Research output per year
Research output per year
- 1 - 50 out of 127 results
Search results
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2023
Control of stereocilia length during development of hair bundles
Krey, J. F., Chatterjee, P., Halford, J., Cunningham, C. L., Perrin, B. J. & Barr-Gillespie, P. G., Apr 2023, In: PLoS Biology. 21, 4, e3001964.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
GIPC3 couples to MYO6 and PDZ domain proteins, and shapes the hair cell apical region
Chatterjee, P., Morgan, C. P., Krey, J. F., Benson, C., Goldsmith, J., Bateschell, M., Ricci, A. J. & Barr-Gillespie, P. G., May 2023, In: Journal of Cell Science. 136, 10, jcs261100.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
ANKRD24 organizes TRIOBP to reinforce stereocilia insertion points
Krey, J. F., Liu, C., Belyantseva, I. A., Bateschell, M., Dumont, R. A., Goldsmith, J., Chatterjee, P., Morrill, R. S., Fedorov, L. M., Foster, S., Kim, J., Nuttall, A., Jones, S. M., Choi, D., Friedman, T., Ricci, A. J., Zhao, B. & Barr-Gillespie, P. G., Apr 4 2022, In: Journal of Cell Biology. 221, 4, e202109134.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Ca2+ entry through mechanotransduction channels localizes BAIAP2L2 to stereocilia tips
Halford, J., Bateschell, M. & Barr-Gillespie, P. G., Apr 1 2022, In: Molecular biology of the cell. 33, 4, br6.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2021
Cy3-ATP labeling of unfixed, permeabilized mouse hair cells
Pacentine, I. V. & Barr-Gillespie, P. G., Dec 2021, In: Scientific Reports. 11, 1, 23855.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Loss of Baiap2l2 destabilizes the transducing stereocilia of cochlear hair cells and leads to deafness
Carlton, A. J., Halford, J., Underhill, A., Jeng, J. Y., Avenarius, M. R., Gilbert, M. L., Ceriani, F., Ebisine, K., Brown, S. D. M., Bowl, M. R., Barr-Gillespie, P. G. & Marcotti, W., Feb 15 2021, In: Journal of Physiology. 599, 4, p. 1173-1198 26 p.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
2020
A comparative analysis of genetic hearing loss phenotypes in European/American and Japanese populations
Walls, W. D., Moteki, H., Thomas, T. R., Nishio, S. Y., Yoshimura, H., Iwasa, Y., Frees, K. L., Nishimura, C. J., Azaiez, H., Booth, K. T., Marini, R. J., Kolbe, D. L., Weaver, A. M., Schaefer, A. M., Wang, K., Braun, T. A., Usami, S. I., Barr-Gillespie, P. G., Richardson, G. P., Smith, R. J., & 1 others, Oct 1 2020, In: Human genetics. 139, 10, p. 1315-1323 9 p.Research output: Contribution to journal › Article › peer-review
10 Scopus citations -
A cryo-tomography-based volumetric model of the actin core of mouse vestibular hair cell stereocilia lacking plastin 1
Song, J., Patterson, R., Metlagel, Z., Krey, J. F., Hao, S., Wang, L., Ng, B., Sazzed, S., Kovacs, J., Wriggers, W., He, J., Barr-Gillespie, P. G. & Auer, M., Apr 1 2020, In: Journal of Structural Biology. 210, 1, 107461.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations -
Mechanotransduction-Dependent Control of Stereocilia Dimensions and Row Identity in Inner Hair Cells
Krey, J. F., Chatterjee, P., Dumont, R. A., O'Sullivan, M., Choi, D., Bird, J. E. & Barr-Gillespie, P. G., Feb 3 2020, In: Current Biology. 30, 3, p. 442-454.e7Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Stereocilia rootlets: Actin-based structures that are essential for structural stability of the hair bundle
Pacentine, I., Chatterjee, P. & Barr-Gillespie, P. G., Jan 1 2020, In: International journal of molecular sciences. 21, 1, 324.Research output: Contribution to journal › Review article › peer-review
Open Access20 Scopus citations -
2019
Electron cryo-tomography of vestibular hair-cell stereocilia
Metlagel, Z., Krey, J. F., Song, J., Swift, M. F., Tivol, W. J., Dumont, R. A., Thai, J., Chang, A., Seifikar, H., Volkmann, N., Hanein, D., Barr-Gillespie, P. G. & Auer, M., May 1 2019, In: Journal of Structural Biology. 206, 2, p. 149-155 7 p.Research output: Contribution to journal › Article › peer-review
12 Scopus citations -
Molecular composition of vestibular hair bundles
Krey, J. F. & Barr-Gillespie, P. G., Jan 2019, In: Cold Spring Harbor Perspectives in Medicine. 9, 1, a033209.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Single-cell proteomics reveals changes in expression during hair-cell development
Zhu, Y., Scheibinger, M., Ellwanger, D. C., Krey, J. F., Choi, D., Kelly, R. T., Heller, S. & Barr-Gillespie, P. G., Nov 2019, In: eLife. 8, e50777.Research output: Contribution to journal › Article › peer-review
Open Access65 Scopus citations -
2018
Data Descriptor: Mass spectrometry quantitation of proteins from small pools of developing auditory and vestibular cells
Krey, J. F., Scheffer, D. I., Choi, D., Reddy, A., David, L. L., Corey, D. P. & Barr-Gillespie, P. G., Jul 17 2018, In: Scientific Data. 5, 180128.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations -
ELMOD1 stimulates ARF6-GTP hydrolysis to stabilize apical structures in developing vestibular hair cells
Krey, J. F., Dumont, R. A., Wilmarth, P. A., David, L. L., Johnson, K. R. & Barr-Gillespie, P. G., Jan 24 2018, In: Journal of Neuroscience. 38, 4, p. 843-857 15 p.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Honing In on TMC as the Hair Cell's Transduction Channel
Barr-Gillespie, P. G., Aug 22 2018, In: Neuron. 99, 4, p. 628-629 2 p.Research output: Contribution to journal › Short survey › peer-review
Open Access4 Scopus citations -
Transcriptional Dynamics of Hair-Bundle Morphogenesis Revealed with CellTrails
Ellwanger, D. C., Scheibinger, M., Dumont, R. A., Barr-Gillespie, P. G. & Heller, S., Jun 5 2018, In: Cell Reports. 23, 10, p. 2901-2914.e14Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
TRPV6, TRPM6 and TRPM7 do not contribute to hair-cell mechanotransduction
Morgan, C. P., Zhao, H., LeMasurier, M., Xiong, W., Pan, B., Kazmierczak, P., Avenarius, M. R., Bateschell, M., Larisch, R., Ricci, A. J., Müller, U. & Barr-Gillespie, P. G., Feb 20 2018, In: Frontiers in Cellular Neuroscience. 12, 41.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
2017
A Model for Link Pruning to Establish Correctly Polarized and Oriented Tip Links in Hair Bundles
Tompkins, N., Spinelli, K. J., Choi, D. & Barr-Gillespie, P. G., Oct 17 2017, In: Biophysical Journal. 113, 8, p. 1868-1881 14 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Analysis of the Proteome of Hair-Cell Stereocilia by Mass Spectrometry
Krey, J. F., Wilmarth, P. A., David, L. L. & Barr-Gillespie, P. G., 2017, Methods in Enzymology. Academic Press Inc., p. 329-354 26 p. (Methods in Enzymology; vol. 585).Research output: Chapter in Book/Report/Conference proceeding › Chapter
4 Scopus citations -
Corrigendum: Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like (Nature Communications, (2016), 7, 1, (10833), 10.1038/ncomms10833)
Ebrahim, S., Avenarius, M. R., Grati, M., Krey, J. F., Windsor, A. M., Sousa, A. D., Ballesteros, A., Cui, R., Millis, B. A., Salles, F. T., Baird, M. A., Davidson, M. W., Jones, S. M., Choi, D., Dong, L., Raval, M. H., Yengo, C. M., Barr-Gillespie, P. G. & Kachar, B., Dec 22 2017, In: Nature communications. 8, 1, 16133.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Heterodimeric capping protein is required for stereocilia length and width regulation
Avenarius, M. R., Krey, J. F., Dumont, R. A., Morgan, C. P., Benson, C. B., Vijayakumar, S., Cunningham, C. L., Scheffer, D. I., Corey, D. P., Müller, U., Jones, S. M. & Barr-Gillespie, P. G., Nov 1 2017, In: Journal of Cell Biology. 216, 11, p. 3861-3881 21 p.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Integration of Tmc1/2 into the mechanotransduction complex in zebrafish hair cells is regulated by transmembrane o-methyltransferase (Tomt)
Erickson, T., Morgan, C. P., Olt, J., Hardy, K., Busch-Nentwich, E., Maeda, R., Clemens, R., Krey, J. F., Nechiporuk, A., Barr-Gillespie, P. G., Marcotti, W. & Nicolson, T., May 23 2017, In: eLife. 6, e28474.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
2016
Annexin A5 is the Most Abundant Membrane-Associated Protein in Stereocilia but is Dispensable for Hair-Bundle Development and Function
Krey, J. F., Drummond, M., Foster, S., Porsov, E., Vijayakumar, S., Choi, D., Friderici, K., Jones, S. M., Nuttall, A. L. & Barr-Gillespie, P. G., Jun 2 2016, In: Scientific Reports. 6, 27221.Research output: Contribution to journal › Article › peer-review
Open Access19 Scopus citations -
Neuroplastin isoform Np55 is expressed in the stereocilia of outer hair cells and required for normal outer hair cell function
Zeng, W. Z., Grillet, N., Dewey, J. B., Trouillet, A., Krey, J. F., Barr-Gillespie, P. G., Oghalai, J. S. & Müller, U., Aug 31 2016, In: Journal of Neuroscience. 36, 35, p. 9201-9216 16 p.Research output: Contribution to journal › Article › peer-review
Open Access21 Scopus citations -
PDZD7-MYO7A complex identified in enriched stereocilia membranes
Morgan, C. P., Krey, J. F., Grati, M., Zhao, B., Fallen, S., Kannan-Sundhari, A., Liu, X. Z., Choi, D., Müller, U. & Barr-Gillespie, P. G., Aug 15 2016, In: eLife. 5, AUGUST, e18312.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Plastin 1 widens stereocilia by transforming actin filament packing from hexagonal to liquid
Krey, J. F., Krystofiak, E. S., Dumont, R. A., Vijayakumar, S., Choi, D., Rivero, F., Kachar, B., Jones, S. M. & Barr-Gillespie, P. G., 2016, In: Journal of Cell Biology. 215, 4, p. 467-482 16 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Reverse transduction measured in the living cochlea by low-coherence heterodyne interferometry
Ren, T., He, W. & Barr-Gillespie, P. G., Jan 6 2016, In: Nature communications. 7, 10282.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Stereocilia-staircase spacing is influenced by myosin III motors and their cargos espin-1 and espin-like
Ebrahim, S., Avenarius, M. R., Grati, M., Krey, J. F., Windsor, A. M., Sousa, A. D., Ballesteros, A., Cui, R., Millis, B. A., Salles, F. T., Baird, M. A., Davidson, M. W., Jones, S. M., Choi, D., Dong, L., Raval, M. H., Yengo, C. M., Barr-Gillespie, P. G. & Kachar, B., Mar 1 2016, In: Nature communications. 7, 10833.Research output: Contribution to journal › Article › peer-review
Open Access49 Scopus citations -
2015
A short splice form of Xin-actin binding repeat containing 2 (XIRP2) lacking the xin repeats is required for maintenance of stereocilia morphology and hearing function
Francis, S. P., Krey, J. F., Krystofiak, E. S., Cui, R., Nanda, S., Xu, W., Kachar, B., Barr-Gillespie, P. G. & Shin, J. B., 2015, In: Journal of Neuroscience. 35, 5, p. 1999-2014 16 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations -
Assembly of hair bundles, an amazing problem for cell biology
Barr-Gillespie, P. G., Aug 1 2015, In: Molecular biology of the cell. 26, 15, p. 2727-2732 6 p.Research output: Contribution to journal › Review article › peer-review
Open Access80 Scopus citations -
Hair-bundle proteomes of avian and mammalian inner-ear utricles
Wilmarth, P. A., Krey, J. F., Shin, J. B., Choi, D., David, L. L. & Barr-Gillespie, P. G., Dec 8 2015, In: Scientific Data. 2, 150074.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
New treatment options for hearing loss
Müller, U. & Barr-Gillespie, P. G., May 5 2015, In: Nature Reviews Drug Discovery. 14, 5, p. 346-365 20 p.Research output: Contribution to journal › Review article › peer-review
121 Scopus citations -
The proteome of mouse vestibular hair bundles over development
Krey, J. F., Sherman, N. E., Jeffery, E. D., Choi, D. & Barr-Gillespie, P. G., Sep 15 2015, In: Scientific Data. 2, 150047.Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
2014
Accurate label-free protein quantitation with high- and low-resolution mass spectrometers
Krey, J. F., Wilmarth, P. A., Shin, J. B., Klimek, J., Sherman, N. E., Jeffery, E. D., Choi, D., David, L. L. & Barr-Gillespie, P. G., Feb 7 2014, In: Journal of Proteome Research. 13, 2, p. 1034-1044 11 p.Research output: Contribution to journal › Article › peer-review
100 Scopus citations -
Correlation of actin crosslinker and capper expression levels with stereocilia growth phases
Avenarius, M. R., Saylor, K. W., Lundeberg, M. R., Wilmarth, P. A., Shin, J. B., Spinelli, K. J., Pagana, J. M., Andrade, L., Kachar, B., Choi, D., David, L. L. & Barr-Gillespie, P. G., Feb 2014, In: Molecular and Cellular Proteomics. 13, 2, p. 606-620 15 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Scopus citations -
The local forces acting on the mechanotransduction channel in hair cell stereocilia
Powers, R. J., Kulason, S., Atilgan, E., Brownell, W. E., Sun, S. X., Barr-Gillespie, P. G. & Spector, A. A., Jun 3 2014, In: Biophysical Journal. 106, 11, p. 2519-2528 10 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2
Maeda, R., Kindt, K. S., Mo, W., Morgan, C. P., Erickson, T., Zhao, H., Clemens-Grisham, R., Barr-Gillespie, P. G. & Nicolson, T., Sep 2 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 35, p. 12907-12912 6 p.Research output: Contribution to journal › Article › peer-review
Open Access115 Scopus citations -
2013
Erratum: High-resolution structure of hair-cell tip links (Proceedings of the National Academy of Sciences of the United States of America (2000) 97 (13336-13341) DOI: 10.1073/pnas.97.24.13336)
Kachar, B., Parakkal, M., Kurc, M., Zhao, Y. D. & Gillespie, P. G., Jul 16 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 29, p. 12155 1 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access1 Scopus citations -
Mechanotransduction: The elusive hair cell transduction channel revealed?
Morgan, C. P. & Barr-Gillespie, P. G., Oct 7 2013, In: Current Biology. 23, 19, p. R887-R890Research output: Contribution to journal › Short survey › peer-review
Open Access8 Scopus citations -
Molecular architecture of the chick vestibular hair bundle
Shin, J. B., Krey, J. F., Hassan, A., Metlagel, Z., Tauscher, A. N., Pagana, J. M., Sherman, N. E., Jeffery, E. D., Spinelli, K. J., Zhao, H., Wilmarth, P. A., Choi, D., David, L. L., Auer, M. & Barr-Gillespie, P. G., Mar 2013, In: Nature Neuroscience. 16, 3, p. 365-374 10 p.Research output: Contribution to journal › Article › peer-review
136 Scopus citations -
Molecular Remodeling of Tip Links Underlies Mechanosensory Regeneration in Auditory Hair Cells
Indzhykulian, A. A., Stepanyan, R., Nelina, A., Spinelli, K. J., Ahmed, Z. M., Belyantseva, I. A., Friedman, T. B., Barr-Gillespie, P. G. & Frolenkov, G. I., Jun 2013, In: PLoS Biology. 11, 6, e1001583.Research output: Contribution to journal › Article › peer-review
Open Access86 Scopus citations -
Who needs tip links? Backwards transduction by hair cells
Barr-Gillespie, P. G. & Nicolson, T., Nov 2013, In: Journal of General Physiology. 142, 5, p. 481-486 6 p.Research output: Contribution to journal › Comment/debate › peer-review
Open Access7 Scopus citations -
2012
Digenic inheritance of deafness caused by 8J allele of myosin-VIIA and mutations in other Usher I genes
Zheng, Q. Y., Scarborough, J. D., Zheng, Y., Yu, H., Choi, D. & Gillespie, P. G., Jun 2012, In: Human molecular genetics. 21, 11, p. 2588-2598 11 p., dds084.Research output: Contribution to journal › Article › peer-review
Open Access23 Scopus citations -
Distinct energy metabolism of auditory and vestibular sensory epithelia revealed by quantitative mass spectrometry using MS2 intensity
Spinelli, K. J., Klimek, J. E., Wilmarth, P. A., Shin, J. B., Choi, D., David, L. L. & Gillespie, P. G., Jan 31 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 5, p. E268-E277Research output: Contribution to journal › Article › peer-review
Open Access29 Scopus citations -
Improved Biolistic Transfection of Hair Cells
Zhao, H., Avenarius, M. R. & Gillespie, P. G., Oct 1 2012, In: PloS one. 7, 10, e46765.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Large membrane domains in hair bundles specify spatially constricted radixin activation
Zhao, H., Williams, D. E., Shin, J. B., Brügger, B. & Gillespie, P. G., Mar 28 2012, In: Journal of Neuroscience. 32, 13, p. 4600-4609 10 p.Research output: Contribution to journal › Article › peer-review
Open Access39 Scopus citations -
Localization of PDZD7 to the stereocilia ankle-link associates this scaffolding protein with the usher syndrome protein network
Grati, M., Shin, J. B., Weston, M. D., Green, J., Bhat, M. A., Gillespie, P. G. & Kachar, B., Oct 10 2012, In: Journal of Neuroscience. 32, 41, p. 14288-14293 6 p.Research output: Contribution to journal › Article › peer-review
Open Access55 Scopus citations -
Monitoring Intracellular Calcium Ion Dynamics in Hair Cell Populations with Fluo-4 AM
Spinelli, K. J. & Gillespie, P. G., Dec 17 2012, In: PloS one. 7, 12, e51874.Research output: Contribution to journal › Article › peer-review
Open Access25 Scopus citations -
Probing the Cochlear Amplifier by Immobilizing Molecular Motors of Sensory Hair Cells
Ren, T. & Gillespie, P. G., Dec 6 2012, In: Neuron. 76, 5, p. 868-870 3 p.Research output: Contribution to journal › Short survey › peer-review
Open Access1 Scopus citations