Research output per year
Research output per year
- 1 - 50 out of 1,273 results
Search results
-
2024
A Nonheme Iron(III) Superoxide Complex Leads to Sulfur Oxygenation
Yadav, S., Yadav, V., Siegler, M. A., Moënne-Loccoz, P., Jameson, G. N. L. & Goldberg, D. P., Mar 27 2024, In: Journal of the American Chemical Society. 146, 12, p. 7915-7921 7 p.Research output: Contribution to journal › Article › peer-review
-
A rapid, tag-free way to purify functional GPCRs
Shumate, A. D. & Farrens, D. L., Jan 2024, In: Journal of Biological Chemistry. 300, 1, 105558.Research output: Contribution to journal › Article › peer-review
Open Access -
Chenodeoxycholic acid (CDCA) treatment during pregnancy in women with cerebrotendinous xanthomatosis (CTX): Lessons learned from 19 pregnancies
Zaccai, T. C. F., Hassin-Baer, S., Kfir, N. C., Duell, P. B., Neerhof, M., Sloma, R., Roitman, M., Kisanuki, Y. Y., Verrips, A. & DeBarber, A. E., May 2024, In: Genetics in Medicine. 26, 5, 101086.Research output: Contribution to journal › Article › peer-review
Open Access -
Effect of PCSK9 inhibition on plasma levels of small dense low density lipoprotein-cholesterol and 7-ketocholesterol
Mahmood, T., Miles, J. R., Minnier, J., Tavori, H., DeBarber, A. E., Fazio, S. & Shapiro, M. D., Jan 1 2024, In: Journal of clinical lipidology. 18, 1, p. e50-e58Research output: Contribution to journal › Article › peer-review
-
Profiling the proximal proteome of the activated μ-opioid receptor
Polacco, B. J., Lobingier, B. T., Blythe, E. E., Abreu, N., Khare, P., Howard, M. K., Gonzalez-Hernandez, A. J., Xu, J., Li, Q., Novy, B., Naing, Z. Z. C., Shoichet, B. K., Coyote-Maestas, W., Levitz, J., Krogan, N. J., Von Zastrow, M. & Hüttenhain, R., 2024, (Accepted/In press) In: Nature Chemical Biology.Research output: Contribution to journal › Article › peer-review
-
Split Retina as an Improved Flatmount Preparation for Studying Inner Nuclear Layer Neurons in Vertebrate Retina
Hecht, R. M., Shi, Q., Garrett, T. R., Sivyer, B. & Morgans, C., 2024, In: Journal of Visualized Experiments. 2024, 203, e65757.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure of an open KATP channel reveals tandem PIP2 binding sites mediating the Kir6.2 and SUR1 regulatory interface
Driggers, C. M., Kuo, Y. Y., Zhu, P., ElSheikh, A. & Shyng, S. L., Dec 2024, In: Nature communications. 15, 1, 2502.Research output: Contribution to journal › Article › peer-review
Open Access -
The α-crystallin Chaperones Undergo a Quasi-ordered Co-aggregation Process in Response to Saturating Client Interaction
Miller, A. P., O'Neill, S. E., Lampi, K. J. & Reichow, S. L., Apr 15 2024, In: Journal of molecular biology. 436, 8, 168499.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2023
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors
Iyer, S. R., Nusser, K., Jones, K., Shinde, P., Keddy, C., Beach, C. Z., Aguero, E., Force, J., Shinde, U. & Davare, M. A., Oct 11 2023, In: EMBO Molecular Medicine. 15, 10, e17367.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Experimental design considerations for studies of human tear proteins
Harkness, B. M., Hegarty, D. M., Saugstad, J. A., Behrens, H., Betz, J., David, L. L., Lapidus, J. A., Chen, S., Stutzman, R., Chamberlain, W., Perez-Blanco, M., Galor, A. & Aicher, S. A., Apr 2023, In: Ocular Surface. 28, p. 58-78 21 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Flipping the GPCR Switch: Structure-Based Development of Selective Cannabinoid Receptor 2 Inverse Agonists
Kosar, M., Sarott, R. C., Sykes, D. A., Viray, A. E. G., Vitale, R. M., Tomašević, N., Li, X., Ganzoni, R. L. Z., Kicin, B., Reichert, L., Patej, K. J., Gómez-Bouzó, U., Guba, W., McCormick, P. J., Hua, T., Gruber, C. W., Veprintsev, D. B., Frank, J. A., Grether, U. & Carreira, E. M., 2023, (Accepted/In press) In: ACS Central Science.Research output: Contribution to journal › Article › peer-review
Open Access -
Hydrogen atom abstraction by a high-spin [FeIII=S] complex
Valdez-Moreira, J. A., Wannipurage, D. C., Pink, M., Carta, V., Moënne-Loccoz, P., Telser, J. & Smith, J. M., Sep 14 2023, In: Chem. 9, 9, p. 2601-2609 9 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Impact of α-crystallin protein loss on zebrafish lens development
Posner, M., Murray, K. L., Andrew, B., Brdicka, S., Roberts, A., Franklin, K., Hussen, A., Kaye, T., Kepp, E., McDonald, M. S., Snodgrass, T., Zientek, K. & David, L. L., Feb 2023, In: Experimental Eye Research. 227, 109358.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Ligand-directed labeling of opioid receptors for covalent attachment of fluorophores or small-molecule probes
Adoff, H., Halls, V. S., Holland, E., Lobingier, B. & Arttamangkul, S., Jun 16 2023, In: STAR Protocols. 4, 2, 102231.Research output: Contribution to journal › Article › peer-review
Open Access -
Loss of chondroitin sulfate proteoglycan sulfation allows delayed sympathetic reinnervation after cardiac ischemia–reperfusion
Blake, M. R., Parrish, D. C., Staffenson, M. A., Johnson, M. A., Woodward, W. R. & Habecker, B. A., May 2023, In: Physiological reports. 11, 10, e15702.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Maternal Administration of the CNS-Selective Sobetirome Prodrug Sob-AM2 Exerts Thyromimetic Effects in Murine MCT8-Deficient Fetuses
Valcárcel-Hernández, V., Guillén-Yunta, M., Scanlan, T. S., Bárez-López, S. & Guadaño-Ferraz, A., May 1 2023, In: Thyroid. 33, 5, p. 632-640 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Neuronal ER-plasma membrane junctions couple excitation to Ca2+-activated PKA signaling
Vierra, N. C., Ribeiro-Silva, L., Kirmiz, M., van der List, D., Bhandari, P., Mack, O. A., Carroll, J., Le Monnier, E., Aicher, S. A., Shigemoto, R. & Trimmer, J. S., Dec 2023, In: Nature communications. 14, 1, 5231.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Novel Genetically Encoded Peptide Tags for Correlative Imaging: Lessons Learned
López, C. S., Devlin, K., Stempinski, E. S. & Beatty, K. E., Jul 22 2023, In: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 29, 1, p. 2099 1 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Optimization of Orally Bioavailable Antileishmanial 2,4,5-Trisubstituted Benzamides
Kim, H. S., Ortiz, D., Kadayat, T. M., Fargo, C. M., Hammill, J. T., Chen, Y., Rice, A. L., Begley, K. L., Shoeran, G., Pistel, W., Yates, P. A., Sanchez, M. A., Landfear, S. M. & Guy, R. K., Jun 8 2023, In: Journal of Medicinal Chemistry. 66, 11, p. 7374-7386 13 p.Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Orthogonal Versatile Interacting Peptide Tags for Imaging Cellular Proteins
Suyama, A., Devlin, K. L., Macias-Contreras, M., Doh, J. K., Shinde, U. & Beatty, K. E., Jun 6 2023, In: Biochemistry. 62, 11, p. 1735-1743 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Oxygen versus Sulfur Coordination in Cobalt Superoxo Complexes: Spectroscopic Properties, O2 Binding, and H-Atom Abstraction Reactivity
Gordon, J. B., Albert, T., Yadav, S., Thomas, J., Siegler, M. A., Moënne-Loccoz, P. & Goldberg, D. P., Jan 9 2023, In: Inorganic Chemistry. 62, 1, p. 392-400 9 p.Research output: Contribution to journal › Article › peer-review
-
Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells
Kosar, M., Sykes, D. A., Viray, A. E. G., Vitale, R. M., Sarott, R. C., Ganzoni, R. L., Onion, D., Tobias, J. M., Leippe, P., Ullmer, C., Zirwes, E. A., Guba, W., Grether, U., Frank, J. A., Veprintsev, D. B. & Carreira, E. M., Jul 19 2023, In: Journal of the American Chemical Society. 145, 28, p. 15094-15108 15 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Probing Ion Configurations in the KcsA Selectivity Filter with Single-Isotope Labels and 2D IR Spectroscopy
Ryan, M. J., Gao, L., Valiyaveetil, F. I., Zanni, M. T. & Kananenka, A. A., Aug 23 2023, In: Journal of the American Chemical Society. 145, 33, p. 18529-18537 9 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Promyelinating drugs promote functional recovery in an autism spectrum disorder mouse model of Pitt-Hopkins syndrome
Bohlen, J. F., Cleary, C. M., Das, D., Sripathy, S. R., Sadowski, N., Shim, G., Kenney, R. F., Buchler, I. P., Banerji, T., Scanlan, T. S., Mulkey, D. K. & Maher, B. J., Aug 1 2023, In: Brain. 146, 8, p. 3331-3346 16 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Proteomic profiling of retina and retinal pigment epithelium combined embryonic tissue to facilitate ocular disease gene discovery
Aryal, S., Anand, D., Huang, H., Reddy, A. P., Wilmarth, P. A., David, L. L. & Lachke, S. A., Jul 2023, In: Human genetics. 142, 7, p. 927-947 21 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Reductive Coupling of Nitric Oxide by Cu(I): Stepwise Formation of Mono- and Dinitrosyl Species En Route to a Cupric Hyponitrite Intermediate
Bhadra, M., Albert, T., Franke, A., Josef, V., Ivanović-Burmazović, I., Swart, M., Moënne-Loccoz, P. & Karlin, K. D., Feb 1 2023, In: Journal of the American Chemical Society. 145, 4, p. 2230-2242 13 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Refinement of Leishmania donovani Genome Annotations in the Light of Ribosome-Protected mRNAs Fragments (Ribo-Seq Data)
Sánchez-Salvador, A., González-de la Fuente, S., Aguado, B., Yates, P. A. & Requena, J. M., Aug 2023, In: Genes. 14, 8, 1637.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural diversity of photoswitchable sphingolipids for optodynamic control of lipid microdomains
Hartrampf, N., Leitao, S. M., Winter, N., Toombs-Ruane, H., Frank, J. A., Schwille, P., Trauner, D. & Franquelim, H. G., Jun 6 2023, In: Biophysical Journal. 122, 11, p. 2325-2341 17 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
The ubiquitin-specific protease USP36 SUMOylates EXOSC10 and promotes the nucleolar RNA exosome function in rRNA processing
Chen, Y., Li, Y., Dai, R. S., Savage, J. C., Shinde, U., Klimek, J., David, L. L., Young, E. A., Hafner, M., Sears, R. C., Sun, X. X. & Dai, M. S., May 8 2023, In: Nucleic acids research. 51, 8, p. 3934-3949 16 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
2022
A clickable photoaffinity probe of betulinic acid identifies tropomyosin as a target
Martín-Acosta, P., Meng, Q., Klimek, J., Reddy, A. P., David, L., Petrie, S. K., Li, B. X. & Xiao, X., May 2022, In: Acta Pharmaceutica Sinica B. 12, 5, p. 2406-2416 11 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
ADP-ribosyltransferases, an update on function and nomenclature
Lüscher, B., Ahel, I., Altmeyer, M., Ashworth, A., Bai, P., Chang, P., Cohen, M., Corda, D., Dantzer, F., Daugherty, M. D., Dawson, T. M., Dawson, V. L., Deindl, S., Fehr, A. R., Feijs, K. L. H., Filippov, D. V., Gagné, J. P., Grimaldi, G., Guettler, S., Hoch, N. C., & 27 others, Dec 2022, In: FEBS Journal. 289, 23, p. 7399-7410 12 p.Research output: Contribution to journal › Article › peer-review
Open Access131 Scopus citations -
Allosteric regulation of DNA binding and target residence time drive the cytotoxicity of phthalazinone-based PARP-1 inhibitors
Arnold, M. R., Langelier, M. F., Gartrell, J., Kirby, I. T., Sanderson, D. J., Bejan, D. S., Šileikytė, J., Sundalam, S. K., Nagarajan, S., Marimuthu, P., Duell, A. K., Shelat, A. A., Pascal, J. M. & Cohen, M. S., Dec 15 2022, In: Cell Chemical Biology. 29, 12, p. 1694-1708.e10Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Analysis of Rod/Cone Gap Junctions from the Reconstruction of Mouse Photoreceptor Terminals
Ishibashi, M., Keung, J., Morgans, C. W., Aicher, S. A., Carroll, J. R., Singer, J. H., Jia, L., Li, W., Fahrenfort, I., Ribelayga, C. P. & Massey, S. C., Apr 2022, In: eLife. 11, e73039.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Androgen receptors immunoreactivity in the rat brain of males with same-sex preference
Fernández-Guasti, A., Quintanar, B. G., Reyes, R., Hernández, A., Chavira, R. & Roselli, C. E., Nov 2022, In: Hormones and Behavior. 146, 105279.Research output: Contribution to journal › Article › peer-review
3 Scopus citations -
An Iron(III) Superoxide Corrole from Iron(II) and Dioxygen
Sacramento, J. J. D., Albert, T., Siegler, M., Moënne-Loccoz, P. & Goldberg, D. P., Jan 10 2022, In: Angewandte Chemie - International Edition. 61, 2, e202111492.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Changes in Microbiome Dominance Are Associated With Declining Lung Function and Fluctuating Inflammation in People With Cystic Fibrosis
Frey, D. L., Bridson, C., Dittrich, S., Graeber, S. Y., Stahl, M., Wege, S., Herth, F., Sommerburg, O., Schultz, C., Dalpke, A., Mall, M. A. & Boutin, S., May 13 2022, In: Frontiers in Microbiology. 13, 885822.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Control of coronary vascular resistance by eicosanoids via a novel GPCR
Kaul, S., Barnes, A. P., Alkayed, N. J., Cao, Z., Qian, Z. Y., Nagarajan, S., Liu, X., Nelson, J. W., Xie, F., Li, B., Fan, W., Liu, L., Grafe, M. R., Xiao, X. & Davis, C. M., May 2022, In: American Journal of Physiology - Cell Physiology. 322, 5, p. C1011-C1021Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Copper monooxygenase reactivity: Do consensus mechanisms accurately reflect experimental observations?
Welch, E. F., Rush, K. W., Arias, R. J. & Blackburn, N. J., Jun 2022, In: Journal of Inorganic Biochemistry. 231, 111780.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
CRISPR/SaCas9 mutagenesis of stromal interaction molecule 1 in proopiomelanocortin neurons increases glutamatergic excitability and protects against diet-induced obesity
Qiu, J., Bosch, M. A., Stincic, T. L., Hunker, A. C., Zweifel, L. S., Rønnekleiv, O. K. & Kelly, M. J., Dec 2022, In: Molecular Metabolism. 66, 101645.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Design, Synthesis and Biological Evaluation of Prodrugs of 666-15 as Inhibitors of CREB-Mediated Gene Transcription
Peng, J., Miller, M., Li, B. X. & Xiao, X., Mar 10 2022, In: ACS Medicinal Chemistry Letters. 13, 3, p. 388-395 8 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Direct Reduction of NO to N2O by a Mononuclear Nonheme Thiolate Ligated Iron(II) Complex via Formation of a Metastable {FeNO}7Complex
Dey, A., Albert, T., Kong, R. Y., Macmillan, S. N., Moënne-Loccoz, P., Lancaster, K. M. & Goldberg, D. P., Sep 26 2022, In: Inorganic Chemistry. 61, 38, p. 14909-14917 9 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Distinct roles for the Charcot-Marie-Tooth disease-causing endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and Schwann cell myelination
Mammel, A. E., Delgado, K. C., Chin, A. L., Condon, A. F., Hill, J. Q., Aicher, S. A., Wang, Y., Fedorov, L. M. & Robinson, F. L., Apr 15 2022, In: Human molecular genetics. 31, 8, p. 1216-1229 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Distinct roles of the Na+ binding sites in the allosteric coupling mechanism of the glutamate transporter homolog, GltPh
Riederer, E. A., Moënne-Loccoz, P. & Valiyaveetil, F. I., May 10 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 19, e2121653119.Research output: Contribution to journal › Article › peer-review
Open Access -
Effects of ex vivo blood anticoagulation and preanalytical processing time on the proteome content of platelets
Tassi Yunga, S., Gower, A. J., Melrose, A. R., Fitzgerald, M. K., Rajendran, A., Lusardi, T. A., Armstrong, R. J., Minnier, J., Jordan, K. R., McCarty, O. J. T., David, L. L., Wilmarth, P. A., Reddy, A. P. & Aslan, J. E., Jun 2022, In: Journal of Thrombosis and Haemostasis. 20, 6, p. 1437-1450 14 p.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Hypothalamic Kisspeptin Neurons and the Control of Homeostasis
Rønnekleiv, O. K., Qiu, J. & Kelly, M. J., Feb 1 2022, In: Endocrinology. 163, 2, bqab253.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
Identification of differential hypothalamic DNA methylation and gene expression associated with sexual partner preferences in rams
Bhattacharya, S., Amodei, R., Vilain, E. & Roselli, C. E., May 2022, In: PloS one. 17, 5 May, e0263319.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Influence of the Interdomain Interface on Structural and Redox Properties of Multiheme Proteins
Zhong, F., Albert, T., Moënne-Loccoz, P. & Pletneva, E. V., Dec 26 2022, In: Inorganic Chemistry. 61, 51, p. 20949-20963 15 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Insight into the Spatial Arrangement of the Lysine Tyrosylquinone and Cu2+ in the Active Site of Lysyl Oxidase-like 2
Meier, A. A., Moon, H. J., Sabuncu, S., Singh, P., Ronnebaum, T. A., Ou, S., Douglas, J. T., Jackson, T. A., Moënne-Loccoz, P. & Mure, M., Nov 2022, In: International journal of molecular sciences. 23, 22, 13966.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Mechanism of substrate inhibition in cytochrome-c dependent NO reductases from denitrifying bacteria (cNORs)
Matsumura, H., Faponle, A. S., Hagedoorn, P. L., Tosha, T., de Visser, S. P. & Moënne-Loccoz, P., Jun 2022, In: Journal of Inorganic Biochemistry. 231, 111781.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Molecular-Scale Dynamics of Long Range Retrograde Brain-Derived Neurotrophic Factor Transport Shaped by Cellular Spatial Context
Vermehren-Schmaedick, A., Olah, M. J., Ramunno-Johnson, D., Lidke, K. A., Cohen, M. S. & Vu, T. Q., Mar 31 2022, In: Frontiers in Neuroscience. 16, 835815.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations