Chemical Physiology and Biochemistry

Research output

Research output per year 1980 2001 2003 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2024

• 1273 Article
• 71 Review article
• 36 Chapter
• 27 Comment/debate
• 26 More
  • 9 Editorial
  • 8 Letter
  • 6 Short survey
  • 2 Conference contribution
  • 1 Paper

Research output per year

Research output per year

Search results

• 2023

  Quantification of PARP7 Protein Levels and PARP7 Inhibitor Target Engagement in Cells Using a Split Nanoluciferase System

  Duell, A. K., Sanderson, D. J. & Cohen, M. S., 2023, Methods in Molecular Biology. Humana Press Inc., p. 387-395 9 p. (Methods in Molecular Biology; vol. 2609).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • Proteins 100%
  • ADP-Ribosylation 74%
  • Interferon Type I 64%
  • Proteasome Endopeptidase Complex 56%
  • Western Blotting 37%

• Voltage-Gated Potassium Channels

  Valiyaveetil, F. I., Jan 1 2023, Textbook of Ion Channels Volume II: Properties, Function, and Pharmacology of the Superfamilies. CRC Press, p. 51-66 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Voltage-Gated Potassium Channels 100%
  • Membrane Potentials 37%
  • Muscle Cells 34%
  • Action Potentials 34%
  • Pharmacology 25%
• 2022

  How Structural Biology Has Directly Impacted Our Understanding of P2X Receptor Function and Gating

  Mansoor, S. E., 2022, Methods in Molecular Biology. Humana Press Inc., p. 1-29 29 p. (Methods in Molecular Biology; vol. 2510).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Purinergic P2X7 Receptors 100%
  • X Ray Crystallography 27%
  • X-Rays 23%
  • Ion Channels 20%
  • Electron Microscopy 17%
  6 Scopus citations
• 2021

  GPCRs at Endosomes: Sorting, Signaling, and Recycling

  Irannejad, R. & Lobingier, B. T., Jan 1 2021, GPCRs as Therapeutic Targets. wiley, Vol. 1. p. 180-196 17 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Recycling 100%
  • Endosomes 97%
  • Shape 56%
  • Complement System Proteins 54%
  • Plasma 53%
• 2020

  Estradiol Protects Hypothalamic Neurons Against Insulin Resistance

  Rønnekleiv, O. K. & Kelly, M. J., Jan 1 2020, Stress: Genetics, Epigenetics and Genomics Volume 4: Handbook of Stress. Elsevier, p. 159-166 8 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Estradiol 100%
  • Insulin Resistance 93%
  • Sex Characteristics 71%
  • Neurons 70%
  • Metabolic Syndrome 70%
  1 Scopus citations

• Photo-releasable derivatives of inositol pyrophosphates

  Hauke, S., Bittner, T., Jessen, H. J. & Schultz, C., 2020, Chemical Tools for Imaging, Manipulating, and Tracking Biological Systems: Diverse Chemical, Optical and Bioorthogonal Methods. Chenoweth, D. M. (ed.). Academic Press Inc., p. 53-73 21 p. (Methods in Enzymology; vol. 641).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Diphosphates 100%
  • Inositol 89%
  • Calcium(0) 57%
  • Insulin Derivative 38%
  • Calcium Signaling 29%
  2 Scopus citations
• 2019

  CHAPTER 16: Mechanisms of Nitric Oxide Sensing and Detoxification by Bacterial Hemoproteins

  Moënne-Loccoz, P., Yukl, E. T. & Matsumura, H., 2019, Dioxygen-dependent Heme Enzymes. Ikeda-Saito, M. & Raven, E. (eds.). 13 ed. Royal Society of Chemistry, p. 351-369 19 p. (RSC Metallobiology; vol. 2019-January, no. 13).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Hemoprotein 100%
  • Nitric Oxide 74%
  • nitric-oxide reductase 40%
  • Heme 24%
  • nitric oxide dioxygenase 22%

• Small-molecule inhibitors of PARPS: from tools for investigating ADP-ribosylation to therapeutics

  Kirby, I. T. & Cohen, M. S., 2019, Current Topics in Microbiology and Immunology. Springer-Verlag, p. 211-231 21 p. (Current Topics in Microbiology and Immunology; vol. 420).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • ADP-Ribosylation 100%
  • Poly(ADP-ribose) Polymerase Inhibitors 96%
  • Polypharmacology 60%
  • Poly(ADP-ribose) Polymerases 43%
  • History 27%
  21 Scopus citations

• Visualization of intracellular hydrogen peroxide with the genetically encoded fluorescent probe HyPer in NIH-3T3 cells

  Ermakova, Y. G., Mishina, N. M., Schultz, C. & Belousov, V. V., 2019, Methods in Molecular Biology. Humana Press Inc., p. 259-274 16 p. (Methods in Molecular Biology; vol. 1982).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • NIH 3T3 Cells 100%
  • Fluorescent Dyes 81%
  • Hydrogen Peroxide 77%
  • D-Amino-Acid Oxidase 64%
  • Reactive Oxygen Species 62%
  5 Scopus citations
• 2018

  A simple, sensitive, and generalizable plate assay for screening PARP inhibitors

  Kirby, I. T., Morgan, R. K. & Cohen, M. S., 2018, Methods in Molecular Biology. Humana Press Inc., p. 245-252 8 p. (Methods in Molecular Biology; vol. 1813).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Poly(ADP-ribose) Polymerase Inhibitors 100%
  • Enzymes 41%
  • ADP Ribose Transferases 37%
  • ADP-Ribosylation 34%
  • Unfolded Protein Response 31%
  3 Scopus citations

• Methods for characterizing disease-associated ATP-sensitive potassium channel mutations

  Kandasamy, B. & Shyng, S. L., 2018, Methods in Molecular Biology. Humana Press Inc., p. 85-104 20 p. (Methods in Molecular Biology; vol. 1684).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • KATP Channels 100%
  • Sulfonylurea Receptors 80%
  • Developmental Delay, Epilepsy, and Neonatal Diabetes 54%
  • Insulin Secretion 52%
  • Mutation 44%
  5 Scopus citations

• Methods for using a genetically encoded fluorescent biosensor to monitor nuclear NAD ⁺

  Cohen, M. S., Stewart, M. L., Goodman, R. H. & Cambronne, X. A., 2018, Methods in Molecular Biology. Humana Press Inc., p. 391-414 24 p. (Methods in Molecular Biology; vol. 1813).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • Biosensing Techniques 100%
  • NAD 84%
  • Guidelines 10%
  • Enzymes 8%
  6 Scopus citations

• Patch-clamp recordings of the KcsA K⁺ channel in unilamellar blisters

  Matulef, K. & Valiyaveetil, F. I., 2018, Methods in Molecular Biology. Humana Press Inc., p. 181-191 11 p. (Methods in Molecular Biology; vol. 1684).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • Blister 100%
  • Ion Channels 93%
  • Unilamellar Liposomes 26%
  • Electrophysiology 21%
  • Xenopus 20%
  3 Scopus citations

• Probing Subunits Interactions in K_ATP Channels Using Photo-Crosslinking via Genetically Encoded p-Azido-l-phenylalanine

  Devaraneni, P., Rex, E. A. & Shyng, S. L., 2018, Methods in Molecular Biology. Humana Press Inc., p. 51-61 11 p. (Methods in Molecular Biology; vol. 1684).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • KATP Channels 100%
  • Phenylalanine 86%
  • Ligands 55%
  • Potassium Channels 45%
  • Sulfonylurea Receptors 30%
  1 Scopus citations

• Quantification of thyromimetic sobetirome concentration in biological tissue samples

  Devereaux, J., Ferrara, S. J. & Scanlan, T. S., 2018, Methods in Molecular Biology. Humana Press Inc., p. 193-206 14 p. (Methods in Molecular Biology; vol. 1801).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • GC 1 compound 100%
  • Thyroid Hormones 56%
  • Tandem Mass Spectrometry 30%
  • Liquid Chromatography 29%
  • Vertebrates 25%
  3 Scopus citations
• 2017

  Analysis of the Proteome of Hair-Cell Stereocilia by Mass Spectrometry

  Krey, J. F., Wilmarth, P. A., David, L. L. & Barr-Gillespie, P. G., 2017, Methods in Enzymology. Academic Press Inc., p. 329-354 26 p. (Methods in Enzymology; vol. 585).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • Hair Analysis 100%
  • Stereocilia 99%
  • Proteome 69%
  • Mass Spectrometry 60%
  • Protein 27%
  4 Scopus citations

• Detecting protein ADP-ribosylation using a clickable aminooxy probe

  Morgan, R. K. & Cohen, M. S., 2017, Methods in Molecular Biology. Humana Press Inc., p. 71-77 7 p. (Methods in Molecular Biology; vol. 1608).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • ADP-Ribosylation 100%
  • Alkynes 47%
  • Acidic Amino Acids 43%
  • Proteins 26%
  • Azides 20%
  6 Scopus citations

• Purification of Functional CB₁ and Analysis by Site-Directed Fluorescence Labeling Methods

  Fay, J. F. & Farrens, D. L., 2017, Methods in Enzymology. Academic Press Inc., p. 343-370 28 p. (Methods in Enzymology; vol. 593).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • bimanes 100%
  • Cannabinoid 94%
  • Fluorescence 81%
  • Purification 67%
  • Cannabinoids 58%
  6 Scopus citations
• 2016

  Sexual differentiation of the brain

  Roselli, C. E., Jan 1 2016, The Curated Reference Collection in Neuroscience and Biobehavioral Psychology. Elsevier Science Ltd., p. 356-362 7 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Sex Differentiation 100%
  • Gonadotropins 52%
  • Testosterone 44%
  • Brain 37%
  • Gonadal Steroid Hormones 27%
• 2014

  Estradiol and Kisspeptin Modulation of Gonadotropin-Releasing Hormone (GnRH) Neuronal Excitability

  Rønnekleiv, O. K., Zhang, C. & Kelly, M. J., Oct 6 2014, Neurophysiology of Neuroendocrine Neurons. wiley, p. 301-321 21 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Kisspeptins 100%
  • Gonadotropin-Releasing Hormone 69%
  • Estradiol 60%
  • Neurons 42%
  • KATP Channels 20%
  2 Scopus citations
• 2013

  Engineering K⁺ channels using semisynthesis

  Komarov, A. G., Costantino, C. A. & Valiyaveetil, F. I., 2013, Chemical Neurobiology: Methods and Protocols. Banghart, M. (ed.). p. 3-17 15 p. (Methods in Molecular Biology; vol. 995).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Potassium Channels 100%
  • Site-Directed Mutagenesis 93%
  • Membrane Proteins 72%
  • Ions 72%
  • Binding Sites 67%
  4 Scopus citations

• Kisspeptin excitation of GnRH neurons

  Rønnekleiv, O. K. & Kelly, M. J., 2013, Kisspeptin Signaling in Reproductive Biology. Springer New York LLC, p. 113-131 19 p. (Advances in Experimental Medicine and Biology; vol. 784).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  Open Access

  • Kisspeptins 100%
  • Gonadotropin-Releasing Hormone 69%
  • Neurons 42%
  • Depolarization 12%
  • Cations 11%
  30 Scopus citations

• The Distribution and Regulation of Aromatase in the Mammalian Brain: from Mice to Monkeys

  Roselli, C. E., Jan 24 2013, Brain Aromatase, Estrogens, and Behavior. Oxford University Press

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Aromatase 100%
  • Haplorhini 75%
  • Estrogens 67%
  • Brain 39%
  • Gonads 15%
  7 Scopus citations
• 2012

  Metal Export by CusCFBA, the Periplasmic Cu(I)/Ag(I) Transport System of Escherichia coli

  Mealman, T. D., Blackburn, N. J. & McEvoy, M. M., 2012, Current Topics in Membranes. Academic Press Inc., p. 163-196 34 p. (Current Topics in Membranes; vol. 69).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Metals 100%
  • Escherichia coli 81%
  • Ions 41%
  • Metallochaperones 30%
  • Periplasm 21%
  42 Scopus citations

• Molecular defects of ATP-sensitive potassium channels in congenital hyperinsulinism

  Shyng, S. L., Bushman, J. D., Pratt, E. B. & Zhou, Q., Feb 16 2012, Monogenic Hyperinsulinemic Hypoglycemia Disorders. S. Karger AG, Vol. 21. p. 30-42 13 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Congenital Hyperinsulinism 100%
  • KATP Channels 81%
  • Sulfonylurea Receptors 24%
  • Inwardly Rectifying Potassium Channels 22%
  • Insulin Derivative 21%
  2 Scopus citations
• 2011

  Anatomical, physiological, and behavioral analysis of rodent vision

  Jeffrey, B. G., McGill, T. J., Haley, T. L., Morgans, C. W. & Duvoisin, R. M., 2011, Animal Models of Behavioral Analysis. Raber, J. (ed.). p. 29-54 26 p. (Neuromethods; vol. 50).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Signalling Molecule 100%
  • Neurotransmitter 88%
  • Ocular Vision 66%
  • Rodentia 65%
  • Optokinetic Nystagmus 39%
  2 Scopus citations
• 2010

  Normal age-related changes: Crystallin modifications, lens hardening

  Wilmarth, P., David, L. & Lampi, K., Jan 1 2010, Encyclopedia of the Eye. Elsevier, p. 161-166 6 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Crystallins 100%
  • Lenses 72%
  • Post Translational Protein Processing 39%
  • Age-Related Nuclear Cataract 35%
  • Presbyopia 29%
  2 Scopus citations
• 2009

  Biogenesis and degradation of gap junctions

  Musil, L. S., 2009, Connexins: A Guide. Humana Press Inc., p. 225-240 16 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Connexins 100%
  • Gap Junctions 91%
  • Reaction Half Life 76%
  • Communication 72%
  • Endoplasmic Reticulum 57%
  8 Scopus citations

• Chapter 7 Semisynthesis of K⁺ Channels

  Komarov, A. G., Linn, K. M., Devereaux, J. J. & Valiyaveetil, F. I., 2009, Methods in Enzymology. Muir, T. & Abelson, J. (eds.). p. 135-150 16 p. (Methods in Enzymology; vol. 462).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Ions 100%
  • Site-Directed Mutagenesis 86%
  • Binding Sites 62%
  • Binding Site 42%
  • Ion 35%
  4 Scopus citations

• Membrane-initiated effects of estrogen in the central nervous system

  Rnnekleiv, O. K. & Kelly, M. J., 2009, Hormones, Brain and Behavior Online. Elsevier Inc., p. 1099-1122 24 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Estrogens 100%
  • Central Nervous System 89%
  • Membranes 72%
  • Intracellular Membranes 25%
  • Neurons 24%
• 2008

  Purine and pyrimidine metabolism in Leishmania

  Ullman, B., Carter, N., Yates, P., Arendt, C. S. & Boitz, J. M., 2008, Drug Targets in Kinetoplastid Parasites. Springer New York, p. 141-154 14 p. (Advances in Experimental Medicine and Biology; vol. 625).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • pyrimidine 100%
  • Leishmania 94%
  • purine 93%
  • Purine 82%
  • Pyrimidine 72%
  85 Scopus citations
• 2005

  Estrogen Signaling in the Hypothalamus

  Kelly, M. J., Qiu, J. & Rønnekleiv, O. K., 2005, Vitamins and Hormones. Litwack, G. (ed.). p. 123-145 23 p. (Vitamins and Hormones; vol. 71).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Hypothalamus 100%
  • Estrogens 88%
  • Neurons 18%
  • Nuclear Envelope 17%
  • Reproduction 14%
  45 Scopus citations

• Structural dynamics of the signal termination process in rhodopsin

  Farrens, D. L., 2005, Light Sensing in Plants. Springer Japan, Vol. 9784431270928. p. 203-212 10 p.

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Rhodopsin 100%
  • rhodopsin 96%
  • arrestins 61%
  • Arrestin 57%
  • Light Signal Transduction 56%
• 2004

  ATP-sensitive potassium channels and insulin secretion diseases

  Nichols, C. G., Shyng, S. L., Marshall, B. & Koster, J. C., 2004, Molecular Insights into Ion Channel Biology in Health and Disease. Academic Press Inc., p. 1-14 14 p. (Advances in Molecular and Cell Biology; vol. 32).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
• 1994

  Electrophysiological Analysis of Neuroendocrine Neuronal Activity in Hypothalamic Slices

  Kelly, M. J. & Ronnekleiv, O., Jan 1 1994, Methods in Neurosciences. C ed. p. 47-67 21 p. (Methods in Neurosciences; vol. 20, no. C).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter

  • Neurons 100%
  • biocytin 81%
  • Afferent Pathways 74%
  • Pharmacology 72%
  • Phenotype 65%
  22 Scopus citations
• 1991

  Progonadotropin-Releasing Hormone Synthesis and Processing: Measurements of mRNA and Peptides

  Ronnekleiv, O., Bosch, M. A., Naylor, B. R. & Kelly, M. J., Jan 1 1991, Methods in Neurosciences. C ed. p. 85-108 24 p. (Methods in Neurosciences; vol. 5, no. C).

  Research output: Chapter in Book/Report/Conference proceeding › Chapter
  8 Scopus citations