
  6 Scopus citations

• Immunomodulatory roles of PARPs: Shaping the tumor microenvironment, one ADP-ribose at a time

  Brooks, D. M., Anand, S. & Cohen, M. S., Dec 2023, In: Current Opinion in Chemical Biology. 77, 102402.

  Research output: Contribution to journal › Review article › peer-review

  • Adenosine Diphosphate Ribose 100%
  • Tumor Microenvironment 71%
  • Mutation 57%
  • Modification 38%
  • Drug 36%

• Improving precision surgery: A review of current intraoperative nerve tissue fluorescence imaging

  Wang, L. G. & Gibbs, S. L., Oct 2023, In: Current Opinion in Chemical Biology. 76, 102361.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Pipeline 100%
  • Nerve Tissue 98%
  • Contrast Medium 96%
  • Optical Imaging 94%
  • Safety 73%
  4 Scopus citations

• Intraoperative molecular imaging: 3rd biennial clinical trials update

  Bou-Samra, P., Muhammad, N., Chang, A., Karsalia, R., Azari, F., Kennedy, G., Stummer, W., Tanyi, J., Martin, L., Vahrmeijer, A., Smith, B., Rosenthal, E., Wagner, P., Rice, D., Lee, A., Abdelhafeez, A., Malek, M. M., Kohanbash, G., Barry Edwards, W., Henderson, E., & 13 othersSkjøth-Rasmussen, J., Orosco, R., Gibbs, S., Farnam, R. W., Shankar, L., Sumer, B., Kumar, A. T. N., Marcu, L., Li, L., Greuv, V., Delikatny, E. J., Lee, J. Y. K. & Singhal, S., May 1 2023, In: Journal of biomedical optics. 28, 5, 050901.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Molecular imaging 100%
  • Molecular Imaging 67%
  • Dyes 64%
  • dyes 49%
  • Coloring Agents 47%
  9 Scopus citations

• Monitoring and Surveillance of Patients with Gastroenteropancreatic Neuroendocrine Tumors Undergoing Radioligand Therapy

  Halfdanarson, T. R., Mallak, N., Paulson, S., Chandrasekharan, C., Natwa, M., Kendi, A. T. & Kennecke, H. F., Oct 2023, In: Cancers. 15, 19, 4836.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Gastro-enteropancreatic neuroendocrine tumor 100%
  • Physiologic Monitoring 68%
  • Somatostatin Receptors 41%
  • Patient Care Team 19%
  • Nuclear Medicine 18%

• Multiparametric Data-driven Imaging Markers: Guidelines for Development, Application and Reporting of Model Outputs in Radiomics

  Wang, X., Pennello, G., deSouza, N. M., Huang, E. P., Buckler, A. J., Barnhart, H. X., Delfino, J. G., Raunig, D. L., Wang, L., Guimaraes, A. R., Hall, T. J. & Obuchowski, N. A., Feb 2023, In: Academic radiology. 30, 2, p. 215-229 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Machine Learning 100%
  • Data Analysis 99%
  • Guidelines 85%
  • Lung Neoplasms 35%
  • Biomarkers 28%
  8 Scopus citations

• Multiparametric Quantitative Imaging Biomarker as a Multivariate Descriptor of Health: A Roadmap

  Raunig, D. L., Pennello, G. A., Delfino, J. G., Buckler, A. J., Hall, T. J., Guimaraes, A. R., Wang, X., Huang, E. P., Barnhart, H. X., deSouza, N. & Obuchowski, N., Feb 2023, In: Academic radiology. 30, 2, p. 159-182 24 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Biomarkers 100%
  • Health 74%
  • Datasets 10%
  • Alzheimer Disease 9%
  6 Scopus citations

• Multiparametric Quantitative Imaging Biomarkers for Phenotype Classification: A Framework for Development and Validation

  Delfino, J. G., Pennello, G. A., Barnhart, H. X., Buckler, A. J., Wang, X., Huang, E. P., Raunig, D. L., Guimaraes, A. R., Hall, T. J., deSouza, N. M. & Obuchowski, N., Feb 2023, In: Academic radiology. 30, 2, p. 183-195 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biomarkers 100%
  • Phenotype 92%
  • Manuscripts 44%
  • Validation Studies 42%
  • Atherosclerotic Plaques 40%
  4 Scopus citations

• Multiparametric Quantitative Imaging in Risk Prediction: Recommendations for Data Acquisition, Technical Performance Assessment, and Model Development and Validation

  Huang, E. P., Pennello, G., deSouza, N. M., Wang, X., Buckler, A. J., Kinahan, P. E., Barnhart, H. X., Delfino, J. G., Hall, T. J., Raunig, D. L., Guimaraes, A. R. & Obuchowski, N. A., Feb 2023, In: Academic radiology. 30, 2, p. 196-214 19 p.

  Research output: Contribution to journal › Review article › peer-review

  • Biomarkers 100%
  • Evaluation Studies 27%
  • Recurrence 17%
  5 Scopus citations

• Nanotechnology Applications in Breast Cancer Immunotherapy

  Wang, R., Kumar, P., Reda, M., Wallstrum, A. G., Crumrine, N. A., Ngamcherdtrakul, W. & Yantasee, W., 2023, (Accepted/In press) In: Small.

  Research output: Contribution to journal › Review article › peer-review

  • Nanotechnology 100%
  • T-cells 93%
  • Tumors 85%
  • Immunotherapy 74%
  • Breast Neoplasms 53%
  3 Scopus citations

• Radiotherapy reimagined: Integrating nanomedicines into radiotherapy clinical trials

  DuRoss, A. N., Phan, J., Lazar, A. J., Walker, J. M., Guimaraes, A. R., Baas, C., Krishnan, S., Thomas, C. R., Sun, C. & Bagley, A. F., May 1 2023, In: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology. 15, 3, e1867.

  Research output: Contribution to journal › Review article › peer-review

  • Medical nanotechnology 100%
  • Nanomedicine 74%
  • Radiotherapy 71%
  • Nanoparticles 57%
  • Tumors 39%
  4 Scopus citations

• State-of-the-art computational methods to predict protein–protein interactions with high accuracy and coverage

  Kewalramani, N., Emili, A. & Crovella, M., Nov 2023, In: Proteomics. 23, 21-22, 2200292.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Deep Learning 100%
  • Information Storage and Retrieval 99%
  • Protein Structure 88%
  • Protein 75%
  • Proteins 66%

• Using single molecule imaging to explore intracellular heterogeneity

  Galbraith, J. A. & Galbraith, C. G., Oct 2023, In: International Journal of Biochemistry and Cell Biology. 163, 106455.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Single Molecule Imaging 100%
  • Amyloid Fibril 86%
  • Heterogeneity 67%
  • Phase Separation 63%
  • Environment 41%
• 2022

  Chemical genetic methodologies for identifying protein substrates of PARPs

  Rodriguez, K. M. & Cohen, M. S., May 2022, In: Trends in Biochemical Sciences. 47, 5, p. 390-402 13 p.

  Research output: Contribution to journal › Review article › peer-review

  • Poly(ADP-ribose) Polymerases 100%
  • Protein 34%
  • ADP-Ribosylation 32%
  • Proteins 30%
  • Mammalian Cell 28%
  8 Scopus citations

• Circulating biomarkers of response to immunotherapy and immune-related adverse events

  Garrison, Z., Hornick, N., Cheng, J. & Kulkarni, R. P., 2022, In: Expert Review of Molecular Diagnostics. 22, 9, p. 855-865 11 p.

  Research output: Contribution to journal › Review article › peer-review

  • Immunotherapy 100%
  • Biomarkers 73%
  • Prospective Studies 14%
  • Therapeutics 7%
  • Neoplasms 7%
  2 Scopus citations

• Inverting the model of genomics data sharing with the NHGRI Genomic Data Science Analysis, Visualization, and Informatics Lab-space

  AnVIL Team, Jan 12 2022, In: Cell Genomics. 2, 1, 100085.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • National Human Genome Research Institute (U.S.) 100%
  • Data Science 78%
  • Informatics 71%
  • Ecosystem 67%
  • Information Dissemination 66%
  48 Scopus citations

• Mechanisms of dermatological toxicities to immune checkpoint inhibitor cancer therapies

  Seervai, R. N. H., Sinha, A. & Kulkarni, R. P., Nov 2022, In: Clinical and Experimental Dermatology. 47, 11, p. 1928-1942 15 p.

  Research output: Contribution to journal › Review article › peer-review

  • Skin 100%
  • Neoplasms 58%
  • Survival 50%
  • CTLA-4 Antigen 42%
  • Melanocytes 34%
  5 Scopus citations

• Molecular and Anatomic Imaging of Neuroendocrine Tumors

  Szidonya, L., Park, E. A., Kwak, J. J. & Mallak, N., Oct 2022, In: Surgical Oncology Clinics of North America. 31, 4, p. 649-671 23 p.

  Research output: Contribution to journal › Review article › peer-review

• Ras Multimers on the Membrane: Many Ways for a Heart-to-Heart Conversation

  Ozdemir, E. S., Koester, A. M. & Nan, X., Feb 2022, In: Genes. 13, 2, 219.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Thinking 100%
  • Membranes 60%
  • In Vitro Techniques 44%
  5 Scopus citations

• Therapy Resistant Gastroenteropancreatic Neuroendocrine Tumors

  McClellan, K., Chen, E. Y., Kardosh, A., Lopez, C. D., Del Rivero, J., Mallak, N., Rocha, F. G., Koethe, Y., Pommier, R., Mittra, E. & Pegna, G. J., Oct 2022, In: Cancers. 14, 19, 4769.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Gastro-enteropancreatic neuroendocrine tumor 100%
  • Lutetium-177 38%
  • Sunitinib 27%
  • Neuroendocrine Cells 27%
  • Everolimus 27%
  5 Scopus citations
• 2021

  Dielectrophoresis: Developments and applications from 2010 to 2020

  Sarno, B., Heineck, D., Heller, M. J. & Ibsen, S. D., Mar 2021, In: ELECTROPHORESIS. 42, 5, p. 539-564 26 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Dielectrophoresis 100%
  • Patents 60%
  • Technology 49%
  • Microtechnology 37%
  • Technology Transfer 36%
  46 Scopus citations

• Interpretation of cancer mutations using a multiscale map of protein systems

  Zheng, F., Kelly, M. R., Ramms, D. J., Heintschel, M. L., Tao, K., Tutuncuoglu, B., Lee, J. J., Ono, K., Foussard, H., Chen, M., Herrington, K. A., Silva, E., Liu, S. N., Chen, J., Churas, C., Wilson, N., Kratz, A., Pillich, R. T., Patel, D. N., Park, J., & 12 othersKuenzi, B., Yu, M. K., Licon, K., Pratt, D., Kreisberg, J. F., Kim, M., Swaney, D. L., Nan, X., Fraley, S. I., Gutkind, J. S., Krogan, N. J. & Ideker, T., Oct 1 2021, In: Science. 374, 6563, abf3067.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Mutation 100%
  • Proteins 65%
  • Neoplasms 57%
  • Multiprotein Complexes 39%
  • Actomyosin 39%
  19 Scopus citations

• Intraoperative molecular imaging clinical trials: A review of 2020 conference proceedings

  Azari, F., Kennedy, G., Bernstein, E., Hadjipanayis, C., Vahrmeijer, A. L., Smith, B. L., Rosenthal, E., Sumer, B., Tian, J., Henderson, E. R., Lee, A., Nguyen, Q., Gibbs, S. L., Pogue, B. W., Orringer, D. A., Charalampaki, P., Martin, L. W., Tanyi, J. L., Kenneth Lee, M., Lee, J. Y. K., & 1 othersSinghal, S., May 1 2021, In: Journal of biomedical optics. 26, 5, 050901.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Molecular imaging 100%
  • Art 68%
  • Molecular Imaging 67%
  • Contrast Medium 63%
  • Congresses 56%
  29 Scopus citations

• Non-specific orbital inflammation: Current understanding and unmet needs

  Lee, M. J., Planck, S. R., Choi, D., Harrington, C. A., Wilson, D. J., Dailey, R. A., Ng, J. D., Steele, E. A., Hamilton, B. E., Khwarg, S. I. & Rosenbaum, J. T., Mar 2021, In: Progress in Retinal and Eye Research. 81, 100885.

  Research output: Contribution to journal › Review article › peer-review

  • Inflammation 100%
  • Exophthalmos 29%
  • Diplopia 28%
  • Orbit 26%
  • Gene Expression Profiling 25%
  20 Scopus citations

• Prognostic and therapeutic role of tumor-infiltrating lymphocyte subtypes in breast cancer

  Nelson, M. A., Ngamcherdtrakul, W., Luoh, S. W. & Yantasee, W., Jun 2021, In: Cancer and Metastasis Reviews. 40, 2, p. 519-536 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Tumor-Infiltrating Lymphocytes 100%
  • Breast Neoplasms 50%
  • Natural Killer Cells 43%
  • T-Lymphocytes 38%
  • Antigen-Presenting Cells 33%
  57 Scopus citations

• Stimuli-responsive mesoporous silica nanoparticles: A custom-tailored next generation approach in cargo delivery

  Salve, R., Kumar, P., Ngamcherdtrakul, W., Gajbhiye, V. & Yantasee, W., May 2021, In: Materials Science and Engineering C. 124, 112084.

  Research output: Contribution to journal › Review article › peer-review

  • Silica nanoparticles 100%
  • cargo 86%
  • drugs 66%
  • delivery 63%
  • stimuli 61%
  27 Scopus citations

• The potential of tear proteomics for diagnosis and management of orbital inflammatory disorders including Graves’ ophthalmopathy

  Khazaei, H., Khazaei, D., Verma, R., Ng, J., Wilmarth, P., David, L. L. & Rosenbaum, J., Dec 2021, In: Experimental Eye Research. 213, 108813.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Graves Ophthalmopathy 100%
  • Tears 70%
  • Proteomics 67%
  • tear proteins 60%
  • Orbital Diseases 56%
  4 Scopus citations
• 2020

  Augmenting the therapeutic window of radiotherapy: A perspective on molecularly targeted therapies and nanomaterials

  Reda, M., Bagley, A. F., Zaidan, H. Y. & Yantasee, W., Sep 2020, In: Radiotherapy and Oncology. 150, p. 225-235 11 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Nanostructures 100%
  • Radiotherapy 59%
  • Nanoparticles 33%
  • Ionizing Radiation 19%
  • Neoplasms 18%
  10 Scopus citations

• Fluorescent probes for investigating peptidoglycan biosynthesis in mycobacteria

  Beatty, K. E., Aug 2020, In: Current Opinion in Chemical Biology. 57, p. 50-57 8 p.

  Research output: Contribution to journal › Review article › peer-review

  • Peptidoglycan 100%
  • Mycobacterium 84%
  • Fluorescent Dyes 82%
  • Fluorescent Probe 72%
  • Biosynthesis 65%
  9 Scopus citations

• How Machine Learning Will Transform Biomedicine

  Goecks, J., Jalili, V., Heiser, L. M. & Gray, J. W., Apr 2 2020, In: Cell. 181, 1, p. 92-101 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Machine Learning 100%
  • Application 27%
  • Health 17%
  • Individuality 17%
  • Ocular Vision 14%
  266 Scopus citations

• Interplay between compartmentalized NAD⁺ synthesis and consumption: A focus on the PARP family

  Cohen, M. S., Mar 1 2020, In: Genes and Development. 34, 5, p. 254-262 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Poly(ADP-ribose) Polymerases 100%
  • NAD 86%
  • Enzymes 18%
  • Oxidation-Reduction 16%
  • Adenosine Diphosphate Ribose 12%
  63 Scopus citations

• Mechanisms governing PARP expression, localization, and activity in cells

  Sanderson, D. J. & Cohen, M. S., Dec 2020, In: Critical Reviews in Biochemistry and Molecular Biology. 55, 6, p. 541-554 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Poly(ADPribose) 100%
  • Poly(ADP-ribose) Polymerases 87%
  • Adenosine Diphosphate Ribose 53%
  • Poly ADP-ribosylation 42%
  • Poly ADP Ribosylation 36%
  18 Scopus citations

• SBML Level 3: an extensible format for the exchange and reuse of biological models

  Keating, S. M., Waltemath, D., König, M., Zhang, F., Dräger, A., Chaouiya, C., Bergmann, F. T., Finney, A., Gillespie, C. S., Helikar, T., Hoops, S., Malik-Sheriff, R. S., Moodie, S. L., Moraru, I. I., Myers, C. J., Naldi, A., Olivier, B. G., Sahle, S., Schaff, J. C., Smith, L. P., & 121 othersSwat, M. J., Thieffry, D., Watanabe, L., Wilkinson, D. J., Blinov, M. L., Begley, K., Faeder, J. R., Gómez, H. F., Hamm, T. M., Inagaki, Y., Liebermeister, W., Lister, A. L., Lucio, D., Mjolsness, E., Proctor, C. J., Raman, K., Rodriguez, N., Shaffer, C. A., Shapiro, B. E., Stelling, J., Swainston, N., Tanimura, N., Wagner, J., Meier-Schellersheim, M., Sauro, H. M., Palsson, B., Bolouri, H., Kitano, H., Funahashi, A., Hermjakob, H., Doyle, J. C., Hucka, M., Adams, R. R., Allen, N. A., Angermann, B. R., Antoniotti, M., Bader, G. D., Červený, J., Courtot, M., Cox, C. D., Dalle Pezze, P., Demir, E., Denney, W. S., Dharuri, H., Dorier, J., Drasdo, D., Ebrahim, A., Eichner, J., Elf, J., Endler, L., Evelo, C. T., Flamm, C., Fleming, R. M. T., Fröhlich, M., Glont, M., Gonçalves, E., Golebiewski, M., Grabski, H., Gutteridge, A., Hachmeister, D., Harris, L. A., Heavner, B. D., Henkel, R., Hlavacek, W. S., Hu, B., Hyduke, D. R., de Jong, H., Juty, N., Karp, P. D., Karr, J. R., Kell, D. B., Keller, R., Kiselev, I., Klamt, S., Klipp, E., Knüpfer, C., Kolpakov, F., Krause, F., Kutmon, M., Laibe, C., Lawless, C., Li, L., Loew, L. M., Machne, R., Matsuoka, Y., Mendes, P., Mi, H., Mittag, F., Monteiro, P. T., Natarajan, K. N., Nielsen, P. M. F., Nguyen, T., Palmisano, A., Pettit, J. B., Pfau, T., Phair, R. D., Radivoyevitch, T., Rohwer, J. M., Ruebenacker, O. A., Saez-Rodriguez, J., Scharm, M., Schmidt, H., Schreiber, F., Schubert, M., Schulte, R., Sealfon, S. C., Smallbone, K., Soliman, S., Stefan, M. I., Sullivan, D. P., Takahashi, K., Teusink, B., Tolnay, D., Vazirabad, I., von Kamp, A., Wittig, U., Wrzodek, C., Wrzodek, F., Xenarios, I., Zhukova, A. & Zucker, J., Aug 1 2020, In: Molecular Systems Biology. 16, 8, e9110.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Reuse 100%
  • Biological Models 99%
  • biological models 98%
  • Markup languages 96%
  • Systems Biology 96%
  136 Scopus citations
• 2019

  Better living through your gut microbes

  Kulkarni, R. P., Aug 14 2019, In: Science translational medicine. 11, 505, eaay7700.

  Research output: Contribution to journal › Review article › peer-review

  • Dysbiosis 100%
  • Bile Acids and Salts 82%
  • Longevity 71%
  • Health 38%

• Circulating biomarkers predictive of tumor response to cancer immunotherapy

  Lee, E. Y. & Kulkarni, R. P., Oct 3 2019, In: Expert Review of Molecular Diagnostics. 19, 10, p. 895-904 10 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Tumor Biomarkers 100%
  • Immunotherapy 90%
  • Biomarkers 41%
  • Neoplasms 33%
  • Precision Medicine 27%
  26 Scopus citations

• Coaxing cancer control by modulating COX-2

  Kulkarni, R. P., 2019, In: Science translational medicine. 11, 497, eaax9566.

  Research output: Contribution to journal › Review article › peer-review

  • Celecoxib 100%
  • Cyclooxygenase 2 Inhibitors 93%
  • Immunotherapy 69%
  • Adenocarcinoma 61%
  • Neoplasms 25%
  1 Scopus citations

• Coevolution of Genome Architecture and Social Behavior

  Rubenstein, D. R., Ågren, J. A., Carbone, L., Elde, N. C., Hoekstra, H. E., Kapheim, K. M., Keller, L., Moreau, C. S., Toth, A. L., Yeaman, S. & Hofmann, H. A., Sep 2019, In: Trends in Ecology and Evolution. 34, 9, p. 844-855 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • social behavior 100%
  • coevolution 94%
  • genome 71%
  • mating behavior 21%
  • molecular biology 15%
  34 Scopus citations

• Neuroinflammation in addiction: A review of neuroimaging studies and potential immunotherapies

  Kohno, M., Link, J., Dennis, L. E., McCready, H., Huckans, M., Hoffman, W. F. & Loftis, J. M., Apr 2019, In: Pharmacology Biochemistry and Behavior. 179, p. 34-42 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Neuroimaging 100%
  • ibudilast 99%
  • Immunotherapy 97%
  • Ibudilast 77%
  • Pioglitazone 69%
  96 Scopus citations

• Probiotics leap from gut to blood

  Kulkarni, R. P., Dec 4 2019, In: Science translational medicine. 11, 521, eaaz9763.

  Research output: Contribution to journal › Review article › peer-review

  • Probiotics 100%
  • Bacteremia 47%
  • Critical Illness 43%
  • Anti-Bacterial Agents 30%
  4 Scopus citations

• Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials

  Shukla-Dave, A., Obuchowski, N. A., Chenevert, T. L., Jambawalikar, S., Schwartz, L. H., Malyarenko, D., Huang, W., Noworolski, S. M., Young, R. J., Shiroishi, M. S., Kim, H., Coolens, C., Laue, H., Chung, C., Rosen, M., Boss, M. & Jackson, E. F., Jun 2019, In: Journal of Magnetic Resonance Imaging. 49, 7, p. e101-e121

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Multicenter Studies 100%
  • Biomarkers 74%
  • National Cancer Institute (U.S.) 14%
  • North America 13%
  • Permeability 10%
  235 Scopus citations

• siRNA therapeutics for breast cancer: recent efforts in targeting metastasis, drug resistance, and immune evasion

  Ngamcherdtrakul, W. & Yantasee, W., Dec 2019, In: Translational Research. 214, p. 105-120 16 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Small Interfering RNA 100%
  • Immune Evasion 91%
  • Drug Resistance 66%
  • cancer 65%
  • drug 48%
  48 Scopus citations

• Systems biology approaches to measure and model phenotypic heterogeneity in cancer

  Meyer, A. S. & Heiser, L. M., Oct 2019, In: Current Opinion in Systems Biology. 17, p. 35-40 6 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Systems Biology 100%
  • Cancer 78%
  • Heterogeneity 70%
  • Adaptive systems 41%
  • Cell 37%
  12 Scopus citations