Pacific Northwest Center for Cryo-EM (PNCC)

Research output

Research output per year 2002 2017 2018 2019 2020 2024

• 49 Article
• 3 Review article
• 2 Chapter
• 2 Comment/debate

Research output per year

Research output per year

Search results

• 2024

  Autotaxin–lysolipid signaling suppresses a CCL11–eosinophil axis to promote pancreatic cancer progression

  Bhattacharyya, S., Oon, C., Diaz, L., Sandborg, H., Stempinski, E. S., Saoi, M., Morgan, T., López, C. S., Cross, J. R. & Sherman, M., Feb 2024, In: Nature Cancer. 5, 2, p. 283-298 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  2 Scopus citations
• 2023

  Large-Scale Electron Microscopy to Find Nanoscale Detail in Cancer

  Riesterer, J. L., Bueno, C., Stempinski, E. S., Adamou, S. K., López, C. S., Thibault, G., Pagano, L., Grieco, J., Olson, S., Machireddy, A., Chang, Y. H., Song, X. & Gray, J. W., Jul 22 2023, In: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 29, 1, p. 1078-1079 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Novel Genetically Encoded Peptide Tags for Correlative Imaging: Lessons Learned

  López, C. S., Devlin, K., Stempinski, E. S. & Beatty, K. E., Jul 22 2023, In: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 29, 1, p. 2099 1 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2022

  INHBA is a mediator of aggressive tumor behavior in HER2+ basal breast cancer

  Liu, M., Smith, R., Liby, T., Chiotti, K., López, C. S. & Korkola, J. E., Dec 2022, In: Breast Cancer Research. 24, 1, 18.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Breast Neoplasms 100%
  • Lapatinib 88%
  • Gene Knockdown Techniques 81%
  • Neoplasms 50%
  • Disease Resistance 42%
  4 Scopus citations

• Reduced Proteolytic Cleavage of von Willebrand Factor Leads to Aortic Valve Stenosis and Load-Dependent Ventricular Remodeling

  Ozawa, K., Muller, M. A., Varlamov, O., Hagen, M. W., Packwood, W., Morgan, T. K., Xie, A., López, C. S., Chung, D., Chen, J., López, J. A. & Lindner, J. R., Jul 2022, In: JACC: Basic to Translational Science. 7, 7, p. 642-655 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ventricular Remodeling 100%
  • Aortic Valve Stenosis 92%
  • von Willebrand Factor 92%
  • Blood Platelets 65%
  • Molecular Imaging 24%
  4 Scopus citations
• 2020

  Adeno-associated virus (AAV-DJ)—Cryo-EM structure at 1.56 Å resolution

  Xie, Q., Yoshioka, C. K. & Chapman, M. S., Oct 20 2020, In: Viruses. 12, 10, 1194.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cryoelectron Microscopy 100%
  • Dependovirus 91%
  • Hydrogen Bonding 88%
  • Hydrogen 56%
  • Preprints 41%
  19 Scopus citations

• Comparison of 3D Protocols in Metastatic Breast Cancer Tumors

  Stempinski, E., Riesterer, J., Bleck, C. K. E., Lopez, C. & Gray, J., 2020, (Accepted/In press) In: Microscopy and Microanalysis. 519.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 Å

  Flores, J. A., Haddad, B. G., Dolan, K. A., Myers, J. B., Yoshioka, C. C., Copperman, J., Zuckerman, D. M. & Reichow, S. L., Dec 1 2020, In: Nature communications. 11, 1, 4331.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • connexin 46 100%
  • connexin 50 98%
  • lipids 50%
  • Lipid 35%
  • Lipids 33%
  54 Scopus citations

• Imaging Bioprinted Model Systems for Metastatic Breast Cancer Studies

  Riesterer, J., Singh, A., Stempinski, E., Adamou, S., Bueno, C., Smith, H., Lopez, C. & Gray, J., 2020, (Accepted/In press) In: Microscopy and Microanalysis. 536.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Multiscale cardiac imaging spanning the whole heart and its internal cellular architecture in a small animal model

  Rykiel, G., López, C. S., Riesterer, J. L., Fries, I., Deosthali, S., Courchaine, K., Maloyan, A., Thornburg, K. & Rugonyi, S., Oct 2020, In: eLife. 9, p. 1-26 26 p., e58138.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Animal Models 100%
  • Heart 89%
  • Scanning Electron Microscopy 82%
  • Three-Dimensional Imaging 40%
  • Congenital Heart Defects 40%
  7 Scopus citations

• Structure of the Cardiac Sodium Channel

  Jiang, D., Shi, H., Tonggu, L., Gamal El-Din, T. M., Lenaeus, M. J., Zhao, Y., Yoshioka, C., Zheng, N. & Catterall, W. A., Jan 9 2020, In: Cell. 180, 1, p. 122-134.e10

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antiarrhythmic Agent 100%
  • Sodium Channels 85%
  • Anti-Arrhythmia Agents 83%
  • Cardiac Arrhythmias 61%
  • Ions 59%
  177 Scopus citations

• Trans-synaptic and retrograde axonal spread of Lewy pathology following pre-formed fibril injection in an in vivo A53T alpha-synuclein mouse model of synucleinopathy

  Schaser, A. J., Stackhouse, T. L., Weston, L. J., Kerstein, P. C., Osterberg, V. R., López, C. S., Dickson, D. W., Luk, K. C., Meshul, C. K., Woltjer, R. L. & Unni, V. K., Aug 28 2020, In: Acta Neuropathologica Communications. 8, 1, 150.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Mouse Snca protein 100%
  • Synucleinopathies 79%
  • alpha-Synuclein 68%
  • Pathology 36%
  • Injections 32%
  30 Scopus citations
• 2019

  Fgf2-fgfr1 signaling regulates release of leukemia-protective exosomes from bone marrow stromal cells

  Javidi-Sharifi, N., Martinez, J., English, I., Joshi, S. K., Scopim-Ribiero, R., Edwards V, D. K., Agarwal, A., Lopez, C., Jorgens, D., Tyner, J. W., Druker, B. J. & Traer, E., Feb 2019, In: eLife. 8, e40033.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Exosomes 100%
  • Tyrosine Kinase Inhibitor 88%
  • Mesenchymal Stem Cells 76%
  • Leukemia 69%
  • Fibroblast Growth Factor 2 45%
  52 Scopus citations

• Full-Length P2X₇ Structures Reveal How Palmitoylation Prevents Channel Desensitization

  McCarthy, A. E., Yoshioka, C. & Mansoor, S. E., Oct 17 2019, In: Cell. 179, 3, p. 659-670.e13

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Palmitoyl Group 100%
  • Palmitoylation 93%
  • Lipoylation 81%
  • Purinergic P2X7 Receptors 81%
  • Apoptotic 65%
  147 Scopus citations

• HOTSPUR: A Real-time Interactive Preprocessing System for Cryo-EM Data

  Elferich, J., Posert, R., Yoshioka, C. & Gouaux, E., Aug 1 2019, In: Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 25, p. 1212-1213 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access
  1 Scopus citations

• Imaging viper-labeled cellular proteins by correlative light and electron microscopy

  Doh, J. K., Chang, Y. H., Enns, C. A., Lopez, C. S. & Beatty, K. E., Nov 5 2019, In: Bio-protocol. 9, 21, e3414.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Viperidae 100%
  • Optical Microscopy 68%
  • light microscopy 67%
  • Electron Microscopy 67%
  • Microscopy 64%
  4 Scopus citations

• Mechanism of pharmacochaperoning in a mammalian K_ATP channel revealed by cryo-EM

  Martin, G. M., Sung, M. W., Yang, Z., Innes, L. M., Kandasamy, B., David, L. L., Yoshioka, C. & Shyng, S. L., Jul 2019, In: eLife. 8, e46417.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sulfonylurea Receptors 100%
  • KATP Channels 83%
  • Repaglinide 54%
  • Carbamazepine 40%
  • Drug 34%
  59 Scopus citations

• Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport

  Coleman, J. A., Yang, D., Zhao, Z., Wen, P. C., Yoshioka, C., Tajkhorshid, E. & Gouaux, E., May 2 2019, In: Nature. 569, 7754, p. 141-145 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ibogaine 100%
  • Plasma Membrane Neurotransmitter Transport Proteins 54%
  • Serotonin Plasma Membrane Transport Proteins 53%
  • Serotonin 49%
  • Psychological Inhibition 46%
  156 Scopus citations

• Structure of the gene therapy vector, adeno-associated virus with its cell receptor, aavr

  Meyer, N. L., Hu, G., Davulcu, O., Xie, Q., Noble, A. J., Yoshioka, C., Gingerich, D. S., Trzynka, A., David, L., Stagg, S. M. & Chapman, M. S., May 2019, In: eLife. 8, e44707.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Dependovirus 100%
  • Neutralization 81%
  • Genetic Therapy 74%
  • Electron Microscope Tomography 59%
  • Virus Receptors 55%
  53 Scopus citations
• 2018

  Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABA_A receptor in complex with GABA

  Phulera, S., Zhu, H., Yu, J., Claxton, D. P., Yoder, N., Yoshioka, C. & Gouaux, E., Jul 25 2018, In: eLife. 7, e39383.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • GABA-A Receptors 100%
  • Benzodiazepines 95%
  • Sedative Agent 65%
  • Anaesthetic 57%
  • Anticonvulsant 54%
  102 Scopus citations

• Gating mechanisms of acid-sensing ion channels

  Yoder, N., Yoshioka, C. & Gouaux, E., Mar 15 2018, In: Nature. 555, 7696, p. 397-401 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Acid Sensing Ion Channels 100%
  • Thumb 29%
  • Protons 26%
  • Chickens 25%
  • Degenerin Sodium Channels 22%
  144 Scopus citations

• Glycan shield and fusion activation of a deltacoronavirus spike glycoprotein fine-tuned for enteric infections

  Xiong, X., Tortorici, M. A., Snijder, J., Yoshioka, C., Walls, A. C., Li, W., McGuire, A. T., Rey, F. A., Bosch, B. J. & Veesler, D., Feb 1 2018, In: Journal of virology. 92, 4, e01628-17.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Deltacoronavirus 100%
  • Coronavirus 69%
  • Polysaccharides 51%
  • Glycoproteins 47%
  • glycoproteins 46%
  102 Scopus citations

• Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor

  Jalali-Yazdi, F., Chowdhury, S., Yoshioka, C. & Gouaux, E., Nov 29 2018, In: Cell. 175, 6, p. 1520-1532.e15

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Protons 100%
  • N-Methyl-D-Aspartate Receptors 98%
  • Zinc 94%
  • Psychological Inhibition 80%
  • Proton 63%
  77 Scopus citations

• Structure of native lens connexin 46/50 intercellular channels by cryo-EM

  Myers, J. B., Haddad, B. G., O’Neill, S. E., Chorev, D. S., Yoshioka, C. C., Robinson, C. V., Zuckerman, D. M. & Reichow, S. L., Dec 20 2018, In: Nature. 564, 7736, p. 372-377 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • connexin 46 100%
  • connexin 50 98%
  • Connexins 64%
  • Gap Junctions 59%
  • Connexin 26 52%
  89 Scopus citations

• Structure of the human epithelial sodium channel by cryo-electron microscopy

  Noreng, S., Bharadwaj, A., Posert, R., Yoshioka, C. & Baconguis, I., Sep 2018, In: eLife. 7, e39340.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cryoelectron Microscopy 100%
  • Epithelial Sodium Channels 99%
  • Cryo-Electron Microscopy 96%
  • Thumb 83%
  • Fingers 67%
  119 Scopus citations
• 2017

  Anti-diabetic drug binding site in a mammalian K_ATP channel revealed by Cryo-EM

  Martin, G. M., Kandasamy, B., Dimaio, F., Yoshioka, C. & Shyng, S. L., Oct 16 2017, In: eLife. 6, e31054.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • KATP Channels 100%
  • Antidiabetic Agent 96%
  • Glyburide 92%
  • Binding Sites 60%
  • Binding Site 55%
  111 Scopus citations

• Cryo-EM structure of the ATP-sensitive potassium channel illuminates mechanisms of assembly and gating

  Martin, G. M., Yoshioka, C., Rex, E. A., Fay, J. F., Xie, Q., Whorton, M. R., Chen, J. Z. & Shyng, S. L., Jan 16 2017, In: eLife. 6, e24149.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • KATP Channels 100%
  • Glyburide 61%
  • Insulin Derivative 26%
  • Insulin Secretion 26%
  • Hypoglycemic Agents 25%
  136 Scopus citations

• Deep nuclear invaginations are linked to cytoskeletal filaments - integrated bioimaging of epithelial cells in 3D culture

  Jorgens, D. M., Inman, J. L., Wojcik, M., Robertson, C., Palsdottir, H., Tsai, W. T., Huang, H., Bruni-Cardoso, A., López, C. S., Bissell, M. J., Xu, K. & Auer, M., 2017, In: Journal of Cell Science. 130, 1, p. 177-189 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hemidesmosomes 100%
  • Cytoskeleton 99%
  • Desmosomes 86%
  • Epithelial Cells 71%
  • Nuclear Envelope 37%
  63 Scopus citations

• Increased hemodynamic load in early embryonic stages alters endocardial to mesenchymal transition

  Midgett, M., López, C. S., David, L., Maloyan, A. & Rugonyi, S., Feb 8 2017, In: Frontiers in Physiology. 8, FEB, 56.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Hemodynamics 100%
  • Endocardium 44%
  • Heart 43%
  • Electron Scanning Microscopy 32%
  • Chickens 32%
  32 Scopus citations

• Increased hemodynamic load in early embryonic stages alters myofibril and mitochondrial organization in the myocardium

  Midgett, M., López, C. S., David, L., Maloyan, A. & Rugonyi, S., Aug 30 2017, In: Frontiers in Physiology. 8, AUG, 631.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Myocardium 69%
  • Hemodynamics 61%
  • Proteomics 57%
  • Heart 54%
  • Renin-Angiotensin System 21%
  13 Scopus citations

• Quantitating morphological changes in biological samples during scanning electron microscopy sample preparation with correlative super-resolution microscopy

  Zhang, Y., Huang, T., Jorgens, D. M., Nickerson, A., Lin, L. J., Pelz, J., Gray, J. W., López, C. S. & Nan, X., May 2017, In: PloS one. 12, 5, e0176839.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Electron Scanning Microscopy 100%
  • Microscopy 85%
  • Electron Microscopy 66%
  • Osmium Tetroxide 38%
  • Fibronectins 25%
  39 Scopus citations
• 2016

  Architecture of fully occupied GluA2 AMPA receptor-TARP complex elucidated by cryo-EM

  Zhao, Y., Chen, S., Yoshioka, C., Baconguis, I. & Gouaux, E., Jul 1 2016, In: Nature. 536, 7614, p. 108-111 4 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cryoelectron Microscopy 100%
  • AMPA Receptors 87%
  • Proteins 27%
  • Ligands 26%
  • Ion Channels 14%
  85 Scopus citations

• Mechanism of NMDA Receptor Inhibition and Activation

  Zhu, S., Stein, R. A., Yoshioka, C., Lee, C. H., Goehring, A., McHaourab, H. S. & Gouaux, E., Apr 21 2016, In: Cell. 165, 3, p. 704-714 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • N-Methyl-D-Aspartate Receptors 100%
  • Psychological Inhibition 81%
  • Agonist 63%
  • Cryo-Electron Microscopy 43%
  • Bound State 42%
  158 Scopus citations
• 2014

  3D imaging of the early embryonic chicken heart with focused ion beam scanning electron microscopy

  Rennie, M. Y., Gahan, C. G., López, C. S., Thornburg, K. L. & Rugonyi, S., Aug 2014, In: Microscopy and Microanalysis. 20, 4, p. 1111-1119 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Focused ion beams 100%
  • chickens 96%
  • Scanning electron microscopy 56%
  • ion beams 55%
  • Imaging techniques 55%
  9 Scopus citations

• RRE-dependent HIV-1 Env RNA effects on Gag protein expression, assembly and release

  López, C. S., Sloan, R., Cylinder, I., Kozak, S. L., Kabat, D. & Barklis, E., Aug 2014, In: Virology. 462-463, 1, p. 126-134 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • env Genes 100%
  • gag Gene Products 97%
  • HIV-1 62%
  • RNA 49%
  • Cell Nucleus Active Transport 42%
  8 Scopus citations
• 2010

  Role of the pJM1 plasmid-encoded transport proteins FatB, C and D in ferric anguibactin uptake in the fish pathogen Vibrio anguillarum

  Naka, H., López, C. S. & Crosa, J. H., Feb 2010, In: Environmental Microbiology Reports. 2, 1, p. 104-111 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • anguibactin 100%
  • Vibrio anguillarum 62%
  • Vibrio 62%
  • plasmid 59%
  • siderophores 55%
  14 Scopus citations
• 2009

  Molecular characterization of the TonB2 protein from the fish pathogen Vibrio anguillarum

  López, C. S., Peacock, R. S., Crosa, J. H. & Vogel, H. J., Feb 15 2009, In: Biochemical Journal. 418, 1, p. 49-59 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fish Proteins 100%
  • anguibactin 85%
  • Vibrio 79%
  • Escherichia coli 43%
  • Amino Acids 29%
  12 Scopus citations
• 2008

  Reactivation of the vanchrobactin siderophore system of Vibrio anguillarum by removal of a chromosomal insertion sequence originated in plasmid pJM1 encoding the anguibactin siderophore system

  Naka, H., López, C. S. & Crosa, J. H., Jan 2008, In: Environmental Microbiology. 10, 1, p. 265-277 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • vanchrobactin 100%
  • anguibactin 86%
  • siderophore 59%
  • Siderophores 58%
  • Vibrio anguillarum 54%
  37 Scopus citations
• 2007

  Characterization of ferric-anguibactin transport in Vibrio anguillarum

  López, C. S. & Crosa, J. H., Jun 2007, In: BioMetals. 20, 3-4, p. 393-403 11 p.

  Research output: Contribution to journal › Article › peer-review

  • anguibactin 100%
  • Siderophore 63%
  • Vibrio anguillarum 62%
  • Vibrio 62%
  • Fish 53%
  22 Scopus citations

• Identification of amino acid residues required for ferric-anguibactin transport in the outer-membrane receptor FatA of Vibrio anguillarum

  López, C. S., Alice, A. F., Chakraborty, R. & Crosa, J. H., Feb 2007, In: Microbiology. 153, 2, p. 570-584 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • anguibactin 100%
  • Vibrio 62%
  • Amino Acids 34%
  • Membranes 28%
  • Plasmids 19%
  16 Scopus citations
• 2006

  Genetic and transcriptional analysis of the siderophore malleobactin biosynthesis and transport genes in the human pathogen Burkholderia pseudomallei K96243

  Alice, A. F., López, C. S., Lowe, C. A., Ledesma, M. A. & Crosa, J. H., Feb 2006, In: Journal of bacteriology. 188, 4, p. 1551-1566 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Burkholderia pseudomallei 100%
  • Siderophores 96%
  • Iron 58%
  • Open Reading Frames 50%
  • Genes 28%
  54 Scopus citations

• Role of anionic phospholipids in the adaptation of Bacillus subtilis to high salinity

  López, C. S., Alice, A. F., Heras, H., Rivas, E. A. & Sánchez-Rivas, C., Mar 2006, In: Microbiology. 152, 3, p. 605-616 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Salinity 100%
  • Cardiolipins 84%
  • Bacillus subtilis 74%
  • Phospholipids 60%
  • Phosphatidylglycerols 53%
  88 Scopus citations
• 2005

  Human carbonic anhydrase III: Structural and kinetic study of catalysis and proton transfer

  Duda, D. M., Tu, C., Fisher, S. Z., An, H., Yoshioka, C., Govindasamy, L., Laipis, P. J., Agbandje-McKenna, M., Silverman, D. N. & McKenna, R., Aug 2 2005, In: Biochemistry. 44, 30, p. 10046-10053 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbonic Anhydrase III 100%
  • Catalysis 67%
  • Protons 57%
  • Proton Transfer 50%
  • Imidazole 48%
  66 Scopus citations

• Plasmid- and chromosome-encoded redundant and specific functions are involved in biosynthesis of the siderophore anguibactin in Vibrio anguillarum 775: A case of chance and necessity?

  Alice, A. F., López, C. S. & Crosa, J. H., Mar 2005, In: Journal of bacteriology. 187, 6, p. 2209-2214 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • anguibactin 100%
  • Siderophores 67%
  • Vibrio 62%
  • Plasmids 39%
  • Chromosomes 38%
  40 Scopus citations

• Structural and kinetic characterization of active-site histidine as a proton shuttle in catalysis by human carbonic anhydrase II

  Fisher, Z., Hernandez Prada, J. A., Tu, C., Duda, D., Yoshioka, C., An, H., Govindasamy, L., Silverman, D. N. & McKenna, R., Feb 1 2005, In: Biochemistry. 44, 4, p. 1097-1105 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbonic Anhydrase II 100%
  • Catalysis 78%
  • Histidine 72%
  • Protons 66%
  • Catalytic Domain 59%
  139 Scopus citations
• 2004

  Actin crystal dynamics: Structural implications for F-actin nucleation, polymerization, and branching mediated by the anti-parallel dimer

  Reutzel, R., Yoshioka, C., Govindasamy, L., Yarmola, E. G., Agbandje-McKenna, M., Bubb, M. R. & McKenna, R., Jun 2004, In: Journal of Structural Biology. 146, 3, p. 291-301 11 p.

  Research output: Contribution to journal › Article › peer-review

  • Polymerization 100%
  • Actins 82%
  • Cell Shape 11%
  • Actin Cytoskeleton 9%
  • Organelles 9%
  25 Scopus citations

• Osmotic response in Lactobacillus casei ATCC 393: Biochemical and biophysical characteristics of membrane

  Machado, M. C., López, C. S., Heras, H. & Rivas, E. A., Feb 1 2004, In: Archives of Biochemistry and Biophysics. 422, 1, p. 61-70 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Lactobacillus casei 100%
  • Fatty Acids 60%
  • Lipid 48%
  • Membranes 42%
  • laurdan 42%
  61 Scopus citations
• 2002

  Crystallization and preliminary X-ray analysis of human carbonic anhydrase III

  Duda, D. M., Yoshioka, C., Govindasamy, L., An, H., Tu, C., Silverman, D. N. & McKenna, R., 2002, In: Acta Crystallographica Section D: Biological Crystallography. 58, 5, p. 849-852 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Carbonic Anhydrase III 100%
  • Crystallization 68%
  • Isoenzymes 56%
  • X-Rays 43%
  • His-His-His-His-His-His 40%
  5 Scopus citations

• Kinetic analysis of multiple proton shuttles in the active site of human carbonic anhydrase

  Tu, C., Qian, M., An, H., Wadhwa, N. R., Duda, D., Yoshioka, C., Pathak, Y., McKenna, R., Laipis, P. J. & Silverman, D. N., Oct 11 2002, In: Journal of Biological Chemistry. 277, 41, p. 38870-38876 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carbonic Anhydrases 100%
  • Histidine Residue 85%
  • Histidine 82%
  • Carbonic Anhydrase III 79%
  • Protons 76%
  14 Scopus citations